Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes
NCT02128932 · View on ClinicalTrials.gov ↗
Study Summary
This trial is conducted in Africa, North and South America, Asia and Europe. The purpose of the trial is to compare the effect of once-weekly dosing of two dose levels of semaglutide versus insulin glargine once-daily on glycaemic control after 30 weeks of treatment in insulin-naïve subjects with type 2 diabetes.
Conditions Studied
Interventions
- DRUG semaglutide
- DRUG insulin glargine
Study Locations (20)
California
- Novo Nordisk Investigational Site — Anaheim
- Novo Nordisk Investigational Site — Carmichael
- Novo Nordisk Investigational Site — Chula Vista
- Novo Nordisk Investigational Site — Elk Grove
- Novo Nordisk Investigational Site — Inglewood
- Novo Nordisk Investigational Site — La Mesa
- Novo Nordisk Investigational Site — Long Beach
- Novo Nordisk Investigational Site — Los Angeles
- Novo Nordisk Investigational Site — Oceanside
- Novo Nordisk Investigational Site — Orange
- Novo Nordisk Investigational Site — Pomona
- Novo Nordisk Investigational Site — Rialto
- Novo Nordisk Investigational Site — Rolling Hills Estates
- Novo Nordisk Investigational Site — Roseville
Alabama
- Novo Nordisk Investigational Site — Birmingham
- Novo Nordisk Investigational Site — Ozark
- Novo Nordisk Investigational Site — Tuscumbia
Arizona
- Novo Nordisk Investigational Site — Gilbert
- Novo Nordisk Investigational Site — Phoenix
- Novo Nordisk Investigational Site — Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,089 participants |
| Start Date | 2014-08-04 |
| Est. Completion | 2015-09-03 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02128932
The ClinicalTrials.gov registry entry for NCT02128932 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,089 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Diabetes appearing as the primary indexed condition, and to 2 interventions — of which semaglutide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02128932 reports 20 study locations spanning 3 distinct geographic areas — top geographies include California, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02128932 about?
NCT02128932 is a clinical study titled "Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes". This trial is conducted in Africa, North and South America, Asia and Europe. The purpose of the trial is to compare the effect of once-weekly dosing of two dose levels of semaglutide versus insulin glargine once-daily on glycaemic control after 30 weeks of treatment in insulin-naïve subjects with ty...
What is the current status of trial NCT02128932?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,089 participants. The study started on 2014-08-04. Estimated completion is 2015-09-03.
What conditions does trial NCT02128932 study?
This clinical trial studies the following conditions: Diabetes, Diabetes Mellitus, Type 2. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02128932?
The interventions under investigation include: semaglutide (DRUG), insulin glargine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02128932?
This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02128932 being conducted?
This trial has 20 study locations across Alabama, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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