Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 108 recruiting now official registry

Endometrial Cancer clinical trials

108 of 188 indexed Endometrial Cancer trials are currently recruiting.

188 US clinical trials · 108 currently recruiting

Endometrial Cancer is the subject of 188 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 118 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 17 of these trials.

The research picture

Endometrial Cancer has 188 registered US clinical trials, 108 of them open to new participants right now, about 57% of the total.

108
recruiting participants now
57%
of trials open to enrollment
15
in Phase 3–4 (later-stage)
17
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 174Phase 244Phase 314Phase 41

Active & Recent Trials

188 total, page 4 of 4

COMPLETED NA 204 participants

Lymph Node Mapping in Patients With Endometrial Cancer

Ohio State University Comprehensive Cancer Center

NCT01818739

COMPLETED NA 180 participants

A Study Assessing the Safety and Utility of PINPOINT® Near Infrared Fluorescence Imaging in the Identification of Lymph Nodes in Patients With Uterine and Cervical Malignancies Who Are Undergoing Lymph Node Mapping

Novadaq Technologies ULC, now a part of Stryker

NCT02209532

COMPLETED NA 155 participants

Scale Down for Endometrial Cancer

Washington University School of Medicine

NCT03169023

COMPLETED NA 151 participants

Intra-Operative Lymphatic Mapping in Patients With Invasive Carcinoma of the Cervix or Endometrial Carcinoma

Memorial Sloan Kettering Cancer Center

NCT00595725

COMPLETED Phase 1 149 participants

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Incyte Corporation

NCT03314935

COMPLETED NA 111 participants

FitEx for Endometrial Cancer Survivors: Initial Efficacy

Carilion Clinic

NCT05737745

COMPLETED NA 106 participants

Non-Hormonal Vaginal Moisturizer in Hormone-Receptor Positive Postmenopausal Cancer Survivors Experiencing Estrogen Deprivation Symptoms on Vulvovaginal Health

Memorial Sloan Kettering Cancer Center

NCT01738152

COMPLETED 100 participants

Lymphedema in Endometrial Cancer

Duke University

NCT01914276

COMPLETED Phase 1 71 participants

Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.

Mundipharma Research Limited

NCT03345485

COMPLETED Phase 4 70 participants

A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment

Eli Lilly and Company

NCT00190697

COMPLETED Phase 2 70 participants

Intravenous Weekly Topotecan In Subjects With Recurrent Or Persistent Endometrial Cancer

GlaxoSmithKline

NCT00267488

COMPLETED Phase 1 65 participants

Pelvic IMRT With Tomotherapy in Post-Hysterectomy Endometrial Cancer Patients

Washington University School of Medicine

NCT00334321

COMPLETED Phase 2 64 participants

SYD985 in Patients With HER2-expressing Recurrent, Advanced or Metastatic Endometrial Carcinoma

Byondis B.V.

NCT04205630

COMPLETED Phase 2 53 participants

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Memorial Sloan Kettering Cancer Center

NCT00474994

COMPLETED Phase 2 52 participants

Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer

National Cancer Institute (NCI)

NCT00033358

COMPLETED Phase 2 49 participants

Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium

University of Oklahoma

NCT03476798

COMPLETED Phase 1 48 participants

A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Arcus Biosciences

NCT03629756

COMPLETED Phase 2 43 participants

A Study of Patients Receiving High-Dose Rate Brachytherapy

National Cancer Institute (NCI)

NCT00924027

COMPLETED Phase 2 38 participants

Evaluation of Carboplatin/Paclitaxel/Bevacizumab in the Treatment of Advanced Stage Endometrial Carcinoma

David O'Malley

NCT00513786

COMPLETED Phase 1 32 participants

Effects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid Tumors

Santa Maria Biotherapeutics

NCT02262455

COMPLETED Phase 1 30 participants

Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women

UNC Lineberger Comprehensive Cancer Center

NCT00099008

COMPLETED NA 25 participants

the Effectiveness of a Weight Management Program in Patients Who Have Completed Treatment for Endometrial Cancer

Sanford Health

NCT03908996

COMPLETED Early Phase 1 24 participants

A Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the Endometrium

UNC Lineberger Comprehensive Cancer Center

NCT02767362

COMPLETED Phase 1 24 participants

Docetaxel and PTK787 in Metastatic Breast Cancer Patients and Gynecological Cancer Patients

Dana-Farber Cancer Institute

NCT00268918

COMPLETED Phase 2 23 participants

A Phase 2 Feasibility Study of Abraxane and Carboplatin in Epithelial Neoplasms of the Uterus

NYU Langone Health

NCT02744898

COMPLETED Phase 2 22 participants

Trial of Maintenance With Niraparib- Uterine Serous Carcinoma

Northwell Health

NCT04080284

COMPLETED Phase 2 21 participants

Gemcitabine and Cisplatin for Advanced or Recurrent Endometrial Cancer

M.D. Anderson Cancer Center

NCT00388154

COMPLETED Phase 2 21 participants

Safety Study Of Avastin And Pelvic Radiation In Women With Recurrent Gynecological Cancers

Dana-Farber Cancer Institute

NCT00545792

COMPLETED Early Phase 1 21 participants

Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer

M.D. Anderson Cancer Center

NCT01205672

COMPLETED Phase 2 18 participants

CerviPrep for Applying Topical Gemcitabine to the Cervix in Treating Patients With Primary Endometrial, Cervical, or Ovarian Epithelial Cancer

Masonic Cancer Center, University of Minnesota

NCT00610740

COMPLETED Phase 1 15 participants

Topotecan in Combination With Pemetrexed in Patients With Advanced Malignancies

SCRI Development Innovations

NCT00315861

COMPLETED NA 15 participants

Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer

University of Wisconsin, Madison

NCT02096783

COMPLETED Phase 2

Irofulven in Treating Patients With Persistent or Recurrent, Refractory Endometrial Cancer

Gynecologic Oncology Group

NCT00005031

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract

NYU Langone Health

NCT00003334

COMPLETED Phase 3

Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer

Radiation Therapy Oncology Group

NCT00006027

COMPLETED Phase 1

Combination Chemotherapy in Treating Patients With Previously Untreated, Newly Diagnosed Epithelial Tumors

Beth Israel Deaconess Medical Center

NCT00004082

COMPLETED Phase 2

Doxorubicin, Paclitaxel, and Carboplatin in Treating Patients With Primary Stage III, Stage IV, or Recurrent Endometrial Cancer

Memorial Sloan Kettering Cancer Center

NCT00006377

COMPLETED Phase 3

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer

Gynecologic Oncology Group

NCT00002493

← Previous Page 4 of 4

Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 44
Phase 3 14
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Endometrial Cancer Trial Landscape

188 indexed Endometrial Cancer studies · 108 recruiting (57%).

Phase mix: 15 late (III/IV) vs 118 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (17 trials), 9 others listed. 38 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Endometrial Cancer?

PlainTrial tracks 188 US clinical trials for Endometrial Cancer, of which 108 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Endometrial Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.