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2026 data Public-data reference. official source

Cytomegalovirus Infections

Open-data reference.

25 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING 100 participants

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

University of Massachusetts, Worcester

NCT06522880

RECRUITING Phase 3 90 participants

Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients

University of Wisconsin, Madison

NCT06407232

RECRUITING Phase 2 80 participants

Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

University of Pennsylvania

NCT06066957

RECRUITING Phase 1 36 participants

R-MVST Cells for Treatment of Viral Infections

Columbia University

NCT05183490

RECRUITING Phase 4 25 participants

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

Tufts Medical Center

NCT05626530

RECRUITING Phase 1 25 participants

Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity

Jessie L. Alexander

NCT06909110

RECRUITING Phase 2 20 participants

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

New York Medical College

NCT03266640

RECRUITING Early Phase 1 20 participants

T Cell Therapy of Opportunistic Cytomegalovirus Infection

Mari Dallas

NCT02982902

RECRUITING Phase 1 18 participants

R-MVST Cells for Treatment of Viral Infections in Children and Young Adults

Columbia University

NCT06926894

ACTIVE NOT RECRUITING Phase 1 52 participants

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

Pediatric Transplantation & Cellular Therapy Consortium

NCT03475212

ACTIVE NOT RECRUITING Phase 1 25 participants

Viral Specific T-Lymphocytes to Treat Adenovirus or CMV

Jessie L. Alexander

NCT04364178

COMPLETED Phase 3 1,200 participants

A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001038

COMPLETED 1,000 participants

A Retrospective Chart Review Study of Gene-Eden-VIR/Novirin

The Center for the Biology of Chronic Disease

NCT02715752

COMPLETED Phase 3 681 participants

Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients

Shire

NCT00411645

COMPLETED Phase 3 505 participants

The Safety and Effectiveness of Adefovir Dipivoxil in the Treatment of HIV-Infected Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001082

COMPLETED Phase 1 339 participants

A Study of Safety and Immune Response to Different Doses of a Cytomegalovirus Vaccine in Healthy Adults

GlaxoSmithKline

NCT05089630

COMPLETED Phase 3 130 participants

A Phase III Study to Evaluate the Safety and Efficacy of Ganciclovir (Dihydroxypropoxymethyl Guanine [DHPG]) Treatment of Symptomatic Central Nervous System (CNS) Congenital Cytomegalovirus (CMV) Infections.

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001100

COMPLETED Phase 2 122 participants

A Study of MCMV5322A/MCMV3068A for the Prevention of Cytomegalovirus Disease in High-Risk Kidney Allograft Recipients

Genentech

NCT01753167

COMPLETED 111 participants

Evaluation of the Artus® CMV PCR Test

QIAGEN Gaithersburg

NCT01034709

COMPLETED Phase 2 90 participants

Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplex®)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05099965

COMPLETED Phase 2 80 participants

Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001890

COMPLETED Phase 2 38 participants

Accelerated Immunization to Induce Cytomegalovirus Immunity in Stem Cell Donors

National Heart, Lung, and Blood Institute (NHLBI)

NCT00353977

COMPLETED NA 30 participants

A Study of Lobucavir in Patients With AIDS

Bristol-Myers Squibb

NCT00002352

COMPLETED Phase 1 24 participants

A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine

Hoffmann-La Roche

NCT00002096

COMPLETED 20 participants

Immune Response to Cytomegalovirus

National Heart, Lung, and Blood Institute (NHLBI)

NCT00034437

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 6
Phase 3 5
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cytomegalovirus Infections Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Cytomegalovirus Infections, and 9 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Cytomegalovirus Infections shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 14 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Cytomegalovirus Infections is led by National Institute of Allergy and Infectious Diseases (NIAID) with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cytomegalovirus Infections?

PlainTrial tracks 25 US clinical trials for Cytomegalovirus Infections, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cytomegalovirus Infections?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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