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NCT06014515 · ClinicalTrials.gov registry record · Early Phase 1

Single-tracer Multiparametric PET Imaging

A Early Phase 1 study of Cardiovascular Disease and Healthy Subjects, sponsored by University of California, Davis.

Recruiting
Registry status
Early Phase 1
Development phase
60
Enrollment target
1
Study location

NCT06014515: Recruiting Early Phase 1 study of Cardiovascular Disease and Healthy Subjects, sponsored by University of California, Davis.

NCT06014515 is a Early Phase 1 study of Cardiovascular Disease and Healthy Subjects that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 60 participants, below the 2,697-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06014515, a Early Phase 1 study of Cardiovascular Disease and Healthy Subjects, is actively recruiting participants, sponsored by University of California, Davis.

RECRUITING
Registry status
Early Phase 1
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The overarching goal of this project is to develop and evaluate a single-tracer multiparametric positron emission tomography (PET) imaging solution for simultaneous imaging of blood flow and glucose metabolism using 18F-fluorodeoxyglucose (FDG) alone. The investigators working hypothesis is that quantitative blood flow can be extracted from dynamic 18F-FDG PET data by use of tracer kinetic modeling, in addition to glucose metabolism that 18F-FDG is conventionally used for.

Primary Outcome

The primary study endpoint is to evaluate if the blood flow estimated with 18F-FDG is quantitatively equal to the blood flow measured with the flow-dedicated tracer 11C-butanol measured in ml/min/g.

Interventions

  • DRUG 18F-FDG
  • DRUG 11C-butanol

Study Locations (1)

California

  • UC Davis EXPLORER Molecular Imaging Center - Sacramento

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2024-02-14
Est. Completion 2033-08
Phase Early Phase 1
University of California, Davis

657 total trials

What NCT06014515 shows while recruiting

NCT06014515 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,697-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (98% lower).

The record links to 2 conditions, with Cardiovascular Disease appearing as the primary indexed condition, and to 2 interventions - of which 18F-FDG is the first listed.

NCT06014515 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06014515 about?

NCT06014515 is a clinical study titled "Single-tracer Multiparametric PET Imaging". The overarching goal of this project is to develop and evaluate a single-tracer multiparametric positron emission tomography (PET) imaging solution for simultaneous imaging of blood flow and glucose metabolism using 18F-fluorodeoxyglucose (FDG) alone. The investigators working hypothesis is that qua...

What is the current status of trial NCT06014515?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 60 participants. The study started on 2024-02-14. Estimated completion is 2033-08.

What conditions does trial NCT06014515 study?

This clinical trial studies the following conditions: Cardiovascular Disease, Healthy Subjects.

What interventions are being tested in trial NCT06014515?

The interventions under investigation include: 18F-FDG (DRUG), 11C-butanol (DRUG).

Who is sponsoring clinical trial NCT06014515?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06014515 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiovascular Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06014515's enrollment target sits among peer trials

60 101st of 137 higher than 34 of 137 other Cardiovascular Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiovascular Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06014515, the US trial registry maintained by the National Library of Medicine. NCT06014515 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.