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NCT05355935 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants
A Phase 1 study of Healthy Volunteer, sponsored by Insmed Incorporated.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT05355935: Completed Phase 1 study of Healthy Volunteer, sponsored by Insmed Incorporated.
NCT05355935 is a Phase 1 study of Healthy Volunteer that has completed, run by Insmed Incorporated. The registered enrollment target is 48 participants, below the 201-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05355935, a Phase 1 study of Healthy Volunteer, has completed, sponsored by Insmed Incorporated.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The study has 2 Parts: The primary purpose of Part 1 is to determine the supratherapeutic dose of brensocatib to be used in Part 2 of the study. The primary purpose of Part 2 is to assess brensocatib's potential for prolonging the QT interval.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Moxifloxacin
- DRUG Brensocatib
Study Locations (1)
Wisconsin
- USA001 - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-04-27 |
| Est. Completion | 2022-10-07 |
| Phase | Phase 1 |
What the finished NCT05355935 record still lists
NCT05355935 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 201-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Healthy Volunteer appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05355935 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05355935 about?
NCT05355935 is a clinical study titled "A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants". The study has 2 Parts: The primary purpose of Part 1 is to determine the supratherapeutic dose of brensocatib to be used in Part 2 of the study. The primary purpose of Part 2 is to assess brensocatib's potential for prolonging the QT interval.
What is the current status of trial NCT05355935?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2022-04-27. Estimated completion is 2022-10-07.
What conditions does trial NCT05355935 study?
This clinical trial studies the following conditions: Healthy Volunteer.
What interventions are being tested in trial NCT05355935?
The interventions under investigation include: Placebo (DRUG), Moxifloxacin (DRUG), Brensocatib (DRUG).
Who is sponsoring clinical trial NCT05355935?
This trial is sponsored by Insmed Incorporated, which has 31 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05355935 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05355935's enrollment target sits among peer trials
48 59th of 112 higher than 52 of 112 other Healthy Volunteer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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