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Assessing Gingivitis and Plaque From a Marketed Toothpaste
NCT07158112 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to evaluate the effect of two 0.454% stannous fluoride dentifrices on gingivitis relative to a negative control (Colgate® Cavity Protection toothpaste) and the comparative anti-gingivitis efficacy of the two 0.454% SnF2 dentifrices after 12 weeks of product use.
Conditions Studied
Interventions
- DRUG Stannous Fluoride Dentifrice
- DRUG Test Stannous Fluoride Dentifrice
- DRUG Sodium monofluorophosphate dentifrice
Study Locations (1)
California
- University Health Resources Group — Whitter
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-08-30 |
| Est. Completion | 2025-12-07 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07158112
The ClinicalTrials.gov registry entry for NCT07158112 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Procter and Gamble, which has 25 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Gingivitis appearing as the primary indexed condition, and to 3 interventions — of which Stannous Fluoride Dentifrice is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07158112 reports 1 study location spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07158112 about?
NCT07158112 is a clinical study titled "Assessing Gingivitis and Plaque From a Marketed Toothpaste". The primary objective of this study is to evaluate the effect of two 0.454% stannous fluoride dentifrices on gingivitis relative to a negative control (Colgate® Cavity Protection toothpaste) and the comparative anti-gingivitis efficacy of the two 0.454% SnF2 dentifrices after 12 weeks of product use...
What is the current status of trial NCT07158112?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2025-08-30. Estimated completion is 2025-12-07.
What conditions does trial NCT07158112 study?
This clinical trial studies the following conditions: Gingivitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07158112?
The interventions under investigation include: Stannous Fluoride Dentifrice (DRUG), Test Stannous Fluoride Dentifrice (DRUG), Sodium monofluorophosphate dentifrice (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07158112?
This trial is sponsored by Procter and Gamble, which has 25 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07158112 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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