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NCT00006481 · ClinicalTrials.gov registry record · Phase 3

Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer

A Phase 3 study of Head and Neck Cancer and Skin Reactions Secondary to Radiation Therapy, sponsored by Radiation Therapy Oncology Group.

Completed
Registry status
Phase 3
Development phase
20
Study locations

NCT00006481 is a Phase 3 study of Head and Neck Cancer and Skin Reactions Secondary to Radiation Therapy that has completed, run by Radiation Therapy Oncology Group. The trial reports 20 study locations across 5 states.

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The verdict

NCT00006481, a Phase 3 study of Head and Neck Cancer and Skin Reactions Secondary to Radiation Therapy, has completed, sponsored by Radiation Therapy Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
20
Study locations

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells, but may cause skin irritation and inflammation. Biafine cream may be effective in lessening side effects caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of Biafine cream in reducing side effects of radiation therapy in patients receiving treatment for head and neck cancer.

Interventions

  • PROCEDURE quality-of-life assessment
  • RADIATION radiation therapy
  • DRUG Biafine cream

Study Locations (20)

California

  • Mount Diablo Medical Center - Concord
  • Cancer Center and Beckman Research Institute, City of Hope - Duarte
  • California Cancer Center - Fresno
  • Saint Agnes Cancer Center - Fresno
  • Glendale Memorial Hospital and Health Center - Glendale
  • Sutter Health West Cancer Research Group - Greenbrae
  • University of California San Diego Cancer Center - La Jolla
  • Loma Linda University Medical Center - Loma Linda
  • Veterans Affairs Medical Center - Long Beach - Long Beach
  • USC/Norris Comprehensive Cancer Center and Hospital - Los Angeles

Alabama

  • University of Alabama at Birmingham Comprehensive Cancer Center - Birmingham
  • Huntsville Hospital System - Huntsville
  • Comprehensive Cancer Institute of Huntsville - Huntsville
  • MBCCOP - Gulf Coast - Mobile
  • Alabama Oncology, LLC - Montgomery
  • Radiation Oncology Associates of West Alabama - Tuscaloosa

Arizona

  • Foundation for Cancer Research and Education - Phoenix
  • Arizona Cancer Center - Tucson

Alaska

  • Providence Alaska Medical Center - Anchorage

Arkansas

  • University of Arkansas for Medical Sciences - Little Rock

Trial Details

FieldValue
Start Date 2000-10
Phase Phase 3

Sponsor

Radiation Therapy Oncology Group

144 total trials

What the Registry Record Tells You About NCT00006481

The ClinicalTrials.gov registry entry for NCT00006481 describes a study currently listed as completed, categorized as Phase 3. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Radiation Therapy Oncology Group, which has 144 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 3 interventions - of which quality-of-life assessment is the first listed.

NCT00006481 reports 20 study locations spanning 5 distinct geographic areas - top geographies include California, Alabama, Arizona.

Frequently Asked Questions

What is clinical trial NCT00006481 about?

NCT00006481 is a clinical study titled "Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells, but may cause skin irritation and inflammation. Biafine cream may be effective in lessening side effects caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of Biafine cream in re...

What is the current status of trial NCT00006481?

This trial is currently completed. It is a Phase 3 study. The study started on 2000-10.

What conditions does trial NCT00006481 study?

This clinical trial studies the following conditions: Head and Neck Cancer, Skin Reactions Secondary to Radiation Therapy.

What interventions are being tested in trial NCT00006481?

The interventions under investigation include: quality-of-life assessment (PROCEDURE), radiation therapy (RADIATION), Biafine cream (DRUG).

Who is sponsoring clinical trial NCT00006481?

This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00006481 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.