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NCT00006027 · ClinicalTrials.gov registry record · Phase 3

Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer

A Phase 3 study of Endometrial Cancer, sponsored by Radiation Therapy Oncology Group.

Completed
Registry status
Phase 3
Development phase
20
Study locations

NCT00006027 is a Phase 3 study of Endometrial Cancer that has completed, run by Radiation Therapy Oncology Group. The trial reports 20 study locations across 14 states.

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The verdict

NCT00006027, a Phase 3 study of Endometrial Cancer, has completed, sponsored by Radiation Therapy Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
20
Study locations

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor tissue. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if radiation therapy is more effective with or without combination chemotherapy for endometrial cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without combination chemotherapy following surgery in treating patients who have stage I or stage II endometrial cancer.

Conditions Studied

Endometrial Cancer

Interventions

  • DRUG cisplatin
  • DRUG paclitaxel
  • RADIATION radiation therapy
  • PROCEDURE adjuvant therapy

Study Locations (20)

California

  • Jonsson Comprehensive Cancer Center, UCLA - Los Angeles
  • Community Hospital of Los Gatos - Los Gatos
  • Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center - Orange

New York

  • State University of New York Health Science Center at Brooklyn - Brooklyn
  • Memorial Sloan-Kettering Cancer Center - New York
  • Long Island Cancer Center at Stony Brook University Hospital - Stony Brook

North Carolina

  • Lineberger Comprehensive Cancer Center, UNC - Chapel Hill
  • Duke Comprehensive Cancer Center - Durham
  • Comprehensive Cancer Center at Wake Forest University - Winston-Salem

Colorado

  • University of Colorado Cancer Center at University of Colorado Health Sciences Center - Denver

Hawaii

  • MBCCOP - Hawaii - Honolulu

Indiana

  • Indiana University Cancer Center - Indianapolis

Iowa

  • Holden Comprehensive Cancer Center at University of Iowa - Iowa City

Maryland

  • Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support - Bethesda

Trial Details

FieldValue
Start Date 2000-08
Phase Phase 3

Sponsor

Radiation Therapy Oncology Group

144 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00006027

The ClinicalTrials.gov registry entry for NCT00006027 describes a study currently listed as completed, categorized as Phase 3. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Radiation Therapy Oncology Group, which has 144 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Endometrial Cancer appearing as the primary indexed condition, and to 4 interventions - of which cisplatin is the first listed.

NCT00006027 reports 20 study locations spanning 14 distinct geographic areas - top geographies include California, New York, North Carolina.

Frequently Asked Questions

What is clinical trial NCT00006027 about?

NCT00006027 is a clinical study titled "Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor tissue. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if radiation therapy is more effective with or without combination chemotherapy for endometria...

What is the current status of trial NCT00006027?

This trial is currently completed. It is a Phase 3 study. The study started on 2000-08.

What conditions does trial NCT00006027 study?

This clinical trial studies the following conditions: Endometrial Cancer.

What interventions are being tested in trial NCT00006027?

The interventions under investigation include: cisplatin (DRUG), paclitaxel (DRUG), radiation therapy (RADIATION), adjuvant therapy (PROCEDURE).

Who is sponsoring clinical trial NCT00006027?

This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00006027 being conducted?

This trial has 20 study locations across California, Colorado, Hawaii, Indiana, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.