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NCT05468255 · ClinicalTrials.gov registry record · NA

The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults

A NA study of Exercise and Glucose Intolerance, sponsored by Old Dominion University.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT05468255: Recruiting NA study of Exercise and Glucose Intolerance, sponsored by Old Dominion University.

NCT05468255 is a NA study of Exercise and Glucose Intolerance that is actively recruiting participants, run by Old Dominion University. The registered enrollment target is 40 participants, below the 8,910-participant average among 57 other Exercise trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05468255, a NA study of Exercise and Glucose Intolerance, is actively recruiting participants, sponsored by Old Dominion University.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consumption of a meal. It is an indicator of insulin resistance (or type 2 diabetes) and impaired glycemic control has been suggested to lead to cardiovascular disease. Endothelial function has been shown to be improved by chronic or acute increases in physical activity. Both of these have been shown to be impaired to acute bouts of inactivity in young populations; however the impact of acute inactivity in older adults is less understood. In this proposal the investigators will examine 1)how quickly impairments in glycemic control occur to acute physical inactivity in older adults who exercise, 2) how quickly impairments in endothelial function occur to acute inactivity in older adults who exercise, and 3) whether 3 days of a return to exercise restores these responses.

Interventions

  • OTHER removal of exercise

Study Locations (1)

Virginia

  • Old Dominion University - Norfolk

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2022-07-25
Est. Completion 2025-04-01
Phase NA
Old Dominion University

23 total trials

What NCT05468255 shows while recruiting

NCT05468255 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 8,910-participant average among 57 other Exercise trials with a reported enrollment target (100% lower).

The record links to 3 conditions, with Exercise appearing as the primary indexed condition, and to 1 intervention - of which removal of exercise is the first listed.

NCT05468255 reports a single indexed study location in Virginia.

Frequently Asked Questions

What is clinical trial NCT05468255 about?

NCT05468255 is a clinical study titled "The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults". The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consump...

What is the current status of trial NCT05468255?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2022-07-25. Estimated completion is 2025-04-01.

What conditions does trial NCT05468255 study?

This clinical trial studies the following conditions: Exercise, Glucose Intolerance, Vascular Function.

What interventions are being tested in trial NCT05468255?

The interventions under investigation include: removal of exercise (OTHER).

Who is sponsoring clinical trial NCT05468255?

This trial is sponsored by Old Dominion University, which has 23 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05468255 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Exercise

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05468255's enrollment target sits among peer trials

40 35th of 57 higher than 18 of 57 other Exercise trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Exercise trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05468255, the US trial registry maintained by the National Library of Medicine. NCT05468255 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.