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ClinicalTrials.gov 89 recruiting now official registry

Head and Neck Cancer clinical trials

89 of 260 indexed Head and Neck Cancer trials are currently recruiting.

260 US clinical trials · 89 currently recruiting

Head and Neck Cancer is the subject of 260 registered US clinical trials on ClinicalTrials.gov, 89 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 137 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 19 of these trials.

The research picture

Head and Neck Cancer has 260 registered US clinical trials, 89 of them open to new participants right now, about 34% of the total.

89
recruiting participants now
34%
of trials open to enrollment
13
in Phase 3–4 (later-stage)
19
top sponsor: M.D. Anderson Cancer Center
Phase 163Phase 274Phase 311Phase 42

Active & Recent Trials

260 total, page 6 of 6

COMPLETED Phase 1 1 participants

Cytochlor and Tetrahydrouridine as Radiosensitizers and Cisplatin Combined With Radiation Therapy in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity (Mouth) or Oropharynx (Throat)

University of Miami

NCT00077051

COMPLETED Phase 2

Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer

Eastern Cooperative Oncology Group

NCT00040807

COMPLETED Phase 2

Oxaliplatin in Treating Patients With Advanced Head and Neck Cancer

Ohio State University Comprehensive Cancer Center

NCT00005035

COMPLETED Phase 2

Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer

National Cancer Institute (NCI)

NCT00004089

COMPLETED Phase 2

Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Stage III or Stage IV Head and Neck Cancer

Memorial Sloan Kettering Cancer Center

NCT00005814

COMPLETED Phase 3

Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

Eastern Cooperative Oncology Group

NCT00002888

COMPLETED Phase 3

Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer

Radiation Therapy Oncology Group

NCT00006481

COMPLETED Phase 2

Bryostatin 1 in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Memorial Sloan Kettering Cancer Center

NCT00003443

COMPLETED

Study of Proteins in Head and Neck Cancer Cells

Vanderbilt University Medical Center

NCT00896948

COMPLETED NA

Fluorescent Light Bronchoscopy Plus White Light Bronchoscopy for Early Detection of Lung Cancer

National Cancer Institute (NCI)

NCT00019201

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Phase Distribution

PhaseTrial count
Phase 1 63
Phase 2 74
Phase 3 11
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Head and Neck Cancer Trial Landscape

260 indexed Head and Neck Cancer studies · 89 recruiting (34%).

Phase mix: 13 late (III/IV) vs 137 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (19 trials), 9 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Head and Neck Cancer?

PlainTrial tracks 260 US clinical trials for Head and Neck Cancer, of which 89 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Head and Neck Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.