Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05612074 · ClinicalTrials.gov registry record · Early Phase 1

Methemoglobin Concentration in High Dose Inhaled Nitric Oxide

A Early Phase 1 study of Healthy Subjects, sponsored by Massachusetts General Hospital.

Active
Registry status
Early Phase 1
Development phase
10
Enrollment target
1
Study location

NCT05612074 is a Early Phase 1 study of Healthy Subjects that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 10 participants, below the 129-participant average among 69 other Healthy Subjects trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05612074, a Early Phase 1 study of Healthy Subjects, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn about the kinetic of methemoglobin in healthy subjects breathing high dose inhaled nitric oxide. The main questions it aims to answer are: * What are the kinetics of methemoglobin formation at a maximum of 300 parts per million of nitric oxide and oxygen * What are the kinetics of methemoglobin reduction after nitric oxide discontinuation Participants will be exposed to intermittent high dose inhaled nitric oxide at a maximum of 300 parts per million while being continuously monitored.

Conditions Studied

Interventions

  • DRUG Inhaled Nitric Oxide

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2023-10-16
Est. Completion 2027-12
Phase Early Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT05612074

The ClinicalTrials.gov registry entry for NCT05612074 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 129-participant average among 69 other Healthy Subjects trials with a reported enrollment target (92% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Subjects appearing as the primary indexed condition, and to 1 intervention - of which Inhaled Nitric Oxide is the first listed.

NCT05612074 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05612074 about?

NCT05612074 is a clinical study titled "Methemoglobin Concentration in High Dose Inhaled Nitric Oxide". The goal of this clinical trial is to learn about the kinetic of methemoglobin in healthy subjects breathing high dose inhaled nitric oxide. The main questions it aims to answer are: * What are the kinetics of methemoglobin formation at a maximum of 300 parts per million of nitric oxide and oxygen...

What is the current status of trial NCT05612074?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2023-10-16. Estimated completion is 2027-12.

What conditions does trial NCT05612074 study?

This clinical trial studies the following conditions: Healthy Subjects.

What interventions are being tested in trial NCT05612074?

The interventions under investigation include: Inhaled Nitric Oxide (DRUG).

Who is sponsoring clinical trial NCT05612074?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05612074 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Subjects

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.