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NCT02750943 · ClinicalTrials.gov registry record · NA
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
A NA study of Gingivitis, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- NA
- Development phase
- 253
- Enrollment target
- 1
- Study location
NCT02750943: Completed NA study of Gingivitis, sponsored by GlaxoSmithKline.
NCT02750943 is a NA study of Gingivitis that has completed, run by GlaxoSmithKline. The registered enrollment target is 253 participants, above the 227-participant average among 25 other Gingivitis trials with a reported enrollment target (11% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02750943, a NA study of Gingivitis, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- NA
- Development phase
- 253 participants
- Enrollment target
- 1
- Study location
Study Summary
This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis. This study will evaluate the efficacy of a dentifrice containing 0.454% weight by weight (w/w) stannous fluoride to control gingivitis and gingival bleeding following 12 weeks twice daily brushing, compared to a negative control dentifrice.
Primary Outcome
Number of bleeding sites was measured as bleeding index (BI) via a single examiner using a color coded periodontal probe. The probe was engaged approximately 1 millimetre (mm) into the gingival crevice. A moderate pressure was used whilst sweeping from interproximal to interproximal along the sulcular epithelium. The BI was assessed on the facial and lingual gingival surfaces of each scorable tooth (7-7 in each arch). The BI scoring system used to measure bleeding sites is as follows: 0= No blee
Conditions Studied
Interventions
- DRUG Stannous Fluoride
- DRUG Sodium Monofluorophosphate
Study Locations (1)
Nevada
- GSK Investigational Site - Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 253 participants |
| Start Date | 2015-11-01 |
| Est. Completion | 2016-03-04 |
| Phase | NA |
What the finished NCT02750943 record still lists
NCT02750943 is an interventional study that assigns participants to a tested intervention. The registered 253 participants enrollment target is mid-sized for trials with a published cap, above the 227-participant average among 25 other Gingivitis trials with a reported enrollment target (11% higher).
The record links to 1 condition, with Gingivitis appearing as the primary indexed condition, and to 2 interventions - of which Stannous Fluoride is the first listed.
NCT02750943 reports a single indexed study location in Nevada.
Frequently Asked Questions
What is clinical trial NCT02750943 about?
NCT02750943 is a clinical study titled "Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease". This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis. This study will evaluate the efficacy of a dentifrice containing 0.454% ...
What is the current status of trial NCT02750943?
This trial is currently completed. It is a NA study. The enrollment target is 253 participants. The study started on 2015-11-01. Estimated completion is 2016-03-04.
What conditions does trial NCT02750943 study?
This clinical trial studies the following conditions: Gingivitis.
What interventions are being tested in trial NCT02750943?
The interventions under investigation include: Stannous Fluoride (DRUG), Sodium Monofluorophosphate (DRUG).
Who is sponsoring clinical trial NCT02750943?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02750943 being conducted?
This trial has 1 study location across Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gingivitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02750943's enrollment target sits among peer trials
253 4th of 25 higher than 22 of 25 other Gingivitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gingivitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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