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ClinicalTrials.gov 86 recruiting now official registry

Diabetes clinical trials

86 of 342 indexed Diabetes trials are currently recruiting.

342 US clinical trials · 86 currently recruiting

Diabetes is the subject of 342 registered US clinical trials on ClinicalTrials.gov, 86 of them currently open to new participants. 55 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 41 of these trials.

The research picture

Diabetes has 342 registered US clinical trials, 86 of them open to new participants right now, about 25% of the total.

86
recruiting participants now
25%
of trials open to enrollment
55
in Phase 3–4 (later-stage)
41
top sponsor: Novo Nordisk A/S
Phase 123Phase 213Phase 337Phase 418

Active & Recent Trials

342 total, page 4 of 7

COMPLETED 509 participants

Evaluation of a Noninvasive Diabetes Screening Device in Subjects at Risk for Diabetes

VeraLight

NCT01080157

COMPLETED Phase 3 503 participants

Comparison of Insulin Detemir Morning, Insulin Detemir Evening and NPH Insulin Evening in Patients With Type 2 Diabetes

Novo Nordisk A/S

NCT00104182

COMPLETED Phase 3 467 participants

Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes

Novo Nordisk A/S

NCT01076647

COMPLETED Phase 3 465 participants

Comparison of NN5401 With Insulin Glargine, Both in Combination With Oral Antidiabetic Drugs, in Subjects With Type 2 Diabetes

Novo Nordisk A/S

NCT01045447

COMPLETED NA 460 participants

Healthy Eating and Active Living Taught at Home

Washington University School of Medicine

NCT01567033

COMPLETED Phase 3 458 participants

Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With Insulin

Novo Nordisk A/S

NCT01046110

COMPLETED Phase 3 435 participants

The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy

Novo Nordisk A/S

NCT01618162

COMPLETED NA 425 participants

Healthy.io Method Comparison & User Performance Study

Healthy.io

NCT02785445

COMPLETED 417 participants

DHS MIND Metabolomics

Wake Forest University Health Sciences

NCT03975309

COMPLETED 400 participants

Wound Assessment Using Spectral Imaging US

SpectralMD

NCT05415683

COMPLETED NA 400 participants

The ABC Planning Study: Diabetes and Cardiovascular Risks in Primary Care

The University of Texas Health Science Center at San Antonio

NCT00223340

COMPLETED NA 400 participants

The Health Access and Recovery Peer Program

Emory University

NCT01725815

COMPLETED NA 392 participants

The GoodNEWS Lifestyle Enhancement Program

University of Texas Southwestern Medical Center

NCT00669630

COMPLETED NA 381 participants

Therapeutic Stockings to Prevent Foot Ulcers

University of Texas Southwestern Medical Center

NCT01221194

COMPLETED NA 376 participants

Evaluation of a Ascensia ONYX NEXT Investigational Blood Glucose Monitoring System

Ascensia Diabetes Care

NCT02390167

COMPLETED Phase 3 373 participants

Comparison of Two Insulin Degludec Formulations in Subjects With Type 2 Diabetes Mellitus

Novo Nordisk A/S

NCT01364428

COMPLETED Phase 3 362 participants

A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes Mellitus

Novo Nordisk A/S

NCT01835431

COMPLETED NA 362 participants

Harnessing Health IT for Self-Management Support and Medication Activation in a Medicaid Health Plan

University of California, San Francisco

NCT00683020

COMPLETED NA 360 participants

Feasibility and Impact of "ABCs of Diabetes" Self-Management Education Program at an Urban Public Library

Medstar Health Research Institute

NCT00822471

COMPLETED NA 355 participants

Enhanced Quality in Primary Care for Elders With Diabetes and Dementia

NYU Langone Health

NCT03723707

COMPLETED NA 348 participants

A Helping Hand Among Low-Income Patients

University of Southern California

NCT02147522

COMPLETED Phase 3 346 participants

The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification

Novo Nordisk A/S

NCT01664247

COMPLETED NA 339 participants

Improving Diabetes Efforts Across Language and Literacy (IDEALL)

Agency for Healthcare Research and Quality (AHRQ)

