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Emphysema: full-pipeline trial registry
8 of 27 indexed Emphysema trials are currently recruiting.
Corpus placement: #598 of 28,707 conditions by registered trial count.
27 US clinical trials · 8 currently recruiting · #598 of 28,707 conditions by registered trial count
Emphysema: 27 US clinical trials tracked, 8 recruiting.
Emphysema is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Olympus Corporation of the Americas, running 2 of these trials.
Enrollment posture brief
Registry condition emphysema
OPEN 8 | RECR 30% | LATE 5 | EARLY 7 | RANK #598 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Substance-Related Disorders (30% recruiting · 64 trials)
Emphysema lists 8 open slots (30% of 27 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Emphysema on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Emphysema is recruiting below its size-band peers.
8 of 27 indexed trials (29.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Emphysema trials is spread across many organizations.
Olympus Corporation of the Americas accounts for 2 of 27 trials (7.4%). 24 distinct sponsors appear on at least one study for this condition label.
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Typical Emphysema enrolment sits around 150 participants.
Median target enrolment is 150 among the 26 trials that report a genuine target (sentinel values excluded). 10 of those (38.5%) plan for fewer than 100 participants.
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Emphysema splits between interventional and observational designs.
18 interventional and 9 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
27 total, page 1 of 1
COPD Patient-Powered Research Network
COPD Foundation
NCT02803242
Emphysema Research Registry and Biosample Repository
University of Pittsburgh
NCT00307281
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Apreo Health
NCT06891755
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema
Sanofi
NCT05897424
STRIVE Post-Market Registry Study
Olympus Corporation of the Americas
NCT04302272
Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
The Cleveland Clinic
NCT07059637
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
Gelb, Arthur F., M.D.
NCT03263130
Biological Effects of Quercetin in COPD Phase II
Temple University
NCT06003270
Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)
Brigham and Women's Hospital
NCT00608764
Study of COPD Subgroups and Biomarkers
University of North Carolina, Chapel Hill
NCT01969344
Zephyr Valve Registry (ZEVR)
Pulmonx Corporation
NCT04186546
Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial)
Weill Medical College of Cornell University
NCT05382208
Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema
Eric A. Hoffman
NCT02682147
Determine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPD
Sumitomo Pharma America
NCT00064402
Safety and Efficacy of Arformoterol Tartrate Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease
Sumitomo Pharma America
NCT00250679
Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema
Olympus Corporation of the Americas
NCT00475007
Evaluating Genetic Factors That May Contribute to Elastin Function and the Development of Chronic Obstructive Pulmonary Disease
Washington University School of Medicine
NCT00725309
Losartan Effects on Emphysema Progression
JHSPH Center for Clinical Trials
NCT02696564
Prostaglandin Inhibition for Emphysema
University of Nebraska
NCT02006576
Alpha-1 Carrier Genomics Study
Medical University of South Carolina
NCT02810327
Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation
Johns Hopkins University
NCT00181207
Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen
Hal C Charles
NCT01710449
Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
University of North Carolina, Chapel Hill
NCT01615484
Real-Time Support for Exercise Persistence in COPD
University of Washington
NCT00373932
Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies
University of Alabama at Birmingham
NCT03244059
A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients
Mayo Clinic
NCT03814980
Lung Volume Reductions Surgery (LVRS) Study
US Department of Veterans Affairs
NCT00018525
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 5 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Emphysema records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Emphysema trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Emphysema page
27 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Emphysema trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Olympus Corporation of the Americas sponsors the most Emphysema trials on record, review their full trial history before evaluating a specific study. See Olympus Corporation of the Americas's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Emphysema condition card totals 27 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.