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NCT02530034 · ClinicalTrials.gov registry record · Phase 1
Hu8F4 in Treating Patients With Advanced Hematologic Malignancies
A Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
- 4
- Study locations
NCT02530034: Active Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis, sponsored by M.D. Anderson Cancer Center.
NCT02530034 is a Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 72 participants, below the 952-participant average among 104 other Hematopoietic and Lymphoid Cell Neoplasm trials with a reported enrollment target (92% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02530034, a Phase 1 study of Hematopoietic and Lymphoid Cell Neoplasm and Myelofibrosis, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
- 4
- Study locations
Study Summary
This phase I trial studies the side effects and best dose of anti-PR1/HLA-A2 monoclonal antibody Hu8F4 (Hu8F4) in treating patients with malignancies related to the blood (hematologic). Monoclonal antibodies, such as Hu8F4, may interfere with the ability of cancer cells to grow and spread.
Primary Outcome
Safety data will be summarized using frequency and percentage for all patients.
Conditions Studied
Interventions
- OTHER Laboratory Biomarker Analysis
- OTHER Pharmacological Study
- DRUG Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4
Study Locations (4)
Georgia
- Augusta University - Augusta
New York
- Montefiore Medical Center, Albert Einstein College of Medicine - The Bronx
Texas
- M D Anderson Cancer Center - Houston
Utah
- Huntsman Cancer Institute - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2019-01-31 |
| Est. Completion | 2027-01-01 |
| Phase | Phase 1 |
What the registry record for NCT02530034 still lists
NCT02530034 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 952-participant average among 104 other Hematopoietic and Lymphoid Cell Neoplasm trials with a reported enrollment target (92% lower).
The record links to 10 conditions, with Hematopoietic and Lymphoid Cell Neoplasm appearing as the primary indexed condition, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.
NCT02530034 reports a single indexed study location in Georgia, New York, Texas.
Frequently Asked Questions
What is clinical trial NCT02530034 about?
NCT02530034 is a clinical study titled "Hu8F4 in Treating Patients With Advanced Hematologic Malignancies". This phase I trial studies the side effects and best dose of anti-PR1/HLA-A2 monoclonal antibody Hu8F4 (Hu8F4) in treating patients with malignancies related to the blood (hematologic). Monoclonal antibodies, such as Hu8F4, may interfere with the ability of cancer cells to grow and spread.
What is the current status of trial NCT02530034?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2019-01-31. Estimated completion is 2027-01-01.
What conditions does trial NCT02530034 study?
This clinical trial studies the following conditions: Hematopoietic and Lymphoid Cell Neoplasm, Myelofibrosis, Recurrent Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, High Risk Myelodysplastic Syndrome.
What interventions are being tested in trial NCT02530034?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Pharmacological Study (OTHER), Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4 (DRUG).
Who is sponsoring clinical trial NCT02530034?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02530034 being conducted?
This trial has 4 study locations across Georgia, New York, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02530034's enrollment target sits among peer trials
72 53rd of 104 higher than 51 of 104 other Hematopoietic and Lymphoid Cell Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hematopoietic and Lymphoid Cell Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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