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NCT03475212 · ClinicalTrials.gov registry record · Phase 1
Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation
A Phase 1 study of Cytomegalovirus Infections and Adenovirus Infection, sponsored by Pediatric Transplantation & Cellular Therapy Consortium.
- Active
- Registry status
- Phase 1
- Development phase
- 52
- Enrollment target
- 20
- Study locations
NCT03475212 is a Phase 1 study of Cytomegalovirus Infections and Adenovirus Infection that is active but no longer recruiting, run by Pediatric Transplantation & Cellular Therapy Consortium. The registered enrollment target is 52 participants, below the 200-participant average among 24 other Cytomegalovirus Infections trials with a reported enrollment target (74% lower). The trial reports 20 study locations across 13 states.
The verdict
NCT03475212, a Phase 1 study of Cytomegalovirus Infections and Adenovirus Infection, is active but no longer recruiting, sponsored by Pediatric Transplantation & Cellular Therapy Consortium.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 52 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate whether virus-specific T cell lines (VSTs) are safe and can effectively control three viruses (EBV, CMV, and adenovirus) in patients who have had a stem cell transplant and also in patients that have a primary immunodeficiency disorder with no prior stem cell transplant.
Conditions Studied
Interventions
- BIOLOGICAL Virus Specific T-cell (VST) infusion
Study Locations (20)
California
- City of Hope - Duarte
- University of California, Los Angeles - Los Angeles
- Children's Hospital Los Angeles - Los Angeles
- Stanford Lucile Packard Children's Hospital - Palo Alto
- UCSF Medical Center - San Francisco
Massachusetts
- Tufts Medical Center - Boston
- Dana-Farber Cancer Institute/ Boston Children's Hospital - Boston
Michigan
- University of Michigan - Ann Arbor
- Spectrum Health - Helen DeVos Children's Hospital - Grand Rapids
New York
- Roswell Park Comprehensive Cancer Center - Buffalo
- Columbia University Medical Center - New York
Arizona
- Phoenix Children's Hospital - Phoenix
Colorado
- Children's Hospital Colorado - Aurora
Connecticut
- Yale - New Haven
District of Columbia
- Children's National Medical Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2018-06-20 |
| Est. Completion | 2025-06-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03475212
The ClinicalTrials.gov registry entry for NCT03475212 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 200-participant average among 24 other Cytomegalovirus Infections trials with a reported enrollment target (74% lower). The listed sponsor is Pediatric Transplantation & Cellular Therapy Consortium, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Cytomegalovirus Infections appearing as the primary indexed condition, and to 1 intervention - of which Virus Specific T-cell (VST) infusion is the first listed.
NCT03475212 reports 20 study locations spanning 13 distinct geographic areas - top geographies include California, Massachusetts, Michigan.
Frequently Asked Questions
What is clinical trial NCT03475212 about?
NCT03475212 is a clinical study titled "Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation". The purpose of this study is to evaluate whether virus-specific T cell lines (VSTs) are safe and can effectively control three viruses (EBV, CMV, and adenovirus) in patients who have had a stem cell transplant and also in patients that have a primary immunodeficiency disorder with no prior stem cell...
What is the current status of trial NCT03475212?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2018-06-20. Estimated completion is 2025-06-30.
What conditions does trial NCT03475212 study?
This clinical trial studies the following conditions: Cytomegalovirus Infections, Adenovirus Infection, EBV Infection.
What interventions are being tested in trial NCT03475212?
The interventions under investigation include: Virus Specific T-cell (VST) infusion (BIOLOGICAL).
Who is sponsoring clinical trial NCT03475212?
This trial is sponsored by Pediatric Transplantation & Cellular Therapy Consortium, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03475212 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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