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NCT00002888 · ClinicalTrials.gov registry record · Phase 3

Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

A Phase 3 study of Head and Neck Cancer, sponsored by Eastern Cooperative Oncology Group.

Completed
Registry status
Phase 3
Development phase
20
Study locations

NCT00002888 is a Phase 3 study of Head and Neck Cancer that has completed, run by Eastern Cooperative Oncology Group. The trial reports 20 study locations across 5 states.

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The verdict

NCT00002888, a Phase 3 study of Head and Neck Cancer, has completed, sponsored by Eastern Cooperative Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
20
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether cisplatin plus fluorouracil are more effective than paclitaxel plus cisplatin in treating patients with advanced head and neck cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients with advanced head and neck cancer.

Conditions Studied

Head and Neck Cancer

Interventions

  • DRUG cisplatin
  • DRUG paclitaxel
  • DRUG fluorouracil

Study Locations (20)

California

  • Beckman Research Institute, City of Hope - Duarte
  • Veterans Affairs Medical Center - Long Beach - Long Beach
  • USC/Norris Comprehensive Cancer Center - Los Angeles
  • Jonsson Comprehensive Cancer Center, UCLA - Los Angeles
  • Veterans Affairs Outpatient Clinic - Martinez - Martinez
  • CCOP - Bay Area Tumor Institute - Oakland
  • Chao Family Comprehensive Cancer Center - Orange
  • University of California Davis Medical Center - Sacramento
  • UCSF Cancer Center and Cancer Research Institute - San Francisco
  • CCOP - Santa Rosa Memorial Hospital - Santa Rosa
  • David Grant Medical Center - Travis Air Force Base

Arizona

  • CCOP - Greater Phoenix - Phoenix
  • Veterans Affairs Medical Center - Phoenix (Hayden) - Phoenix
  • Veterans Affairs Medical Center - Tucson - Tucson
  • Arizona Cancer Center - Tucson

Arkansas

  • University of Arkansas for Medical Sciences - Little Rock
  • Veterans Affairs Medical Center - Little Rock (McClellan) - Little Rock

Colorado

  • Veterans Affairs Medical Center - Denver - Denver
  • University of Colorado Cancer Center - Denver

Alabama

  • MBCCOP - University of South Alabama - Mobile

Trial Details

FieldValue
Start Date 1997-03
Est. Completion 2004-08
Phase Phase 3

Sponsor

Eastern Cooperative Oncology Group

141 total trials

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What the Registry Record Tells You About NCT00002888

The ClinicalTrials.gov registry entry for NCT00002888 describes a study currently listed as completed, categorized as Phase 3. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Eastern Cooperative Oncology Group, which has 141 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Head and Neck Cancer appearing as the primary indexed condition, and to 3 interventions - of which cisplatin is the first listed.

NCT00002888 reports 20 study locations spanning 5 distinct geographic areas - top geographies include California, Arizona, Arkansas.

Frequently Asked Questions

What is clinical trial NCT00002888 about?

NCT00002888 is a clinical study titled "Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether cisplatin plus fluorouracil are more effective than paclitaxel plus cisplatin in treating patien...

What is the current status of trial NCT00002888?

This trial is currently completed. It is a Phase 3 study. The study started on 1997-03. Estimated completion is 2004-08.

What conditions does trial NCT00002888 study?

This clinical trial studies the following conditions: Head and Neck Cancer.

What interventions are being tested in trial NCT00002888?

The interventions under investigation include: cisplatin (DRUG), paclitaxel (DRUG), fluorouracil (DRUG).

Who is sponsoring clinical trial NCT00002888?

This trial is sponsored by Eastern Cooperative Oncology Group, which has 141 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00002888 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.