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NCT00924027 · ClinicalTrials.gov registry record · Phase 2

A Study of Patients Receiving High-Dose Rate Brachytherapy

A Phase 2 study of Prostate Cancer and Endometrial Cancer, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
43
Enrollment target
1
Study location

NCT00924027 is a Phase 2 study of Prostate Cancer and Endometrial Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 43 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00924027, a Phase 2 study of Prostate Cancer and Endometrial Cancer, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
43 participants
Enrollment target
1
Study location

Study Summary

Background: * One standard way of giving radiation is to combine external beam treatments with internal brachytherapy treatments, which involve short-range radiation therapy that gives a high dose of radiation directly to a cancer or to the area where cancer cells were removed. * Brachytherapy is done by placing hollow implant device(s) into the area to be treated and then moving a radiation source into each. The type of device depends on the type of cancer and the site to be treated. These devices can range from hollow applicators and needles to balloon-like equipment. Objectives: * To evaluate the quality of the brachytherapy procedure at the National Institutes of Health Radiation Oncology Branch. Eligibility: * Patients with cancer who could potentially benefit from high-dose brachytherapy as part of their treatment. Design: * In conjunction with their existing treatment, patients will be treated with high-dose brachytherapy as determined appropriate for their particular type of cancer and cancer history. * Each treatment will take place in the Radiation Oncology Clinic. * If the patient does not have implant devices, the clinic staff will insert them and check their placement through a computed tomography (CT) scan. * The calculations to determine the appropriate brachytherapy dose will take a few hours; the brachytherapy treatment itself will take between 10 and 30 minutes. * The number of brachytherapy treatments will vary according to the individual needs and requirements of each type of cancer and each patient. * Patients will return to the Radiation Oncology Clinic for follow-up visits at 1, 3, 6, 9, and 12 months after the completion of radiation therapy. Follow-up evaluations will include a medical history and physical examination, assessment of any side effects of radiation therapy, and a repeat of any imaging (i.e., CT, magnetic resonance imaging (MRI), X-ray) that was done at baseline to evaluate the tumor response.

Interventions

  • DIAGNOSTIC_TEST MRI
  • DIAGNOSTIC_TEST CT
  • DIAGNOSTIC_TEST PET Scan
  • RADIATION High Dose Radiation (HDR) Brachytherapy

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2009-04-14
Est. Completion 2025-07-24
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00924027

The ClinicalTrials.gov registry entry for NCT00924027 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (93% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 4 interventions - of which MRI is the first listed.

NCT00924027 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00924027 about?

NCT00924027 is a clinical study titled "A Study of Patients Receiving High-Dose Rate Brachytherapy". Background: * One standard way of giving radiation is to combine external beam treatments with internal brachytherapy treatments, which involve short-range radiation therapy that gives a high dose of radiation directly to a cancer or to the area where cancer cells were removed. * Brachytherapy is d...

What is the current status of trial NCT00924027?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2009-04-14. Estimated completion is 2025-07-24.

What conditions does trial NCT00924027 study?

This clinical trial studies the following conditions: Prostate Cancer, Endometrial Cancer, Cervical Cancer, Esophageal Cancer, Biliary Cancer.

What interventions are being tested in trial NCT00924027?

The interventions under investigation include: MRI (DIAGNOSTIC_TEST), CT (DIAGNOSTIC_TEST), PET Scan (DIAGNOSTIC_TEST), High Dose Radiation (HDR) Brachytherapy (RADIATION).

Who is sponsoring clinical trial NCT00924027?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00924027 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.