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NCT07255040 · ClinicalTrials.gov registry record · NA
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
A NA study of Gingivitis and Dental Plaque, sponsored by HALEON.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 1
- Study location
NCT07255040: Recruiting NA study of Gingivitis and Dental Plaque, sponsored by HALEON.
NCT07255040 is a NA study of Gingivitis and Dental Plaque that is actively recruiting participants, run by HALEON. The registered enrollment target is 300 participants, above the 225-participant average among 25 other Gingivitis trials with a reported enrollment target (33% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07255040, a NA study of Gingivitis and Dental Plaque, is actively recruiting participants, sponsored by HALEON.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and prevention of plaque accumulation compared with a regular fluoride dentifrice (negative control) in participants with mild to moderate gingivitis.
Primary Outcome
Number of bleeding sites will be assessed using the bleeding index (BI) assessment. BI will be assessed for all evaluable surfaces of the facial and lingual/palatal gingiva, six sites per tooth. The probe will be inserted approximately 1 millimeter (mm) into the gingival sulcus and moved around the tooth from the distal interproximal area to the mesial interproximal area, gently stretching the gingival epithelium. The number of bleeding sites for each participant will be calculated as the number
Conditions Studied
Interventions
- DRUG Test Dentifrice
- DRUG Parodontax Complete Protection
- DRUG Colgate Cavity Protection
Study Locations (1)
Indiana
- Salus Research, Inc. - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2025-11-19 |
| Est. Completion | 2026-07 |
| Phase | NA |
What NCT07255040 shows while recruiting
NCT07255040 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 225-participant average among 25 other Gingivitis trials with a reported enrollment target (33% higher).
The record links to 2 conditions, with Gingivitis appearing as the primary indexed condition, and to 3 interventions - of which Test Dentifrice is the first listed.
NCT07255040 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT07255040 about?
NCT07255040 is a clinical study titled "A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation". The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and prevention of plaque accumulation compared with a regular fluoride dentifrice...
What is the current status of trial NCT07255040?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2025-11-19. Estimated completion is 2026-07.
What conditions does trial NCT07255040 study?
This clinical trial studies the following conditions: Gingivitis, Dental Plaque.
What interventions are being tested in trial NCT07255040?
The interventions under investigation include: Test Dentifrice (DRUG), Parodontax Complete Protection (DRUG), Colgate Cavity Protection (DRUG).
Who is sponsoring clinical trial NCT07255040?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07255040 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gingivitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07255040's enrollment target sits among peer trials
300 2nd of 25 the highest of 25 other Gingivitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gingivitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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