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NCT04839393 · ClinicalTrials.gov registry record · Phase 1

A Drug-Drug Interaction Study Between PF-06882961 and PF-06865571 in Healthy Adult Participants and Overweight Adults or Adults With Obesity Who Are Otherwise Healthy

A Phase 1 study of Healthy Volunteer, sponsored by Pfizer.

Completed
Registry status
Phase 1
Development phase
27
Enrollment target
1
Study location

NCT04839393: Completed Phase 1 study of Healthy Volunteer, sponsored by Pfizer.

NCT04839393 is a Phase 1 study of Healthy Volunteer that has completed, run by Pfizer. The registered enrollment target is 27 participants, below the 202-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04839393, a Phase 1 study of Healthy Volunteer, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
27 participants
Enrollment target
1
Study location

Study Summary

This study will be conducted in 2 parts. Part A will investigate the potential effect of PF-06865571 on the pharmacokinetics (PK) of PF-06882961 in healthy adult participants. Part B will evaluate the effect of PF-06882961 on the PK of PF-06865571, as well as the effect of PF-06865571 on the PK of PF-06882961 in overweight adults or adults with obesity who are otherwise healthy.

Primary Outcome

Cmax for PF-06882961 was observed directly from data.

Conditions Studied

Interventions

  • DRUG PF-06882961 followed by PF-06882961/PF-06865571
  • DRUG PF-06882961/PF-06865571 followed by PF-06882961
  • DRUG PF-06882961 + PF-06865571

Study Locations (1)

California

  • Orange County Research Center - Tustin

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2021-04-05
Est. Completion 2021-11-08
Phase Phase 1
Pfizer

1,845 total trials

What the finished NCT04839393 record still lists

NCT04839393 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 202-participant average among 112 other Healthy Volunteer trials with a reported enrollment target (87% lower).

The record links to 1 condition, with Healthy Volunteer appearing as the primary indexed condition, and to 3 interventions - of which PF-06882961 followed by PF-06882961/PF-06865571 is the first listed.

NCT04839393 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04839393 about?

NCT04839393 is a clinical study titled "A Drug-Drug Interaction Study Between PF-06882961 and PF-06865571 in Healthy Adult Participants and Overweight Adults or Adults With Obesity Who Are Otherwise Healthy". This study will be conducted in 2 parts. Part A will investigate the potential effect of PF-06865571 on the pharmacokinetics (PK) of PF-06882961 in healthy adult participants. Part B will evaluate the effect of PF-06882961 on the PK of PF-06865571, as well as the effect of PF-06865571 on the PK of P...

What is the current status of trial NCT04839393?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2021-04-05. Estimated completion is 2021-11-08.

What conditions does trial NCT04839393 study?

This clinical trial studies the following conditions: Healthy Volunteer.

What interventions are being tested in trial NCT04839393?

The interventions under investigation include: PF-06882961 followed by PF-06882961/PF-06865571 (DRUG), PF-06882961/PF-06865571 followed by PF-06882961 (DRUG), PF-06882961 + PF-06865571 (DRUG).

Who is sponsoring clinical trial NCT04839393?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04839393 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04839393's enrollment target sits among peer trials

27 80th of 112 higher than 31 of 112 other Healthy Volunteer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04839393, the US trial registry maintained by the National Library of Medicine. NCT04839393 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.