Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Alcohol-Related Disorders

Open-data reference.

21 US clinical trials · 8 currently recruiting

Active & Recent Trials

RECRUITING 1,500 participants

COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT04391816

RECRUITING 1,000 participants

Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02108080

RECRUITING NA 400 participants

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Emory University

NCT05910580

RECRUITING Phase 3 270 participants

Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease

VA Office of Research and Development

NCT07039175

RECRUITING Phase 1 63 participants

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

NCT06070649

RECRUITING NA 40 participants

External Facilitation to Increase Prescribing of AUD Medications in the Psychiatric Setting

University of Maryland, Baltimore

NCT07053098

RECRUITING NA 36 participants

Feasibility of the 5-Step Method in the U.S.

Villanova University

NCT06565429

RECRUITING Phase 1 24 participants

Diclofenac Dose Response Study

University of Maryland, Baltimore

NCT06636227

ACTIVE NOT RECRUITING NA 13,000 participants

Digital Treatments for Opioids and Other Substance Use Disorders in Primary Care

Kaiser Permanente

NCT05160233

ACTIVE NOT RECRUITING NA 470 participants

TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

University of New Mexi

NCT06074341

ACTIVE NOT RECRUITING NA 360 participants

Addressing Barriers to Care for Substance Use Disorder Trial

Kaiser Permanente

NCT06729957

ACTIVE NOT RECRUITING NA 74 participants

Addressing Barriers to Care for Substance Use Disorder Pilot Study

Kaiser Permanente

NCT06317987

COMPLETED Phase 2 208 participants

Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1

University of Pennsylvania

NCT00142844

COMPLETED NA 164 participants

Adaptive Interventions for Problem Drinkers

Northwell Health

NCT02511808

COMPLETED NA 113 participants

Helping College Students With ADHD Lead Healthier Lifestyles

University of Maryland, College Park

NCT02829970

COMPLETED NA 88 participants

Substance Use Treatment and Recovery Team (START)

RAND

NCT04314648

COMPLETED NA 60 participants

Michigan Alcohol Improvement Network- Alcohol Reduction and Treatment Trial

University of Michigan

NCT04473482

COMPLETED Phase 1 38 participants

Exercise as Alcohol Use Disorders Intervention for Non-Treatment Seeking Adults

St. Louis University

NCT01399554

COMPLETED Phase 1 27 participants

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Northwell Health

NCT02885311

COMPLETED Phase 1 14 participants

A Novel Compound for Alcoholism Treatment

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02039349

COMPLETED Phase 2

Disulfiram for Cocaine-Alcohol Abuse - 3

Yale University

NCT00000278

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 2
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alcohol-Related Disorders Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Alcohol-Related Disorders, and 8 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Alcohol-Related Disorders shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Alcohol-Related Disorders is led by Kaiser Permanente with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alcohol-Related Disorders?

PlainTrial tracks 21 US clinical trials for Alcohol-Related Disorders, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alcohol-Related Disorders?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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