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RECRUITING Phase 2

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

NCT03266640 · View on ClinicalTrials.gov ↗

Study Summary

CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: FDA OOPD

Interventions

  • DRUG viral specific cytotoxic t-lymphocytes

Study Locations (9)

California

  • Children's Hospital Los Angeles — Los Angeles
  • University of California San Francisco — San Francisco

Indiana

  • Indiana University — Indianapolis

Maryland

  • Johns Hopkins — Baltimore

Missouri

  • Washington University — St Louis

New York

  • New York Medical College — Valhalla

Ohio

  • Nationwide Children's Hosptial — Columbus

Pennsylvania

  • Children's Hospital of Pennsylvania — Philadelphia

Wisconsin

  • Medical College of Wisconsin/Children's Hospital of Wisconsin — Milwaukee

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2018-11-01
Est. Completion 2027-12-31
Phase Phase 2

Sponsor

New York Medical College

50 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03266640

The ClinicalTrials.gov registry entry for NCT03266640 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is New York Medical College, which has 50 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Cytomegalovirus Infections appearing as the primary indexed condition, and to 1 intervention — of which viral specific cytotoxic t-lymphocytes is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03266640 reports 9 study locations spanning 8 distinct geographic areas — top geographies include California, Indiana, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03266640 about?

NCT03266640 is a clinical study titled "Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)". CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary...

What is the current status of trial NCT03266640?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2018-11-01. Estimated completion is 2027-12-31.

What conditions does trial NCT03266640 study?

This clinical trial studies the following conditions: Cytomegalovirus Infections, Primary Immune Deficiency Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03266640?

The interventions under investigation include: viral specific cytotoxic t-lymphocytes (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03266640?

This trial is sponsored by New York Medical College, which has 50 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03266640 being conducted?

This trial has 9 study locations across California, Indiana, Maryland, Missouri, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial