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NCT06933368 · ClinicalTrials.gov registry record · NA
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
A NA study of Gingivitis and Dental Plaque, sponsored by HALEON.
- Completed
- Registry status
- NA
- Development phase
- 136
- Enrollment target
- 1
- Study location
NCT06933368: Completed NA study of Gingivitis and Dental Plaque, sponsored by HALEON.
NCT06933368 is a NA study of Gingivitis and Dental Plaque that has completed, run by HALEON. The registered enrollment target is 136 participants, below the 231-participant average among 25 other Gingivitis trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06933368, a NA study of Gingivitis and Dental Plaque, has completed, sponsored by HALEON.
- COMPLETED
- Registry status
- NA
- Development phase
- 136 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this 12-week clinical study is to evaluate the ability of an experimental mouthwash, containing 0.085 percent (%) Cetylpyridinium chloride (CPC) as an adjunct to toothbrushing with a regular fluoride toothpaste, to improve gingival health and plaque accumulation compared to a regular fluoride toothpaste alone in participants with plaque-induced mild to moderate gingivitis.
Primary Outcome
Gingival bleeding will be assessed according to the expanded bleeding index (EBI), by inserting a periodontal probe into the gingival crevice and sweeping from distal to mesial around the tooth at an approximate angle of 60 degree, while in contact with the sulcular epithelium. Each of six gingival areas (distobuccal, midbuccal, mesiobuccal, distolingual, midlingual, and mesiolingual) around each tooth will be assessed. All scorable teeth in one quadrant will be probed first (approximately 30 se
Conditions Studied
Interventions
- DRUG Crest Cavity Protection Toothpaste
- DRUG Experimental Mouthwash
Study Locations (1)
Indiana
- Salus Research Inc - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 136 participants |
| Start Date | 2025-04-21 |
| Est. Completion | 2025-08-14 |
| Phase | NA |
What the finished NCT06933368 record still lists
NCT06933368 is an interventional study that assigns participants to a tested intervention. The registered 136 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 25 other Gingivitis trials with a reported enrollment target (41% lower).
The record links to 2 conditions, with Gingivitis appearing as the primary indexed condition, and to 2 interventions - of which Crest Cavity Protection Toothpaste is the first listed.
NCT06933368 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT06933368 about?
NCT06933368 is a clinical study titled "A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation". The aim of this 12-week clinical study is to evaluate the ability of an experimental mouthwash, containing 0.085 percent (%) Cetylpyridinium chloride (CPC) as an adjunct to toothbrushing with a regular fluoride toothpaste, to improve gingival health and plaque accumulation compared to a regular fluo...
What is the current status of trial NCT06933368?
This trial is currently completed. It is a NA study. The enrollment target is 136 participants. The study started on 2025-04-21. Estimated completion is 2025-08-14.
What conditions does trial NCT06933368 study?
This clinical trial studies the following conditions: Gingivitis, Dental Plaque.
What interventions are being tested in trial NCT06933368?
The interventions under investigation include: Crest Cavity Protection Toothpaste (DRUG), Experimental Mouthwash (DRUG).
Who is sponsoring clinical trial NCT06933368?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06933368 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06933368's enrollment target sits among peer trials
136 10th of 25 higher than 16 of 25 other Gingivitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gingivitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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