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NCT06660069 · ClinicalTrials.gov registry record · NA
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
A NA study of Gingivitis and Dental Plaque, sponsored by HALEON.
- Completed
- Registry status
- NA
- Development phase
- 199
- Enrollment target
- 1
- Study location
NCT06660069: Completed NA study of Gingivitis and Dental Plaque, sponsored by HALEON.
NCT06660069 is a NA study of Gingivitis and Dental Plaque that has completed, run by HALEON. The registered enrollment target is 199 participants, below the 229-participant average among 25 other Gingivitis trials with a reported enrollment target (13% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06660069, a NA study of Gingivitis and Dental Plaque, has completed, sponsored by HALEON.
- COMPLETED
- Registry status
- NA
- Development phase
- 199 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation, compared to the use of a regular fluoride toothpaste alone in participants with clinically measurable plaque-induced gingivitis.
Primary Outcome
Gingival bleeding was assessed according to the expanded bleeding index (EBI), by inserting a periodontal probe into the gingival crevice and sweeping from distal to mesial around the tooth at an approximate angle of 60 degrees, while in contact with the sulcular epithelium. Each of six gingival areas (distobuccal, midbuccal, mesiobuccal, distolingual, midlingual, and mesiolingual) around each tooth were assessed. Presence/absence of gingival bleeding was assessed for 30 seconds after probing. T
Conditions Studied
Interventions
- DRUG Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste)
- DRUG CPC Mouthwash (Parodontax Active Gum Health Mouthwash)
- DRUG Regular Fluoride Toothpaste (Crest Cavity Protection)
Study Locations (1)
Indiana
- Salus Research - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 199 participants |
| Start Date | 2024-11-18 |
| Est. Completion | 2025-03-11 |
| Phase | NA |
What the finished NCT06660069 record still lists
NCT06660069 is an interventional study that assigns participants to a tested intervention. The registered 199 participants enrollment target is mid-sized for trials with a published cap, below the 229-participant average among 25 other Gingivitis trials with a reported enrollment target (13% lower).
The record links to 2 conditions, with Gingivitis appearing as the primary indexed condition, and to 3 interventions - of which Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste) is the first listed.
NCT06660069 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT06660069 about?
NCT06660069 is a clinical study titled "A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation". The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation, compared to the use of a regular fluoride toothpaste alone in participants wit...
What is the current status of trial NCT06660069?
This trial is currently completed. It is a NA study. The enrollment target is 199 participants. The study started on 2024-11-18. Estimated completion is 2025-03-11.
What conditions does trial NCT06660069 study?
This clinical trial studies the following conditions: Gingivitis, Dental Plaque.
What interventions are being tested in trial NCT06660069?
The interventions under investigation include: Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste) (DRUG), CPC Mouthwash (Parodontax Active Gum Health Mouthwash) (DRUG), Regular Fluoride Toothpaste (Crest Cavity Protection) (DRUG).
Who is sponsoring clinical trial NCT06660069?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06660069 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06660069's enrollment target sits among peer trials
199 5th of 25 higher than 21 of 25 other Gingivitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gingivitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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