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Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque
NCT04921371 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a positive control mouth rinse and a hydroalcohol control mouth rinse for the reduction of gingivitis and plaque when used as an adjunct to tooth brushing during a six-week product usage period.
Conditions Studied
Interventions
- OTHER Colgate® Cavity Protection Toothpaste
- OTHER Listerine® Cool Mint®
- OTHER Concept Curve Winter Series Toothbrush
- OTHER 5% Hydroalcohol Mouthrinse
- OTHER Mouthrinse Prototype 1
Study Locations (1)
Indiana
- Salus Research, Inc. — Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 157 participants |
| Start Date | 2019-10-08 |
| Est. Completion | 2019-12-19 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04921371
The ClinicalTrials.gov registry entry for NCT04921371 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 157 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johnson & Johnson Consumer Inc. (J&JCI), which has 12 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Gingivitis appearing as the primary indexed condition, and to 5 interventions — of which Colgate® Cavity Protection Toothpaste is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04921371 reports 1 study location spanning 1 distinct geographic area — top geographies include Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04921371 about?
NCT04921371 is a clinical study titled "Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque". The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a positive control mouth rinse and a hydroalcohol control mouth rinse for the reduction of gingivitis and plaque when used as an adjunct to tooth brushing during a six-week product u...
What is the current status of trial NCT04921371?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 157 participants. The study started on 2019-10-08. Estimated completion is 2019-12-19.
What conditions does trial NCT04921371 study?
This clinical trial studies the following conditions: Gingivitis, Plaque. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04921371?
The interventions under investigation include: Colgate® Cavity Protection Toothpaste (OTHER), Listerine® Cool Mint® (OTHER), Concept Curve Winter Series Toothbrush (OTHER), 5% Hydroalcohol Mouthrinse (OTHER), Mouthrinse Prototype 1 (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04921371?
This trial is sponsored by Johnson & Johnson Consumer Inc. (J&JCI), which has 12 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04921371 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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