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ClinicalTrials.gov 86 recruiting now later-stage tilt #19 of 28,707 conditions

Diabetes: later-stage trial registry

86 of 342 indexed Diabetes trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #19 of 28,707 conditions by registered trial count.

342 US clinical trials · 86 currently recruiting · #19 of 28,707 conditions by registered trial count

Diabetes: 342 US clinical trials tracked, 86 recruiting.

Diabetes is the subject of 342 registered US clinical trials on ClinicalTrials.gov, 86 of them currently open to new participants. 55 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 41 of these trials.

Enrollment posture brief

Registry condition diabetes

OPEN 86 | RECR 25% | LATE 55 | EARLY 36 | RANK #19 | SPON 41

Nearest open-share peer: Low Back Pain (25% recruiting · 123 trials)

Ovarian Cancer43.5%Type 2 Diabetes36.6%Lymphoma26.7%Diabetes (this)25%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Diabetes

Diabetes lists 86 open slots (25% of 342 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Diabetes is recruiting below its size-band peers.

    86 of 342 indexed trials (25.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Diabetes trials is spread across many organizations.

    Novo Nordisk A/S accounts for 41 of 342 trials (12%). 161 distinct sponsors appear on at least one study for this condition label.

  3. Typical Diabetes enrolment sits around 150 participants.

    Median target enrolment is 150 among the 339 trials that report a genuine target (sentinel values excluded). 144 of those (42.5%) plan for fewer than 100 participants.

  4. Diabetes research is mostly interventional.

    263 interventional and 79 observational studies make up this index (76.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 123Phase 213Phase 337Phase 418

Open and recent trials

342 total, page 4 of 7

COMPLETED 509 participants

Evaluation of a Noninvasive Diabetes Screening Device in Subjects at Risk for Diabetes

VeraLight

NCT01080157

COMPLETED Phase 3 503 participants

Comparison of Insulin Detemir Morning, Insulin Detemir Evening and NPH Insulin Evening in Patients With Type 2 Diabetes

Novo Nordisk A/S

NCT00104182

COMPLETED Phase 3 467 participants

Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes

Novo Nordisk A/S

NCT01076647

COMPLETED Phase 3 465 participants

Comparison of NN5401 With Insulin Glargine, Both in Combination With Oral Antidiabetic Drugs, in Subjects With Type 2 Diabetes

Novo Nordisk A/S

NCT01045447

COMPLETED NA 460 participants

Healthy Eating and Active Living Taught at Home

Washington University School of Medicine

NCT01567033

COMPLETED Phase 3 458 participants

Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With Insulin

Novo Nordisk A/S

NCT01046110

COMPLETED Phase 3 435 participants

The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy

Novo Nordisk A/S

NCT01618162

COMPLETED NA 425 participants

Healthy.io Method Comparison & User Performance Study

Healthy.io

NCT02785445

COMPLETED 417 participants

DHS MIND Metabolomics

Wake Forest University Health Sciences

NCT03975309

COMPLETED 400 participants

Wound Assessment Using Spectral Imaging US

SpectralMD

NCT05415683

COMPLETED NA 400 participants

The ABC Planning Study: Diabetes and Cardiovascular Risks in Primary Care

The University of Texas Health Science Center at San Antonio

NCT00223340

COMPLETED NA 400 participants

The Health Access and Recovery Peer Program

Emory University

NCT01725815

COMPLETED NA 392 participants

The GoodNEWS Lifestyle Enhancement Program

University of Texas Southwestern Medical Center

NCT00669630

COMPLETED NA 381 participants

Therapeutic Stockings to Prevent Foot Ulcers

University of Texas Southwestern Medical Center

NCT01221194

COMPLETED NA 376 participants

Evaluation of a Ascensia ONYX NEXT Investigational Blood Glucose Monitoring System

Ascensia Diabetes Care

NCT02390167

COMPLETED Phase 3 373 participants

Comparison of Two Insulin Degludec Formulations in Subjects With Type 2 Diabetes Mellitus

Novo Nordisk A/S

NCT01364428

COMPLETED Phase 3 362 participants

A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes Mellitus

Novo Nordisk A/S

NCT01835431

COMPLETED NA 362 participants

Harnessing Health IT for Self-Management Support and Medication Activation in a Medicaid Health Plan

University of California, San Francisco

NCT00683020

COMPLETED NA 360 participants

Feasibility and Impact of "ABCs of Diabetes" Self-Management Education Program at an Urban Public Library

Medstar Health Research Institute

NCT00822471

COMPLETED NA 355 participants

Enhanced Quality in Primary Care for Elders With Diabetes and Dementia

NYU Langone Health

NCT03723707

COMPLETED NA 348 participants

A Helping Hand Among Low-Income Patients

University of Southern California

NCT02147522

COMPLETED Phase 3 346 participants

The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification

Novo Nordisk A/S

NCT01664247

COMPLETED NA 339 participants

Improving Diabetes Efforts Across Language and Literacy (IDEALL)

