Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cannabis clinical trials
Every US clinical trial registered for Cannabis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
25 US clinical trials · 9 currently recruiting
The research picture
Cannabis has 25 registered US clinical trials, 9 of them open to new participants right now — about 36% of the total.
- 9
- recruiting participants now
- 36%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Yale University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Cannabis' Impact on Alcohol Consumption
Brown University
NCT05389930
Cannabis, HIV and Mental Processing Systems
Washington University School of Medicine
NCT05430490
Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Wake Forest University Health Sciences
NCT04810858
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans
Yale University
NCT02781519
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II
Yale University
NCT04704271
Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV
University of California, San Diego
NCT05514899
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 3
L. Cinnamon Bidwell
NCT06669585
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
University of California, San Francis
NCT05999383
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I
Yale University
NCT02811510
Cannabinoids, Learning, and Memory
Yale University
NCT02407808
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
Yale University
NCT02710097
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition
Yale University
NCT02404688
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III
Yale University
NCT02710331
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I
Yale University
NCT02709954
THC Memory & Reward Learning Pilot
Hartford Hospital
NCT05116527
Intervening to Prevent Youth Access to Marijuana Phase II
Klein Buendel
NCT03073291
Web-based vs In-person Personalized Feedback Intervention for Comorbid Substance Use and Disordered Gambling
University of Washington
NCT01529047
Efficacy of Inhaled Cannabis for Acute Migraine Treatment
University of California, San Diego
NCT04360044
Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)
Duke University
NCT04567238
Pain Inflammation and Cannabis in HIV
Montefiore Medical Center
NCT05554146
Families With Substance Use and Psychosis: A Pilot Study
Mclean Hospital
NCT04284813
Impact of Reduced Cannabis Use on Functional Outcomes
Duke University
NCT03681353
Laboratory Smoking of Marijuana "Blunts"
Battelle Memorial Institute
NCT03546790
Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain
University of California, San Diego
NCT03099005
Feasibility Trial of rTMS for Cannabis Use Disorder
Medical University of South Carolina
NCT03538288
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cannabis Trial Landscape
ClinicalTrials.gov lists 25 US studies indexed under Cannabis, and 9 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cannabis shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cannabis is led by Yale University with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cannabis?
PlainTrial tracks 25 US clinical trials for Cannabis, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cannabis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.