Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07185321 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study of Mosliciguat in Healthy, Adult Males
A Phase 1 study of Healthy Volunteer, sponsored by Pulmovant.
- Active
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
- 1
- Study location
NCT07185321: Active Phase 1 study of Healthy Volunteer, sponsored by Pulmovant.
NCT07185321 is a Phase 1 study of Healthy Volunteer that is active but no longer recruiting, run by Pulmovant. The registered enrollment target is 8 participants, below the 202-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07185321, a Phase 1 study of Healthy Volunteer, is active but no longer recruiting, sponsored by Pulmovant.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single-center, Phase 1, open-label, 3-period, fixed-sequence study to investigate the bioavailability, absorption, metabolism, excretion and the safety of mosliciguat administered to healthy male adults.
Primary Outcome
Absolute bioavailability of inhaled mosliciguat
Conditions Studied
Interventions
- DEVICE Dry Powder Inhaler
- DRUG Mosliciguat
- DRUG 14C mosliciguat
Study Locations (1)
Maryland
- Pharmaron - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2025-06-10 |
| Est. Completion | 2026-05 |
| Phase | Phase 1 |
What the registry record for NCT07185321 still lists
NCT07185321 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 202-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Healthy Volunteer appearing as the primary indexed condition, and to 3 interventions - of which Dry Powder Inhaler is the first listed.
NCT07185321 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT07185321 about?
NCT07185321 is a clinical study titled "A Phase 1 Study of Mosliciguat in Healthy, Adult Males". This is a single-center, Phase 1, open-label, 3-period, fixed-sequence study to investigate the bioavailability, absorption, metabolism, excretion and the safety of mosliciguat administered to healthy male adults.
What is the current status of trial NCT07185321?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2025-06-10. Estimated completion is 2026-05.
What conditions does trial NCT07185321 study?
This clinical trial studies the following conditions: Healthy Volunteer.
What interventions are being tested in trial NCT07185321?
The interventions under investigation include: Dry Powder Inhaler (DEVICE), Mosliciguat (DRUG), 14C mosliciguat (DRUG).
Who is sponsoring clinical trial NCT07185321?
This trial is sponsored by Pulmovant, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07185321 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07185321's enrollment target sits among peer trials
8 110th of 112 higher than 2 of 112 other Healthy Volunteer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Healthy Volunteer Study
RECRUITING · Phase 1
-
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
RECRUITING · Phase 1
-
Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors
RECRUITING · Phase 1
-
A First-in-Human Single and Multiple Ascending Dose Study of MT-201
RECRUITING · Phase 1
-
A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants
RECRUITING · Phase 1
-
A Study to Assess How the Drug Moves Through the Body, Adverse Events, and Tolerability of Oral ABBV-722 Capsules of Single and Multiple Ascending Doses in Adult Participants and Single Doses in Adult Asian Participants
RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI