Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 9 recruiting now official registry

Acute Lymphocytic Leukemia clinical trials

Every US clinical trial registered for Acute Lymphocytic Leukemia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

25 US clinical trials · 9 currently recruiting

The research picture

Acute Lymphocytic Leukemia has 25 registered US clinical trials, 9 of them open to new participants right now — about 36% of the total.

9
recruiting participants now
36%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Washington University School of Medicine

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING Phase 1 126 participants

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT05442515

RECRUITING Phase 1 100 participants

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Newave Pharmaceutical

NCT04771572

RECRUITING Phase 1 64 participants

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Baylor College of Medicine

NCT01853631

RECRUITING Phase 1 60 participants

Pilot Imaging Study of Leukemia

University of Oklahoma

NCT03633955

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING Phase 1 44 participants

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

Leland Metheny

NCT03104491

RECRUITING Phase 2 36 participants

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Case Comprehensive Cancer Center

NCT06904482

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

ACTIVE NOT RECRUITING Phase 1 42 participants

Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy

Washington University School of Medicine

NCT05044039

ACTIVE NOT RECRUITING Phase 2 22 participants

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Masonic Cancer Center, University of Minnesota

NCT03674411

ACTIVE NOT RECRUITING Phase 1 19 participants

In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

Memorial Sloan Kettering Cancer Center

NCT01430390

ACTIVE NOT RECRUITING Phase 1 14 participants

CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL

Baylor College of Medicine

NCT00586391

COMPLETED Phase 1 134 participants

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT02315612

COMPLETED Phase 1 55 participants

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Washington University School of Medicine

NCT03755414

COMPLETED Phase 2 51 participants

INCB018424 in Patients With Advanced Hematologic Malignancies

M.D. Anderson Cancer Center

NCT00674479

COMPLETED Phase 1 40 participants

A Study of Low-Dose Decitabine in Relapsed or Refractory Acute Lymphocytic Leukemia (ALL)

M.D. Anderson Cancer Center

NCT00349596

COMPLETED NA 40 participants

Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT

University of Virginia

NCT04629430

COMPLETED Phase 2 40 participants

HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies

St. Jude Children's Research Hospital

NCT00145626

COMPLETED Phase 2 36 participants

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

University of California, San Francis

NCT00516152

COMPLETED Phase 2 25 participants

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Northside Hospital

NCT02581007

COMPLETED Phase 1 18 participants

Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemia

Tara Lin

NCT02914977

COMPLETED Phase 2 14 participants

Experimental Bone Marrow Transplant Protocol

National Heart, Lung, and Blood Institute (NHLBI)

NCT00061581

COMPLETED Phase 1 14 participants

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

Case Comprehensive Cancer Center

NCT02129582

COMPLETED Phase 1 10 participants

Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood Cancers

ViaCell

NCT00089596

Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Lymphocytic Leukemia Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Acute Lymphocytic Leukemia, and 9 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Acute Lymphocytic Leukemia shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 22 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Acute Lymphocytic Leukemia is led by Washington University School of Medicine with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Lymphocytic Leukemia?

PlainTrial tracks 25 US clinical trials for Acute Lymphocytic Leukemia, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Lymphocytic Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →