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NCT02810327 · ClinicalTrials.gov registry record
Alpha-1 Carrier Genomics Study
A clinical trial of Smoking and COPD, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- 117
- Enrollment target
- 1
- Study location
NCT02810327: Completed study of Smoking and COPD, sponsored by Medical University of South Carolina.
NCT02810327 is a study of Smoking and COPD that has completed, run by Medical University of South Carolina. The registered enrollment target is 117 participants, below the 454-participant average among 123 other Smoking trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02810327, a study of Smoking and COPD, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- 117 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to better understand why some Alpha-1 genotype MZ (PiMZ) individuals develop chronic obstructive pulmonary disease (COPD) while others do not. This study will examine portions of the Alpha-1 gene that are not routinely tested to determine whether other changes in this gene correlate with development and progression of COPD. Participation involves responding to questionnaires about lung health and history, and performing an at-home finger stick to obtain blood spots using a test kit that is mailed. The blood provided will be used for genetic testing and correlation of results with COPD history. Participants will receive their results and access to genetic counseling at the conclusion of the study.
Primary Outcome
Additional SERPINA1 variant of known or possible significance detected by next generation sequencing.
Conditions Studied
Interventions
- GENETIC Genetic Sequencing
Study Locations (1)
South Carolina
- Medical University of South Carolina. Division of Pulmonary and Critical Care Medicine - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 117 participants |
| Start Date | 2015-02 |
| Est. Completion | 2017-04 |
What the finished NCT02810327 record still lists
NCT02810327 is an observational study that tracks outcomes without assigning an intervention. The registered 117 participants enrollment target is mid-sized for trials with a published cap, below the 454-participant average among 123 other Smoking trials with a reported enrollment target (74% lower).
The record links to 4 conditions, with Smoking appearing as the primary indexed condition, and to 1 intervention - of which Genetic Sequencing is the first listed.
NCT02810327 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT02810327 about?
NCT02810327 is a clinical study titled "Alpha-1 Carrier Genomics Study". The goal of this study is to better understand why some Alpha-1 genotype MZ (PiMZ) individuals develop chronic obstructive pulmonary disease (COPD) while others do not. This study will examine portions of the Alpha-1 gene that are not routinely tested to determine whether other changes in this gene ...
What is the current status of trial NCT02810327?
This trial is currently completed. The enrollment target is 117 participants. The study started on 2015-02. Estimated completion is 2017-04.
What conditions does trial NCT02810327 study?
This clinical trial studies the following conditions: Smoking, COPD, Emphysema, Alpha-1 Antitrypsin Deficiency.
What interventions are being tested in trial NCT02810327?
The interventions under investigation include: Genetic Sequencing (GENETIC).
Who is sponsoring clinical trial NCT02810327?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02810327 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02810327's enrollment target sits among peer trials
117 66th of 123 higher than 57 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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