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ACTIVE NOT RECRUITING

Zephyr Valve Registry (ZEVR)

NCT04186546 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this Post-Approval Registry is to gather ongoing safety and effectiveness assessment of the Zephyr Valve treatment in a real-world setting.

Conditions Studied

Interventions

  • DEVICE Zephyr Valve Procedure

Study Locations (11)

Pennsylvania

  • The Lung Center — DuBois
  • University of Pennsylvania — Philadelphia
  • Temple University Hospital — Philadelphia
  • University of Pittsburgh School of Medicine — Pittsburgh

Illinois

  • University of Chicago — Chicago
  • Northwestern Medicine — Winfield

Alabama

  • University of Alabama at Birmingham — Birmingham

Michigan

  • Henry Ford Hospital — Detroit

Texas

  • Houston Methodist — Houston

Virginia

  • Inova Health — Fairfax

Wisconsin

  • Froedtert Memorial-Medical College of Wisconsin — Milwaukee

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2019-11-25
Est. Completion 2026-12-31

Sponsor

Pulmonx Corporation

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04186546

The ClinicalTrials.gov registry entry for NCT04186546 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pulmonx Corporation, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Emphysema appearing as the primary indexed condition, and to 1 intervention — of which Zephyr Valve Procedure is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04186546 reports 11 study locations spanning 7 distinct geographic areas — top geographies include Pennsylvania, Illinois, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04186546 about?

NCT04186546 is a clinical study titled "Zephyr Valve Registry (ZEVR)". The purpose of this Post-Approval Registry is to gather ongoing safety and effectiveness assessment of the Zephyr Valve treatment in a real-world setting.

What is the current status of trial NCT04186546?

This trial is currently active not recruiting. The enrollment target is 150 participants. The study started on 2019-11-25. Estimated completion is 2026-12-31.

What conditions does trial NCT04186546 study?

This clinical trial studies the following conditions: Emphysema. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04186546?

The interventions under investigation include: Zephyr Valve Procedure (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04186546?

This trial is sponsored by Pulmonx Corporation, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04186546 being conducted?

This trial has 11 study locations across Alabama, Illinois, Michigan, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial