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RECRUITING Phase 4

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

NCT05626530 · View on ClinicalTrials.gov ↗

Study Summary

This is a research study to test the tolerability and clinical effectiveness of the study drug, Letermovir (LET), when used as secondary prophylaxis following treatment of Cytomegalovirus (CMV) infection and disease in a solid organ transplant recipient. This study is an open label trial in which Letermovir will be prescribed to prevent the recurrence of CMV infection and disease in a solid organ transplant recipient following treatment of CMV infection or disease.

Interventions

  • DRUG Letermovir

Study Locations (1)

Massachusetts

  • Tufts Medical Center-Division of Geographic Medicine and Infectious Diseases — Boston

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2023-02-02
Est. Completion 2025-12-15
Phase Phase 4

Sponsor

Tufts Medical Center

132 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05626530

The ClinicalTrials.gov registry entry for NCT05626530 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Tufts Medical Center, which has 132 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Cytomegalovirus Infections appearing as the primary indexed condition, and to 1 intervention — of which Letermovir is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05626530 reports 1 study location spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05626530 about?

NCT05626530 is a clinical study titled "Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients". This is a research study to test the tolerability and clinical effectiveness of the study drug, Letermovir (LET), when used as secondary prophylaxis following treatment of Cytomegalovirus (CMV) infection and disease in a solid organ transplant recipient. This study is an open label trial in which L...

What is the current status of trial NCT05626530?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 25 participants. The study started on 2023-02-02. Estimated completion is 2025-12-15.

What conditions does trial NCT05626530 study?

This clinical trial studies the following conditions: Cytomegalovirus Infections, Neutropenia, Infection in Solid Organ Transplant Recipients, Antiviral Toxicity. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05626530?

The interventions under investigation include: Letermovir (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05626530?

This trial is sponsored by Tufts Medical Center, which has 132 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05626530 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial