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NCT03869372 · ClinicalTrials.gov registry record · NA
Cerebral Cortical Influences on Autonomic Function
A NA study of Healthy Subjects and Irritable Bowel Syndrome, sponsored by David Levinthal.
- Active
- Registry status
- NA
- Development phase
- 244
- Enrollment target
- 1
- Study location
NCT03869372: Active NA study of Healthy Subjects and Irritable Bowel Syndrome, sponsored by David Levinthal.
NCT03869372 is a NA study of Healthy Subjects and Irritable Bowel Syndrome that is active but no longer recruiting, run by David Levinthal. The registered enrollment target is 244 participants, above the 125-participant average among 69 other Healthy Subjects trials with a reported enrollment target (95% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03869372, a NA study of Healthy Subjects and Irritable Bowel Syndrome, is active but no longer recruiting, sponsored by David Levinthal.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 244 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an exploratory neurophysiological study that will determine the impact of non-invasive brain stimulation on autonomic regulation, with a focus on gastrointestinal function. These studies should provide a basis for future brain-based neurotherapeutic strategies in patients with functional GI disorders.
Primary Outcome
The EGG will be analyzed in the frequency domain using fast Fourier Transformation (FFT). The power spectrum will be divided into frequency bands (normal gastric activity (\~3 cycles per minute), slower than normal (bradygastria) and faster than normal (tachygastria)). rTMS-induced shifts in the power distribution across these frequency bands after consumption of water or a nutrient drink or a test meal will be compared to water or nutrient drink or test meal without rTMS.
Conditions Studied
Interventions
- DEVICE rTMS
Study Locations (1)
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 244 participants |
| Start Date | 2019-04-05 |
| Est. Completion | 2026-10-03 |
| Phase | NA |
What the registry record for NCT03869372 still lists
NCT03869372 is an interventional study that assigns participants to a tested intervention. The registered 244 participants enrollment target is mid-sized for trials with a published cap, above the 125-participant average among 69 other Healthy Subjects trials with a reported enrollment target (95% higher).
The record links to 3 conditions, with Healthy Subjects appearing as the primary indexed condition, and to 1 intervention - of which rTMS is the first listed.
NCT03869372 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03869372 about?
NCT03869372 is a clinical study titled "Cerebral Cortical Influences on Autonomic Function". This is an exploratory neurophysiological study that will determine the impact of non-invasive brain stimulation on autonomic regulation, with a focus on gastrointestinal function. These studies should provide a basis for future brain-based neurotherapeutic strategies in patients with functional GI ...
What is the current status of trial NCT03869372?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 244 participants. The study started on 2019-04-05. Estimated completion is 2026-10-03.
What conditions does trial NCT03869372 study?
This clinical trial studies the following conditions: Healthy Subjects, Irritable Bowel Syndrome, Functional Dyspepsia.
What interventions are being tested in trial NCT03869372?
The interventions under investigation include: rTMS (DEVICE).
Who is sponsoring clinical trial NCT03869372?
This trial is sponsored by David Levinthal, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03869372 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03869372's enrollment target sits among peer trials
244 6th of 69 higher than 64 of 69 other Healthy Subjects trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Subjects trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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