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NCT07222020 · ClinicalTrials.gov registry record · Phase 1
Phase 1 Study of Intravaginal KB15A
A Phase 1 study of Healthy Subjects, sponsored by ZabBio.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT07222020 is a Phase 1 study of Healthy Subjects that is actively recruiting participants, run by ZabBio. The registered enrollment target is 24 participants, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07222020, a Phase 1 study of Healthy Subjects, is actively recruiting participants, sponsored by ZabBio.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to determine the safety and mucosal pharmacokinetics of KB15A, a vaginal film containing an anti-sperm monoclonal antibody, in healthy adult women. Researchers will compare KB15A use to placebo use, primarily to see if KB15A is associated with adverse events, and also to understand the local and systemic distribution of the KB15A monoclonal antibody following use of the vaginal film. Participants will be assessed for the genital, mucosal and systemic safety and pharmacokinetics of KB15A in a preliminary single-dose phase of the study, where they will receive two single doses of either KB15A or placebo vaginal film, and again in a multiple-dose phase of the study, where they will receive 14 daily doses of either KB15A or placebo vaginal film.
Conditions Studied
Interventions
- DRUG KB15A Vaginal Film
- DRUG Placebo Vaginal Film
Study Locations (1)
Virginia
- Virginia Health Sciences at Old Dominion University - Norfolk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-01-01 |
| Est. Completion | 2026-12-28 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07222020
The ClinicalTrials.gov registry entry for NCT07222020 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (81% lower). The listed sponsor is ZabBio, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Subjects appearing as the primary indexed condition, and to 2 interventions - of which KB15A Vaginal Film is the first listed.
NCT07222020 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.
Frequently Asked Questions
What is clinical trial NCT07222020 about?
NCT07222020 is a clinical study titled "Phase 1 Study of Intravaginal KB15A". The goal of this clinical trial is to determine the safety and mucosal pharmacokinetics of KB15A, a vaginal film containing an anti-sperm monoclonal antibody, in healthy adult women. Researchers will compare KB15A use to placebo use, primarily to see if KB15A is associated with adverse events, and a...
What is the current status of trial NCT07222020?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2026-01-01. Estimated completion is 2026-12-28.
What conditions does trial NCT07222020 study?
This clinical trial studies the following conditions: Healthy Subjects.
What interventions are being tested in trial NCT07222020?
The interventions under investigation include: KB15A Vaginal Film (DRUG), Placebo Vaginal Film (DRUG).
Who is sponsoring clinical trial NCT07222020?
This trial is sponsored by ZabBio, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07222020 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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