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Diabetes clinical trials
86 of 342 indexed Diabetes trials are currently recruiting.
342 US clinical trials · 86 currently recruiting
Diabetes is the subject of 342 registered US clinical trials on ClinicalTrials.gov, 86 of them currently open to new participants. 55 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 41 of these trials.
The research picture
Diabetes has 342 registered US clinical trials, 86 of them open to new participants right now, about 25% of the total.
- 86
- recruiting participants now
- 25%
- of trials open to enrollment
- 55
- in Phase 3–4 (later-stage)
- 41
- top sponsor: Novo Nordisk A/S
Active & Recent Trials
342 total, page 3 of 7
Insulin Balanced Infusion System
Admetsys Corporation
NCT01291719
REsearching Covid-19 Outcomes in Diabetes (RECODE)
AdventHealth Translational Research Institute
NCT04805970
Monitoring Your Exercise-related Metrics Over Time Via Wearable Electronic Devices
M.D. Anderson Cancer Center
NCT05124405
Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02262806
Patient Specific 3D Printed Diabetic Insoles to Reduce Plantar Pressure
VA Office of Research and Development
NCT05301478
CharacterIzation of Adult Onset Autoimmune Diabetes
AdventHealth Translational Research Institute
NCT03971955
I Can Do This! Managing My Diabetes
Emory University
NCT06695533
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02262832
Replication of the LEADER Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital
NCT03936049
Replication of the EMPAREG Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital
NCT04215536
Replication of the CARMELINA Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital
NCT03936036
Effect of Reminders on Adherence
University of Pennsylvania
NCT02411006
Improving Service Delivery Through Access Points
US Department of Veterans Affairs
NCT00012623
Estimation of Malignancy Rates Within Humedica Patient Populations Sampled to be Representative of Liraglutide Initiators and LEADER™ Trial Participants
Novo Nordisk A/S
NCT02608853
Environmental Polymorphisms Registry Health and Exposures Survey
National Institute of Environmental Health Sciences (NIEHS)
NCT01688986
A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events
Novo Nordisk A/S
NCT01959529
Cooking for Health Optimization With Patients
Tulane University
NCT03443635
INITIATE Plus (INITiation of Insulin to Reach A1c TargEt) Study
Novo Nordisk A/S
NCT00101751
Adherence and Intensification of Medications (AIM) Implementation Study
US Department of Veterans Affairs
NCT00495794
Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era
VA Office of Research and Development
NCT00958061
Diabetes in the Perioperative Period
Emory University
NCT00738114
Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes
Novo Nordisk A/S
NCT01336023
A Trial Comparing the Efficacy and Safety of Insulin Degludec and Insulin Glargine 300 Units/mL in Subjects With Type 2 Diabetes Mellitus Inadequately Treated With Basal Insulin With or Without Oral Antidiabetic Drugs
Novo Nordisk A/S
NCT03078478
Addressing Diffusion of Responsibility and Prescribing Burden to Improve Use of Diabetes Medications
Brigham and Women's Hospital
NCT05463705
The Efficacy and Safety of Liraglutide as Adjunct Therapy to Insulin in the Treatment of Type 1 Diabetes
Novo Nordisk A/S
NCT01836523
Family Management of Childhood Diabetes Study
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00340938
"Working for You" Workplace Obesity Intervention
Washington University School of Medicine
NCT02934113
Insulin Treatment Variation in Southwestern Diabetics
VA Office of Research and Development
NCT00148304
Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes.
Novo Nordisk A/S
NCT02648204
Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial
University of Virginia
NCT01369069
Study of a Holistic Health Program for United Methodist Clergy
Duke Clergy Health Initiative
NCT01564719
Efficacy and Safety of Faster-acting Insulin Aspart Compared to NovoRapid® Both in Combination With Insulin Degludec in Adults With Type 1 Diabetes
Novo Nordisk A/S
NCT02500706
Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes
Novo Nordisk A/S
NCT02128932
Comparison of NN1250 With Insulin Glargine Plus Insulin Aspart With/Without Metformin and With/Without Pioglitazone in Type 2 Diabetes
Novo Nordisk A/S
NCT00972283
Improving Self Management Skills of Older Adults With Diabetes
Stanford University
NCT01943357
A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time
Eli Lilly and Company
NCT05362058
Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination With Insulin Glargine and Metformin in Adults With Type 2 Diabetes
Novo Nordisk A/S
NCT01819129
Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects With Type 2 Diabetes Mellitus
Novo Nordisk A/S
NCT02863328
Efficacy and Safety of Semaglutide Once-weekly Versus Exenatide ER 2.0 mg Once-weekly as add-on to 1-2 Oral Antidiabetic Drugs (OADs) in Subjects With Type 2 Diabetes
Novo Nordisk A/S
NCT01885208
CARDIA Brain MRI Substudy
National Institute on Aging (NIA)
NCT01273311
Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus
Novo Nordisk A/S
NCT02863419
A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy
Eli Lilly and Company
NCT05463744
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
Novo Nordisk A/S
NCT00700817
The CREATE Wellness Study
Kaiser Permanente
NCT02302612
Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes
Novo Nordisk A/S
NCT01923181
Comparison of NN1250 Plus Insulin Aspart With Insulin Glargine Plus Insulin Aspart in Type 1 Diabetes
Novo Nordisk A/S
NCT00982228
Impact of Dietary Intervention on Weight Change in Subjects With Type 2 Diabetes
Novo Nordisk A/S
NCT01232491
Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)
University of Utah
NCT02470156
Comparison of NN5401 Plus Insulin Aspart With Insulin Detemir Plus Insulin Aspart in Type 1 Diabetes
Novo Nordisk A/S
NCT00978627
NovoLog Observation Trial in Subjects With Type 1 and Type 2 Diabetes
Novo Nordisk A/S
NCT00095446
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 23 |
| Phase 2 | 13 |
| Phase 3 | 37 |
| Phase 4 | 18 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Diabetes Trial Landscape
342 indexed Diabetes studies · 86 recruiting (25%).
Phase mix: 55 late (III/IV) vs 36 early (I/II).
Top sponsor: Novo Nordisk A/S (41 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Diabetes?
PlainTrial tracks 342 US clinical trials for Diabetes, of which 86 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Diabetes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.