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Endometrial Cancer clinical trials
108 of 188 indexed Endometrial Cancer trials are currently recruiting.
188 US clinical trials · 108 currently recruiting
Endometrial Cancer is the subject of 188 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 118 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 17 of these trials.
The research picture
Endometrial Cancer has 188 registered US clinical trials, 108 of them open to new participants right now, about 57% of the total.
- 108
- recruiting participants now
- 57%
- of trials open to enrollment
- 15
- in Phase 3–4 (later-stage)
- 17
- top sponsor: Memorial Sloan Kettering Cancer Center
Active & Recent Trials
188 total, page 4 of 4
Lymph Node Mapping in Patients With Endometrial Cancer
Ohio State University Comprehensive Cancer Center
NCT01818739
A Study Assessing the Safety and Utility of PINPOINT® Near Infrared Fluorescence Imaging in the Identification of Lymph Nodes in Patients With Uterine and Cervical Malignancies Who Are Undergoing Lymph Node Mapping
Novadaq Technologies ULC, now a part of Stryker
NCT02209532
Scale Down for Endometrial Cancer
Washington University School of Medicine
NCT03169023
Intra-Operative Lymphatic Mapping in Patients With Invasive Carcinoma of the Cervix or Endometrial Carcinoma
Memorial Sloan Kettering Cancer Center
NCT00595725
A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors
Incyte Corporation
NCT03314935
FitEx for Endometrial Cancer Survivors: Initial Efficacy
Carilion Clinic
NCT05737745
Non-Hormonal Vaginal Moisturizer in Hormone-Receptor Positive Postmenopausal Cancer Survivors Experiencing Estrogen Deprivation Symptoms on Vulvovaginal Health
Memorial Sloan Kettering Cancer Center
NCT01738152
Lymphedema in Endometrial Cancer
Duke University
NCT01914276
Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.
Mundipharma Research Limited
NCT03345485
A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment
Eli Lilly and Company
NCT00190697
Intravenous Weekly Topotecan In Subjects With Recurrent Or Persistent Endometrial Cancer
GlaxoSmithKline
NCT00267488
Pelvic IMRT With Tomotherapy in Post-Hysterectomy Endometrial Cancer Patients
Washington University School of Medicine
NCT00334321
SYD985 in Patients With HER2-expressing Recurrent, Advanced or Metastatic Endometrial Carcinoma
Byondis B.V.
NCT04205630
Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas
Memorial Sloan Kettering Cancer Center
NCT00474994
Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer
National Cancer Institute (NCI)
NCT00033358
Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium
University of Oklahoma
NCT03476798
A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies
Arcus Biosciences
NCT03629756
A Study of Patients Receiving High-Dose Rate Brachytherapy
National Cancer Institute (NCI)
NCT00924027
Evaluation of Carboplatin/Paclitaxel/Bevacizumab in the Treatment of Advanced Stage Endometrial Carcinoma
David O'Malley
NCT00513786
Effects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid Tumors
Santa Maria Biotherapeutics
NCT02262455
Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women
UNC Lineberger Comprehensive Cancer Center
NCT00099008
the Effectiveness of a Weight Management Program in Patients Who Have Completed Treatment for Endometrial Cancer
Sanford Health
NCT03908996
A Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the Endometrium
UNC Lineberger Comprehensive Cancer Center
NCT02767362
Docetaxel and PTK787 in Metastatic Breast Cancer Patients and Gynecological Cancer Patients
Dana-Farber Cancer Institute
NCT00268918
A Phase 2 Feasibility Study of Abraxane and Carboplatin in Epithelial Neoplasms of the Uterus
NYU Langone Health
NCT02744898
Trial of Maintenance With Niraparib- Uterine Serous Carcinoma
Northwell Health
NCT04080284
Gemcitabine and Cisplatin for Advanced or Recurrent Endometrial Cancer
M.D. Anderson Cancer Center
NCT00388154
Safety Study Of Avastin And Pelvic Radiation In Women With Recurrent Gynecological Cancers
Dana-Farber Cancer Institute
NCT00545792
Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer
M.D. Anderson Cancer Center
NCT01205672
CerviPrep for Applying Topical Gemcitabine to the Cervix in Treating Patients With Primary Endometrial, Cervical, or Ovarian Epithelial Cancer
Masonic Cancer Center, University of Minnesota
NCT00610740
Topotecan in Combination With Pemetrexed in Patients With Advanced Malignancies
SCRI Development Innovations
NCT00315861
Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer
University of Wisconsin, Madison
NCT02096783
Irofulven in Treating Patients With Persistent or Recurrent, Refractory Endometrial Cancer
Gynecologic Oncology Group
NCT00005031
Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract
NYU Langone Health
NCT00003334
Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer
Radiation Therapy Oncology Group
NCT00006027
Combination Chemotherapy in Treating Patients With Previously Untreated, Newly Diagnosed Epithelial Tumors
Beth Israel Deaconess Medical Center
NCT00004082
Doxorubicin, Paclitaxel, and Carboplatin in Treating Patients With Primary Stage III, Stage IV, or Recurrent Endometrial Cancer
Memorial Sloan Kettering Cancer Center
NCT00006377
Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer
Gynecologic Oncology Group
NCT00002493
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 74 |
| Phase 2 | 44 |
| Phase 3 | 14 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Endometrial Cancer Trial Landscape
188 indexed Endometrial Cancer studies · 108 recruiting (57%).
Phase mix: 15 late (III/IV) vs 118 early (I/II).
Top sponsor: Memorial Sloan Kettering Cancer Center (17 trials), 9 others listed. 38 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Endometrial Cancer?
PlainTrial tracks 188 US clinical trials for Endometrial Cancer, of which 108 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Endometrial Cancer?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.