NCT00214474

COMPLETED NA 338 participants

Growing Resilience in Wind River Indian Reservation

University of Wyoming

NCT02672748

COMPLETED Phase 2 319 participants

Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain

Lexicon Pharmaceuticals

NCT04455633

COMPLETED 310 participants

Family Genetics Health Education and Healthy Behaviors

National Human Genome Research Institute (NHGRI)

NCT01498276

COMPLETED NA 302 participants

Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease

University of Pennsylvania

NCT01900470

COMPLETED NA 302 participants

Men Together Making a Difference: Health Promotion for Black Men

University of Pennsylvania

NCT02572414

COMPLETED Phase 3 302 participants

Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus

Novo Nordisk A/S

NCT03086330

COMPLETED 300 participants

Racial/Ethnic Differences in Trust/Mistrust and Its Effect on Diabetes Outcomes

US Department of Veterans Affairs

NCT00383110

COMPLETED Phase 3 293 participants

Comparison of Biphasic Insulin Aspart 70/30 Versus Insulin Glargine in Subjects With Type 2 Diabetes

Novo Nordisk A/S

NCT00097877

COMPLETED NA 292 participants

Multicenter Worksite Nutrition Study

Physicians Committee for Responsible Medicine

NCT01224548

COMPLETED NA 291 participants

Evaluation of Extended Wear Infusion Set (EWIS) in Patients With Type 1 Diabetes

Medtronic Diabetes

NCT04113694

COMPLETED NA 290 participants

Technologically Enhanced Coaching: A Program to Improve Diabetes Outcomes

VA Office of Research and Development

NCT01855399

COMPLETED NA 270 participants

Diabetes CKD Lifestyle Technology Study

NYU Langone Health

NCT02266823

COMPLETED Phase 2 265 participants

Sunshine 2 Study for Women With Diabetes

Loyola University

NCT01904032

COMPLETED Phase 4 262 participants

Preventing Depression Recurrence in Diabetes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00374426

COMPLETED NA 250 participants

Self-Monitoring of Blood Glucose Study#1: The Ability of People With Diabetes to Use OneTouch(R) Ultrasmart(tm)

LifeScan

NCT00333853

COMPLETED NA 247 participants

Improving Adherence to Prescribing Guidelines for Cholesterol Lowering in Hospitalized Diabetic Patients

Washington University School of Medicine

NCT01113099

COMPLETED Phase 3 244 participants

Improving Insulin Therapy With Enhanced Care Management

US Department of Veterans Affairs

NCT00320112

COMPLETED Phase 3 242 participants

Efficacy, Safety and Preference Study of a Insulin Pen PDS290 vs. a Novo Nordisk Marketed Insulin Pen in Diabetics

Novo Nordisk A/S

NCT00773279

COMPLETED NA 241 participants

Peer-Led Self-Management Support in "Real World" Clinical and Community Settings

University of Michigan

NCT01517919

COMPLETED 240 participants

A Study Comparing Skin Fluorescence to Coronary Artery Calcification

VeraLight

NCT00895427

COMPLETED 240 participants

Food Intake and Appetite in the Children of Mothers With Diabetes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00339313

COMPLETED Phase 3 239 participants

Can Group Visits Improve Outcomes of Veterans With Diabetes

US Department of Veterans Affairs

NCT00286741

COMPLETED NA 234 participants

Framingham State Food Study

Boston Children's Hospital

NCT02068885

COMPLETED NA 232 participants

Lifestyle Intervention in Overweight and Obese Pregnant Hispanic Women

University of Massachusetts, Amherst

NCT01868230

COMPLETED 228 participants

Cocoa, Polyphenols, and the Kidney in Healthy Subjects and in Subjects With Hypertension and Diabetes Mellitus

Brigham and Women's Hospital

NCT00639665

COMPLETED 225 participants

Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes

VA Office of Research and Development

NCT04587336

COMPLETED 225 participants

A Study of the Function of Hormones Present In Taste Buds

National Institute on Aging (NIA)

NCT00233298

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Phase Distribution

PhaseTrial count
Phase 1 23
Phase 2 13
Phase 3 37
Phase 4 18

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Diabetes Trial Landscape

342 indexed Diabetes studies · 86 recruiting (25%).

Phase mix: 55 late (III/IV) vs 36 early (I/II).

Top sponsor: Novo Nordisk A/S (41 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Diabetes?

PlainTrial tracks 342 US clinical trials for Diabetes, of which 86 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Diabetes?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.