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NCT05459961 · ClinicalTrials.gov registry record · NA
Metabolic Responses to Spermidine Supplementation.
A NA study of Healthy Subjects, sponsored by Chrysea Labs Lda.
- Active
- Registry status
- NA
- Development phase
- 42
- Enrollment target
- 1
- Study location
NCT05459961: Active NA study of Healthy Subjects, sponsored by Chrysea Labs Lda.
NCT05459961 is a NA study of Healthy Subjects that is active but no longer recruiting, run by Chrysea Labs Lda. The registered enrollment target is 42 participants, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05459961, a NA study of Healthy Subjects, is active but no longer recruiting, sponsored by Chrysea Labs Lda.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
- 1
- Study location
Study Summary
Spermidine is naturally present in cells, organs, circulating cardiovascular system, and as part of our normal dietary intake. Studies suggest Spermidine is involved in antioxidation, autophagy, apoptosis, and immune regulation. Spermidine is typically present in foods of plant origin, such as natto, beans, fruits, vegetables, cheese, potatoes, bread, and cereals. Adequate spermidine dietary intake is important, given evidence of declining spermidine levels with age in humans and other species, and the evidence for positive effects of spermidine supplementation on age related biology. To date, human research studies utilised extracts containing low levels of spermidine (\< 10%) and multiple other constituents, but this study will use pure spermidine to explore relevant mechanisms of action, biological effects, and identify potential biomarkers of positive biological effects.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT oral spermidine
Study Locations (1)
Illinois
- Biofortis Innovation Services - Addison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2022-08-14 |
| Est. Completion | 2025-02 |
| Phase | NA |
What the registry record for NCT05459961 still lists
NCT05459961 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Healthy Subjects appearing as the primary indexed condition, and to 1 intervention - of which oral spermidine is the first listed.
NCT05459961 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05459961 about?
NCT05459961 is a clinical study titled "Metabolic Responses to Spermidine Supplementation.". Spermidine is naturally present in cells, organs, circulating cardiovascular system, and as part of our normal dietary intake. Studies suggest Spermidine is involved in antioxidation, autophagy, apoptosis, and immune regulation. Spermidine is typically present in foods of plant origin, such as natto...
What is the current status of trial NCT05459961?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 42 participants. The study started on 2022-08-14. Estimated completion is 2025-02.
What conditions does trial NCT05459961 study?
This clinical trial studies the following conditions: Healthy Subjects.
What interventions are being tested in trial NCT05459961?
The interventions under investigation include: oral spermidine (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05459961?
This trial is sponsored by Chrysea Labs Lda, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05459961 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05459961's enrollment target sits among peer trials
42 29th of 69 higher than 41 of 69 other Healthy Subjects trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Subjects trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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