Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06425939 · ClinicalTrials.gov registry record · NA
Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance
A NA study of Exercise and Heart Rate Variability, sponsored by PepsiCo Global R&D.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 2
- Study locations
NCT06425939: Recruiting NA study of Exercise and Heart Rate Variability, sponsored by PepsiCo Global R&D.
NCT06425939 is a NA study of Exercise and Heart Rate Variability that is actively recruiting participants, run by PepsiCo Global R&D. The registered enrollment target is 50 participants, below the 8,910-participant average among 57 other Exercise trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06425939, a NA study of Exercise and Heart Rate Variability, is actively recruiting participants, sponsored by PepsiCo Global R&D.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 2
- Study locations
Study Summary
Heart rate variability (HRV) is a measure of the variation in time between each heartbeat. It is an indirect and ubiquitous biomarker of performance readiness and recovery measured by most consumer-grade wearable fitness trackers. However, there is little documented on the relationship between HRV, training load, and performance measures in the Real-World. Whoop wrist-worn activity trackers have been validated against the gold-standard Electrocardiography (ECG) for HRV and HR measurements. Whoop leverages photoplethysmography (PPG) technology to continuously track (HR, HRV, respiratory rate, energy expenditure) and provides, daily, individual insights, trends, and coaching to improve strain, sleep, and recovery. Research has demonstrated that heart rate variability (HRV) guided training may be more optimal compared to predetermined training for aerobic exercise improvements. The purpose of this study is to assess the feasibility of providing personalized training recommendations based on HRV measured by a consumer-grade wearable (Whoop) in a real-world setting to better understand the HRV relationship with performance.
Primary Outcome
% HRmax (in minutes) measured by force plates
Conditions Studied
Interventions
- OTHER Force plate assessment
- DEVICE Whoop wrist band
Study Locations (2)
Illinois
- PepsiCo R&D, Gatorade Sports Science Institute - Chicago
Texas
- PepsiCo R&D, Gatorade Sports Science Institute - Frisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-05-08 |
| Est. Completion | 2024-09-30 |
| Phase | NA |
What NCT06425939 shows while recruiting
NCT06425939 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 8,910-participant average among 57 other Exercise trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Exercise appearing as the primary indexed condition, and to 2 interventions - of which Force plate assessment is the first listed.
NCT06425939 reports a single indexed study location in Illinois, Texas.
Frequently Asked Questions
What is clinical trial NCT06425939 about?
NCT06425939 is a clinical study titled "Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance". Heart rate variability (HRV) is a measure of the variation in time between each heartbeat. It is an indirect and ubiquitous biomarker of performance readiness and recovery measured by most consumer-grade wearable fitness trackers. However, there is little documented on the relationship between HRV,...
What is the current status of trial NCT06425939?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-05-08. Estimated completion is 2024-09-30.
What conditions does trial NCT06425939 study?
This clinical trial studies the following conditions: Exercise, Heart Rate Variability.
What interventions are being tested in trial NCT06425939?
The interventions under investigation include: Force plate assessment (OTHER), Whoop wrist band (DEVICE).
Who is sponsoring clinical trial NCT06425939?
This trial is sponsored by PepsiCo Global R&D, which has 47 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06425939 being conducted?
This trial has 2 study locations across Illinois, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Exercise
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06425939's enrollment target sits among peer trials
50 29th of 57 higher than 26 of 57 other Exercise trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Exercise trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Goal Setting to Promote Physical Activity Adherence in Midlife Adults
RECRUITING · NA
-
Better Lifestyle Counseling for African American Women During Pregnancy
RECRUITING · NA
-
Developing a Nutritional Supplement to Increase Collagen Synthesis in People
RECRUITING · NA
-
Postnatal Exercise to Activate Baby's Brown Fat
RECRUITING · NA
-
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
RECRUITING · NA
-
The VESPA Pilot Study
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI