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ClinicalTrials.gov 9 recruiting now early-phase tilt

Acute Lymphocytic Leukemia: early-phase trial registry

9 of 25 indexed Acute Lymphocytic Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 9 currently recruiting · #652 of 28,707 conditions by registered trial count

Acute Lymphocytic Leukemia: 25 US clinical trials tracked, 9 recruiting.

Acute Lymphocytic Leukemia is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 2 of these trials.

Enrollment posture brief

Registry condition acute-lymphocytic-leukemia

OPEN 9 | RECR 36% | LATE 0 | EARLY 22 | RANK #652 | SPON 2

Nearest open-share peer: Cannabis (36% recruiting · 25 trials)

Amblyopia52%Alpha-1 Antitrypsin Deficien48%Alcohol Use40%Alcohol-Related Disorders36%Acute Lymphocytic Leukem (th…36%
Open-enrollment share among volume-matched conditions near Acute Lymphocytic Leukemia

Acute Lymphocytic Leukemia lists 9 open slots (36% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Lymphocytic Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Lymphocytic Leukemia is recruiting below its size-band peers.

    9 of 25 indexed trials (36%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Acute Lymphocytic Leukemia trials is spread across many organizations.

    Washington University School of Medicine accounts for 2 of 25 trials (8%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Acute Lymphocytic Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 40 among the 25 trials that report a genuine target (sentinel values excluded). 21 of those (84%) plan for fewer than 100 participants.

  4. Acute Lymphocytic Leukemia research is mostly interventional.

    23 interventional and 2 observational studies make up this index (92% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 114Phase 28

Open and recent trials

25 total, page 1 of 1

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING Phase 1 126 participants

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT05442515

RECRUITING Phase 1 100 participants

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Newave Pharmaceutical

NCT04771572

RECRUITING Phase 1 64 participants

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Baylor College of Medicine

NCT01853631

RECRUITING Phase 1 60 participants

Pilot Imaging Study of Leukemia

University of Oklahoma

NCT03633955

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING Phase 1 44 participants

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

Leland Metheny

NCT03104491

RECRUITING Phase 2 36 participants

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Case Comprehensive Cancer Center

NCT06904482

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

ACTIVE NOT RECRUITING Phase 1 42 participants

Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy

Washington University School of Medicine

NCT05044039

ACTIVE NOT RECRUITING Phase 2 22 participants

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Masonic Cancer Center, University of Minnesota

NCT03674411

ACTIVE NOT RECRUITING Phase 1 19 participants

In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

Memorial Sloan Kettering Cancer Center

NCT01430390

ACTIVE NOT RECRUITING Phase 1 14 participants

CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL

Baylor College of Medicine

NCT00586391

COMPLETED Phase 1 134 participants

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT02315612

COMPLETED Phase 1 55 participants

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Washington University School of Medicine

NCT03755414

COMPLETED Phase 2 51 participants

INCB018424 in Patients With Advanced Hematologic Malignancies

M.D. Anderson Cancer Center

NCT00674479

COMPLETED Phase 1 40 participants

A Study of Low-Dose Decitabine in Relapsed or Refractory Acute Lymphocytic Leukemia (ALL)

M.D. Anderson Cancer Center

NCT00349596

COMPLETED NA 40 participants

Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT

University of Virginia

NCT04629430

COMPLETED Phase 2 40 participants

HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies

St. Jude Children's Research Hospital

NCT00145626

COMPLETED Phase 2 36 participants

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

University of California, San Francisco

NCT00516152

COMPLETED Phase 2 25 participants

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Northside Hospital

NCT02581007

COMPLETED Phase 1 18 participants

Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemia

Tara Lin

NCT02914977

COMPLETED Phase 2 14 participants

Experimental Bone Marrow Transplant Protocol

National Heart, Lung, and Blood Institute (NHLBI)

NCT00061581

COMPLETED Phase 1 14 participants

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

Case Comprehensive Cancer Center

NCT02129582

COMPLETED Phase 1 10 participants

Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood Cancers

ViaCell

NCT00089596

Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 8

Named interventions

Most-linked intervention names on Acute Lymphocytic Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Drug
2 trials
Cyclophosphamide Drug
2 trials
myeloid progenitor cell transplantation Procedure
1 trials
Isolex 300i Stem Cell Selection Device
1 trials
Busulfan/Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF Drug
1 trials
Allogeneic stem cell transplantation Procedure
1 trials
Miltenyi Biotec CliniMACS Device
1 trials
Chemotherapy and antibodies Drug
1 trials

US sites by state

Facility locations filed on Acute Lymphocytic Leukemia trials. A trial with sites in several states counts in each.

Texas 6 trials
Ohio 5 trials
New York 3 trials
Maryland 3 trials
North Carolina 2 trials
Missouri 2 trials
Minnesota 2 trials
Massachusetts 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Lymphocytic Leukemia page

25 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Lymphocytic Leukemia condition card totals 25 registered trials; most-linked intervention Fludarabine; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.