Radiation Therapy Oncology Group

Closed portfolio snapshot

According to ClinicalTrials.gov-derived indexes, Radiation Therapy Oncology Group sits in the top decile of US sponsors by registered trial count (#196 of 15,742 sponsors by registered trial count).

144 total trials none currently recruiting 131 completed top decile by trial count

Radiation Therapy Oncology Group: 144 sponsored US clinical trials, none currently recruiting.

Radiation Therapy Oncology Group sponsors 144 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 131 completed. 55 of these trials are in Phase 3-4 (later-stage) and 82 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 10 trials.

Top-decile sponsor footprint

Radiation Therapy Oncology Group ranks in the top decile of sponsors by registered trial count (#196 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 77/100

131 of 138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (94.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

144 total, page 1 of 3

ACTIVE NOT RECRUITING Phase 3

Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer

NCT01993810

ACTIVE NOT RECRUITING Phase 3

Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

NCT01368588

ACTIVE NOT RECRUITING Phase 3

Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery

NCT01349322

ACTIVE NOT RECRUITING Phase 2

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

NCT01220583

ACTIVE NOT RECRUITING Phase 3

RT With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer

NCT00956007

ACTIVE NOT RECRUITING Phase 3

Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer

NCT00567580

TERMINATED Phase 2

High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery

NCT01921751

COMPLETED Phase 3

Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer

NCT01730937

COMPLETED Phase 2

TRYHARD: Radiation Therapy Plus Cisplatin With or Without Lapatinib in Treating Patients With Head and Neck Cancer.

NCT01711658

COMPLETED Phase 2

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

NCT01730950

COMPLETED Phase 3

Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer

NCT01672892

COMPLETED Phase 3

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

NCT01546987

COMPLETED Phase 1

Ganitumab and Gemcitabine Hydrochloride Followed by Radiation Therapy, Ganitumab, Capecitabine, and Maintenance Therapy in Treating Patients With Locally Advanced Cancer of the Pancreas

NCT01298401

COMPLETED Phase 2

Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer

NCT01262560

COMPLETED

Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery

NCT01417507

COMPLETED Phase 2

Radiation Therapy in Treating Patients With Prostate Cancer

NCT01434290

COMPLETED Phase 2

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

NCT01399372

COMPLETED Phase 3

Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer

NCT01302834

COMPLETED Phase 2

Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

NCT01227954

COMPLETED Phase 2

Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer

NCT00979212

COMPLETED Phase 1

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT01062399

COMPLETED Phase 1

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

NCT01026493

COMPLETED Phase 2

Radiation Therapy in Treating Women With Locally Recurrent Breast Cancer Previously Treated With Repeat Breast-Preserving Surgery

NCT01082211

COMPLETED Phase 2

Radiation Therapy in Treating Patients With Extensive Stage Small Cell Lung Cancer

NCT01055197

COMPLETED Phase 3

Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy

NCT00931528

COMPLETED Phase 2

Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

NCT00960999

COMPLETED Phase 2

Radiation Therapy and Chemotherapy in Treating Patients With Stage I Bladder Cancer

NCT00981656

COMPLETED Phase 2

Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis

NCT00922974

COMPLETED Phase 3

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

NCT00936390

COMPLETED Phase 3

Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy

NCT00980954

COMPLETED Phase 2

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

NCT00895622

COMPLETED

Depression Screening in Patients Undergoing Radiation Therapy For Cancer

NCT00951184

COMPLETED Phase 1

Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

NCT00750269

COMPLETED Phase 2

Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery

NCT00777491

TERMINATED Phase 2

Chemotherapy and Radiation Therapy (RT) With or Without Vandetanib in Treating Patients With High-Risk Stage III or Stage IV Head and Neck Cancer

NCT00720083

COMPLETED Phase 2

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

NCT00656513

COMPLETED Phase 3

Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer

NCT00655876

COMPLETED Phase 2

Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy

NCT00528866

COMPLETED Phase 2

Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer

NCT00613080

COMPLETED Phase 2

Samarium Sm 153 Lexidronam Pentasodium and 3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Rising Prostate-Specific Antigen Levels After Radical Prostatectomy for Prostate Cancer

NCT00551525

COMPLETED Phase 2

Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg

NCT00589121

COMPLETED Phase 3

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

NCT00566852

COMPLETED Phase 2

G-CSF and Pegfilgrastim in Treating Neutropenia in Patients Undergoing Radiation Therapy and Chemotherapy for Limited Stage Small Cell Lung Cancer

NCT00554463

COMPLETED Phase 2

Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed By Surgery

NCT00551369

COMPLETED Phase 3

High-Dose or Standard-Dose Radiation Therapy and Chemotherapy With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

NCT00533949

COMPLETED Phase 2

Ultrasound-Guided Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer Previously Treated With External-Beam Radiation Therapy

NCT00450411

COMPLETED Phase 2

Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer

NCT00423293

COMPLETED Phase 3

Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer

NCT00365105

TERMINATED Phase 3

Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck Cancer

NCT00360971

COMPLETED

Changes in DNA After Radiation Therapy in Patients With Prostate Cancer

NCT00899912

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How the Radiation Therapy Oncology Group archive is shaped

144 indexed studies, none listed as recruiting (0% open); 131 completed (91%).

Phase mix: 55 late (III/IV) vs 82 early (I/II) (balanced across stages).

Top condition: Prostate Cancer (10 trials), 9 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Radiation Therapy Oncology Group: archived-pipeline peers nationwide

Peers matched on 144 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Radiation Therapy Oncology Group sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200 0%5%10%15% Total trials Recruiting share Radiation Therapy Oncology GroupForest LaboratoriesNational Institute of Environmental Health Sciences (NIEHS)HealthPartners InstituteMylan Pharmaceuticals10xBio22nd Century Group23andMe3-C Institute for Social Development
Radiation Therapy Oncology Group sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Radiation Therapy Oncology Group sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 144 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Radiation Therapy Oncology Group page

144 registered trials is a research-attention snapshot, not an endorsement of Radiation Therapy Oncology Group or any single study.

  • None of Radiation Therapy Oncology Group's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Prostate Cancer is the condition Radiation Therapy Oncology Group studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Radiation Therapy Oncology Group pipeline card: 144 registered trials from official public datasets.Report a data error.