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Head and Neck Cancer: early-phase trial registry
89 of 260 indexed Head and Neck Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #39 of 28,707 conditions by registered trial count.
260 US clinical trials · 89 currently recruiting · #39 of 28,707 conditions by registered trial count
Head and Neck Cancer: 260 US clinical trials tracked, 89 recruiting.
Head and Neck Cancer is the subject of 260 registered US clinical trials on ClinicalTrials.gov, 89 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 137 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 19 of these trials.
Enrollment posture brief
Registry condition head-and-neck-cancer
OPEN 89 | RECR 34% | LATE 13 | EARLY 137 | RANK #39 | SPON 19
Volume-matched condition peers
Nearest open-share peer: Recurrent Malignant Solid Neoplasm (34% recruiting · 38 trials)
Head and Neck Cancer lists 89 open slots (34% of 260 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Head and Neck Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Head and Neck Cancer is recruiting below its size-band peers.
89 of 260 indexed trials (34.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Head and Neck Cancer trials is spread across many organizations.
M.D. Anderson Cancer Center accounts for 19 of 260 trials (7.3%). 124 distinct sponsors appear on at least one study for this condition label.
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Most Head and Neck Cancer trials plan to enrol fewer than 100 people.
Median target enrolment is 53 among the 251 trials that report a genuine target (sentinel values excluded). 165 of those (65.7%) plan for fewer than 100 participants.
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Head and Neck Cancer research is mostly interventional.
213 interventional and 47 observational studies make up this index (81.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
260 total, page 6 of 6
Cytochlor and Tetrahydrouridine as Radiosensitizers and Cisplatin Combined With Radiation Therapy in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity (Mouth) or Oropharynx (Throat)
University of Miami
NCT00077051
Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer
Eastern Cooperative Oncology Group
NCT00040807
Oxaliplatin in Treating Patients With Advanced Head and Neck Cancer
Ohio State University Comprehensive Cancer Center
NCT00005035
Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer
National Cancer Institute (NCI)
NCT00004089
Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Stage III or Stage IV Head and Neck Cancer
Memorial Sloan Kettering Cancer Center
NCT00005814
Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer
Eastern Cooperative Oncology Group
NCT00002888
Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer
Radiation Therapy Oncology Group
NCT00006481
Bryostatin 1 in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
Memorial Sloan Kettering Cancer Center
NCT00003443
Study of Proteins in Head and Neck Cancer Cells
Vanderbilt University Medical Center
NCT00896948
Fluorescent Light Bronchoscopy Plus White Light Bronchoscopy for Early Detection of Lung Cancer
National Cancer Institute (NCI)
NCT00019201
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 63 |
| Phase 2 | 74 |
| Phase 3 | 11 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Head and Neck Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Head and Neck Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Head and Neck Cancer page
260 registered trials, 89 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 89 Head and Neck Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Head and Neck Cancer trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Head and Neck Cancer condition card totals 260 registered trials; most-linked intervention cisplatin; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.