Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00006027 · ClinicalTrials.gov registry record · Phase 3
Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer
A Phase 3 study of Endometrial Cancer, sponsored by Radiation Therapy Oncology Group.
- Completed
- Registry status
- Phase 3
- Development phase
- 20
- Study locations
NCT00006027: Completed Phase 3 study of Endometrial Cancer, sponsored by Radiation Therapy Oncology Group.
NCT00006027 is a Phase 3 study of Endometrial Cancer that has completed, run by Radiation Therapy Oncology Group. The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00006027, a Phase 3 study of Endometrial Cancer, has completed, sponsored by Radiation Therapy Oncology Group.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 20
- Study locations
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor tissue. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if radiation therapy is more effective with or without combination chemotherapy for endometrial cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without combination chemotherapy following surgery in treating patients who have stage I or stage II endometrial cancer.
Conditions Studied
Interventions
- DRUG cisplatin
- DRUG paclitaxel
- RADIATION radiation therapy
- PROCEDURE adjuvant therapy
Study Locations (20)
California
- Jonsson Comprehensive Cancer Center, UCLA - Los Angeles
- Community Hospital of Los Gatos - Los Gatos
- Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center - Orange
New York
- State University of New York Health Science Center at Brooklyn - Brooklyn
- Memorial Sloan-Kettering Cancer Center - New York
- Long Island Cancer Center at Stony Brook University Hospital - Stony Brook
North Carolina
- Lineberger Comprehensive Cancer Center, UNC - Chapel Hill
- Duke Comprehensive Cancer Center - Durham
- Comprehensive Cancer Center at Wake Forest University - Winston-Salem
Colorado
- University of Colorado Cancer Center at University of Colorado Health Sciences Center - Denver
Hawaii
- MBCCOP - Hawaii - Honolulu
Indiana
- Indiana University Cancer Center - Indianapolis
Iowa
- Holden Comprehensive Cancer Center at University of Iowa - Iowa City
Maryland
- Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support - Bethesda
Trial Details
| Field | Value |
|---|---|
| Start Date | 2000-08 |
| Phase | Phase 3 |
What the finished NCT00006027 record still lists
NCT00006027 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 1 condition, with Endometrial Cancer appearing as the primary indexed condition, and to 4 interventions - of which cisplatin is the first listed.
NCT00006027 names 20 study sites across 14 states, led by California, New York, North Carolina.
Frequently Asked Questions
What is clinical trial NCT00006027 about?
NCT00006027 is a clinical study titled "Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor tissue. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if radiation therapy is more effective with or without combination chemotherapy for endometria...
What is the current status of trial NCT00006027?
This trial is currently completed. It is a Phase 3 study. The study started on 2000-08.
What conditions does trial NCT00006027 study?
This clinical trial studies the following conditions: Endometrial Cancer.
What interventions are being tested in trial NCT00006027?
The interventions under investigation include: cisplatin (DRUG), paclitaxel (DRUG), radiation therapy (RADIATION), adjuvant therapy (PROCEDURE).
Who is sponsoring clinical trial NCT00006027?
This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00006027 being conducted?
This trial has 20 study locations across California, Colorado, Hawaii, Indiana, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Endometrial Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
RECRUITING · Phase 3
-
Vaginal Cuff Brachytherapy Fractionation Study
RECRUITING · Phase 3
-
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
RECRUITING · Phase 3
-
Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
RECRUITING · Phase 3
-
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
RECRUITING · Phase 3
-
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
RECRUITING · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia