Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer

NCT00002493 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which treatment regimen is more effective for endometrial cancer. PURPOSE: Randomized phase III trial to compare radiation therapy with chemotherapy in treating patients who have advanced endometrial cancer.

Interventions

  • DRUG cisplatin
  • DRUG doxorubicin hydrochloride
  • RADIATION low-LET photon therapy

Study Locations (20)

California

  • USC/Norris Comprehensive Cancer Center — Los Angeles
  • Jonsson Comprehensive Cancer Center, UCLA — Los Angeles
  • Chao Family Comprehensive Cancer Center — Orange
  • Women's Cancer Center — Palo Alto
  • Stanford University Medical Center — Stanford

District of Columbia

  • Vincent T. Lombardi Cancer Research Center, Georgetown University — Washington D.C.
  • Walter Reed Army Medical Center — Washington D.C.

Georgia

  • Emory University Hospital - Atlanta — Atlanta
  • CCOP - Atlanta Regional — Atlanta

Illinois

  • Rush-Presbyterian-St. Luke's Medical Center — Chicago
  • University of Chicago Cancer Research Center — Chicago

Alabama

  • University of Alabama Comprehensive Cancer Center — Birmingham

Arizona

  • CCOP - Greater Phoenix — Phoenix

Colorado

  • University of Colorado Cancer Center — Denver

Florida

  • H. Lee Moffitt Cancer Center and Research Institute — Tampa

Trial Details

FieldValue
Start Date 1992-05
Phase Phase 3

Sponsor

Gynecologic Oncology Group

61 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00002493

The ClinicalTrials.gov registry entry for NCT00002493 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Gynecologic Oncology Group, which has 61 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Endometrial Cancer appearing as the primary indexed condition, and to 3 interventions — of which cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00002493 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, District of Columbia, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00002493 about?

NCT00002493 is a clinical study titled "Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which treatment regimen is more effective for endometrial cancer. PURPOSE: Randomized phase II...

What is the current status of trial NCT00002493?

This trial is currently completed. It is a Phase 3 study. The study started on 1992-05.

What conditions does trial NCT00002493 study?

This clinical trial studies the following conditions: Endometrial Cancer, Psychosocial Effects of Cancer and Its Treatment. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00002493?

The interventions under investigation include: cisplatin (DRUG), doxorubicin hydrochloride (DRUG), low-LET photon therapy (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00002493?

This trial is sponsored by Gynecologic Oncology Group, which has 61 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00002493 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial