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ClinicalTrials.gov 49 recruiting now early-phase tilt #113 of 28,707 conditions

Healthy Volunteer: early-phase trial registry

49 of 113 indexed Healthy Volunteer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #113 of 28,707 conditions by registered trial count.

113 US clinical trials · 49 currently recruiting · #113 of 28,707 conditions by registered trial count

Healthy Volunteer: 113 US clinical trials tracked, 49 recruiting.

Healthy Volunteer is the subject of 113 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 86 in Phase 1-2 (earlier-stage). The most active sponsor is AbbVie, running 15 of these trials.

Enrollment posture brief

Registry condition healthy-volunteer

OPEN 49 | RECR 43% | LATE 0 | EARLY 86 | RANK #113 | SPON 15

Nearest open-share peer: Bronchopulmonary Dysplasia (43% recruiting · 30 trials)

Diffuse Large B Cell Lymphom46.1%Healthy Volunteer (this)43%Pain, Postoperative40.4%Type 1 Diabetes Mellitus22.1%Unspecified Adult Solid Tumo4.5%
Open-enrollment share among volume-matched conditions near Healthy Volunteer

Healthy Volunteer lists 49 open slots (43% of 113 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Healthy Volunteer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Healthy Volunteer is recruiting above its size-band peers.

    49 of 113 indexed trials (43.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Healthy Volunteer trials is spread across many organizations.

    AbbVie accounts for 15 of 113 trials (13.3%). 56 distinct sponsors appear on at least one study for this condition label.

  3. Most Healthy Volunteer trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 113 trials that report a genuine target (sentinel values excluded). 80 of those (70.8%) plan for fewer than 100 participants.

  4. Healthy Volunteer research is mostly interventional.

    95 interventional and 18 observational studies make up this index (84.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 180Phase 26

Open and recent trials

113 total, page 3 of 3

COMPLETED Phase 1 24 participants

A Study to Assess Drug-Drug Interaction Between ABBV-903 and Midazolam in Adult Healthy Volunteers

AbbVie

NCT05895266

COMPLETED Phase 1 24 participants

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

INSYS Therapeutics

NCT03827629

COMPLETED Phase 1 22 participants

Study of SAGE-904 Using a Ketamine Challenge to Evaluate Electrophysiology, Safety, Tolerability, and Pharmacokinetics in Healthy Participants

Supernus Pharmaceuticals

NCT05049343

COMPLETED Phase 1 17 participants

A Study to Assess How Food Affects the Movement of Oral ABBV-101 Through the Body of Healthy Adult Participants

AbbVie

NCT06887010

COMPLETED Phase 1 15 participants

A Bioavailability and Pharmacokinetic Study of GDC-0032 in Healthy Volunteers

Genentech

NCT01967966

COMPLETED Phase 1 15 participants

Vaccine to Prevent West Nile Virus Disease

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00106769

COMPLETED Phase 1 12 participants

Proton Pump Inhibitor (PPI, Rabeprazole) Effect On Tablet Formulation Of Palbociclib

Pfizer

NCT03220191

COMPLETED Phase 1 12 participants

A Study to Assess Change in How Oral Icalcaprant With Itraconazole Moves Through the Body in Healthy Adult Participants

AbbVie

NCT06722430

COMPLETED NA 10 participants

Caloric Stimulation on Cerebral Blood Flow

Duke University

NCT01629901

COMPLETED 10 participants

A Quantitative Optical Sensor to Monitor Vascular Physiology; A Healthy Volunteer Study

Zenalux Biomedical

NCT02321995

COMPLETED Phase 1 8 participants

A Study to Look at How a Single Oral Dose of Carbon-14-Labelled [14C] BIIB091 Moves Through and is Processed by the Body in Healthy Male Participants

Biogen

NCT06311786

COMPLETED Phase 1 6 participants

A Pharmacokinetics Study of Radioactive-Labeled GDC-0973 in Healthy Male Volunteers

Genentech

NCT01711762

COMPLETED Phase 1 3 participants

Occupancy of Adenosine A2A Receptors Using the PET Radiotracer [18F]MNI-444

Invicro

NCT05009199

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 6

Named interventions

Most-linked intervention names on Healthy Volunteer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
27 trials
[18F]NOS Drug
3 trials
Itraconazole Drug
3 trials
GDC-0032 Drug
2 trials
ABBV-8736 Drug
2 trials
Carbamazepine Drug
2 trials
ABBV-932 Drug
2 trials
Esomeprazole Drug
2 trials

US sites by state

Facility locations filed on Healthy Volunteer trials. A trial with sites in several states counts in each.

Maryland 26 trials
Texas 19 trials
Illinois 17 trials
California 13 trials
New Jersey 7 trials
Kansas 7 trials
Florida 7 trials
Connecticut 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Healthy Volunteer page

113 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 49 Healthy Volunteer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • AbbVie sponsors the most Healthy Volunteer trials on record, review their full trial history before evaluating a specific study. See AbbVie's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Volunteer condition card totals 113 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.