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NCT04292535 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise
A Phase 2 study of Exercise and Insulin, sponsored by Michigan State University.
- Completed
- Registry status
- Phase 2
- Development phase
- 116
- Enrollment target
- 1
- Study location
NCT04292535: Completed Phase 2 study of Exercise and Insulin, sponsored by Michigan State University.
NCT04292535 is a Phase 2 study of Exercise and Insulin that has completed, run by Michigan State University. The registered enrollment target is 116 participants, below the 8,909-participant average among 57 other Exercise trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04292535, a Phase 2 study of Exercise and Insulin, has completed, sponsored by Michigan State University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 116 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine if physical activity engagement alters the dose-response profile and safety of administration of insulin into the intranasal mucosa.
Primary Outcome
The manifestation of any symptom that could be associated with alterations in blood glucose and side effects of intranasal insulin. Fewer symptoms would indicate a better outcome. Burning/tingling of the nose and watering/tearing of the eyes during the nasal spray were the most cited symptoms.
Interventions
- DRUG Placebo into the intranasal mucosa
- DRUG 20 IU NovoLog Insulin aspart into the intranasal mucosa
- DRUG 40 IU NovoLog Insulin aspart into the intranasal mucosa
- DRUG 60 IU NovoLog Insulin aspart into the intranasal mucosa
- DRUG 80 IU NovoLog Insulin aspart into the intranasal mucosa
Study Locations (1)
Michigan
- Department of Kinesiology - East Lansing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2018-06-15 |
| Est. Completion | 2020-02-20 |
| Phase | Phase 2 |
What the finished NCT04292535 record still lists
NCT04292535 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, below the 8,909-participant average among 57 other Exercise trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Exercise appearing as the primary indexed condition, and to 5 interventions - of which Placebo into the intranasal mucosa is the first listed.
NCT04292535 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT04292535 about?
NCT04292535 is a clinical study titled "Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise". To determine if physical activity engagement alters the dose-response profile and safety of administration of insulin into the intranasal mucosa.
What is the current status of trial NCT04292535?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 116 participants. The study started on 2018-06-15. Estimated completion is 2020-02-20.
What conditions does trial NCT04292535 study?
This clinical trial studies the following conditions: Exercise, Insulin.
What interventions are being tested in trial NCT04292535?
The interventions under investigation include: Placebo into the intranasal mucosa (DRUG), 20 IU NovoLog Insulin aspart into the intranasal mucosa (DRUG), 40 IU NovoLog Insulin aspart into the intranasal mucosa (DRUG), 60 IU NovoLog Insulin aspart into the intranasal mucosa (DRUG), 80 IU NovoLog Insulin aspart into the intranasal mucosa (DRUG).
Who is sponsoring clinical trial NCT04292535?
This trial is sponsored by Michigan State University, which has 120 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04292535 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Exercise
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04292535's enrollment target sits among peer trials
116 19th of 57 higher than 39 of 57 other Exercise trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Exercise trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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