Agency for Healthcare Research and Quality (AHRQ)

NCT00214474

COMPLETED NA 338 participants

Growing Resilience in Wind River Indian Reservation

University of Wyoming

NCT02672748

COMPLETED Phase 2 319 participants

Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain

Lexicon Pharmaceuticals

NCT04455633

COMPLETED 310 participants

Family Genetics Health Education and Healthy Behaviors

National Human Genome Research Institute (NHGRI)

NCT01498276

COMPLETED NA 302 participants

Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease

University of Pennsylvania

NCT01900470

COMPLETED NA 302 participants

Men Together Making a Difference: Health Promotion for Black Men

University of Pennsylvania

NCT02572414

COMPLETED Phase 3 302 participants

Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus

Novo Nordisk A/S

NCT03086330

COMPLETED 300 participants

Racial/Ethnic Differences in Trust/Mistrust and Its Effect on Diabetes Outcomes

US Department of Veterans Affairs

NCT00383110

COMPLETED Phase 3 293 participants

Comparison of Biphasic Insulin Aspart 70/30 Versus Insulin Glargine in Subjects With Type 2 Diabetes

Novo Nordisk A/S

NCT00097877

COMPLETED NA 292 participants

Multicenter Worksite Nutrition Study

Physicians Committee for Responsible Medicine

NCT01224548

COMPLETED NA 291 participants

Evaluation of Extended Wear Infusion Set (EWIS) in Patients With Type 1 Diabetes

Medtronic Diabetes

NCT04113694

COMPLETED NA 290 participants

Technologically Enhanced Coaching: A Program to Improve Diabetes Outcomes

VA Office of Research and Development

NCT01855399

COMPLETED NA 270 participants

Diabetes CKD Lifestyle Technology Study

NYU Langone Health

NCT02266823

COMPLETED Phase 2 265 participants

Sunshine 2 Study for Women With Diabetes

Loyola University

NCT01904032

COMPLETED Phase 4 262 participants

Preventing Depression Recurrence in Diabetes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00374426

COMPLETED NA 250 participants

Self-Monitoring of Blood Glucose Study#1: The Ability of People With Diabetes to Use OneTouch(R) Ultrasmart(tm)

LifeScan

NCT00333853

COMPLETED NA 247 participants

Improving Adherence to Prescribing Guidelines for Cholesterol Lowering in Hospitalized Diabetic Patients

Washington University School of Medicine

NCT01113099

COMPLETED Phase 3 244 participants

Improving Insulin Therapy With Enhanced Care Management

US Department of Veterans Affairs

NCT00320112

COMPLETED Phase 3 242 participants

Efficacy, Safety and Preference Study of a Insulin Pen PDS290 vs. a Novo Nordisk Marketed Insulin Pen in Diabetics

Novo Nordisk A/S

NCT00773279

COMPLETED NA 241 participants

Peer-Led Self-Management Support in "Real World" Clinical and Community Settings

University of Michigan

NCT01517919

COMPLETED 240 participants

A Study Comparing Skin Fluorescence to Coronary Artery Calcification

VeraLight

NCT00895427

COMPLETED 240 participants

Food Intake and Appetite in the Children of Mothers With Diabetes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00339313

COMPLETED Phase 3 239 participants

Can Group Visits Improve Outcomes of Veterans With Diabetes

US Department of Veterans Affairs

NCT00286741

COMPLETED NA 234 participants

Framingham State Food Study

Boston Children's Hospital

NCT02068885

COMPLETED NA 232 participants

Lifestyle Intervention in Overweight and Obese Pregnant Hispanic Women

University of Massachusetts, Amherst

NCT01868230

COMPLETED 228 participants

Cocoa, Polyphenols, and the Kidney in Healthy Subjects and in Subjects With Hypertension and Diabetes Mellitus

Brigham and Women's Hospital

NCT00639665

COMPLETED 225 participants

Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes

VA Office of Research and Development

NCT04587336

COMPLETED 225 participants

A Study of the Function of Hormones Present In Taste Buds

National Institute on Aging (NIA)

NCT00233298

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Phase Distribution

PhaseTrial count
Phase 1 23
Phase 2 13
Phase 3 37
Phase 4 18

Named interventions

Most-linked intervention names on Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

insulin degludec Drug
11 trials
Placebo Drug
10 trials
insulin glargine Drug
9 trials
insulin aspart Drug
9 trials
semaglutide Drug
7 trials
liraglutide Drug
6 trials
placebo Drug
6 trials
insulin detemir Drug
4 trials

US sites by state

Facility locations filed on Diabetes trials. A trial with sites in several states counts in each.

California 82 trials
Florida 59 trials
Maryland 39 trials
Georgia 38 trials
Massachusetts 35 trials
Texas 33 trials
New York 31 trials
Colorado 31 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Diabetes page

342 registered trials, 86 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes condition card totals 342 registered trials; most-linked intervention insulin degludec; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.