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NCT02530034 · ClinicalTrials.gov registry record · Phase 1

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

A Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 1
Development phase
72
Enrollment target
4
Study locations

NCT02530034 is a Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 72 participants, below the 952-participant average among 104 other Hematopoietic and Lymphoid Cell Neoplasm trials with a reported enrollment target (92% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT02530034, a Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
72 participants
Enrollment target
4
Study locations

Study Summary

This phase I trial studies the side effects and best dose of anti-PR1/HLA-A2 monoclonal antibody Hu8F4 (Hu8F4) in treating patients with malignancies related to the blood (hematologic). Monoclonal antibodies, such as Hu8F4, may interfere with the ability of cancer cells to grow and spread.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • OTHER Pharmacological Study
  • DRUG Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4

Study Locations (4)

Georgia

  • Augusta University - Augusta

New York

  • Montefiore Medical Center, Albert Einstein College of Medicine - The Bronx

Texas

  • M D Anderson Cancer Center - Houston

Utah

  • Huntsman Cancer Institute - Salt Lake City

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2019-01-31
Est. Completion 2027-01-01
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT02530034

The ClinicalTrials.gov registry entry for NCT02530034 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 952-participant average among 104 other Hematopoietic and Lymphoid Cell Neoplasm trials with a reported enrollment target (92% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Hematopoietic and Lymphoid Cell Neoplasm appearing as the primary indexed condition, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT02530034 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Georgia, New York, Texas.

Frequently Asked Questions

What is clinical trial NCT02530034 about?

NCT02530034 is a clinical study titled "Hu8F4 in Treating Patients With Advanced Hematologic Malignancies". This phase I trial studies the side effects and best dose of anti-PR1/HLA-A2 monoclonal antibody Hu8F4 (Hu8F4) in treating patients with malignancies related to the blood (hematologic). Monoclonal antibodies, such as Hu8F4, may interfere with the ability of cancer cells to grow and spread.

What is the current status of trial NCT02530034?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2019-01-31. Estimated completion is 2027-01-01.

What conditions does trial NCT02530034 study?

This clinical trial studies the following conditions: Hematopoietic and Lymphoid Cell Neoplasm, Myelofibrosis, Recurrent Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, High Risk Myelodysplastic Syndrome.

What interventions are being tested in trial NCT02530034?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Pharmacological Study (OTHER), Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4 (DRUG).

Who is sponsoring clinical trial NCT02530034?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02530034 being conducted?

This trial has 4 study locations across Georgia, New York, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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