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NCT05612074 · ClinicalTrials.gov registry record · Early Phase 1
Methemoglobin Concentration in High Dose Inhaled Nitric Oxide
A Early Phase 1 study of Healthy Subjects, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- Early Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT05612074: Active Early Phase 1 study of Healthy Subjects, sponsored by Massachusetts General Hospital.
NCT05612074 is a Early Phase 1 study of Healthy Subjects that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 10 participants, below the 129-participant average among 69 other Healthy Subjects trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05612074, a Early Phase 1 study of Healthy Subjects, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn about the kinetic of methemoglobin in healthy subjects breathing high dose inhaled nitric oxide. The main questions it aims to answer are: * What are the kinetics of methemoglobin formation at a maximum of 300 parts per million of nitric oxide and oxygen * What are the kinetics of methemoglobin reduction after nitric oxide discontinuation Participants will be exposed to intermittent high dose inhaled nitric oxide at a maximum of 300 parts per million while being continuously monitored.
Primary Outcome
Levels of methemoglobin formation and reduction during and after exposure to high dose inhaled nitric oxide
Conditions Studied
Interventions
- DRUG Inhaled Nitric Oxide
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2023-10-16 |
| Est. Completion | 2027-12 |
| Phase | Early Phase 1 |
What the registry record for NCT05612074 still lists
NCT05612074 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 129-participant average among 69 other Healthy Subjects trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Healthy Subjects appearing as the primary indexed condition, and to 1 intervention - of which Inhaled Nitric Oxide is the first listed.
NCT05612074 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05612074 about?
NCT05612074 is a clinical study titled "Methemoglobin Concentration in High Dose Inhaled Nitric Oxide". The goal of this clinical trial is to learn about the kinetic of methemoglobin in healthy subjects breathing high dose inhaled nitric oxide. The main questions it aims to answer are: * What are the kinetics of methemoglobin formation at a maximum of 300 parts per million of nitric oxide and oxygen...
What is the current status of trial NCT05612074?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2023-10-16. Estimated completion is 2027-12.
What conditions does trial NCT05612074 study?
This clinical trial studies the following conditions: Healthy Subjects.
What interventions are being tested in trial NCT05612074?
The interventions under investigation include: Inhaled Nitric Oxide (DRUG).
Who is sponsoring clinical trial NCT05612074?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05612074 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05612074's enrollment target sits among peer trials
10 65th of 69 higher than 5 of 69 other Healthy Subjects trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Subjects trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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