Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Alcohol Use

Open-data reference.

25 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING NA 1,000 participants

Get Better Together: Relationship Education For Military Couples

Henry M. Jackson Foundation for the Advancement of Military Medicine

NCT07096271

RECRUITING NA 615 participants

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

Indiana University

NCT06593652

RECRUITING NA 456 participants

Stress and Resilience

University of Washington

NCT06457841

RECRUITING Phase 2 160 participants

Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

Yale University

NCT03764098

RECRUITING NA 120 participants

Wellness, Alcohol, Vitals, and Emotions

University of New Mexi

NCT06982443

RECRUITING NA 120 participants

The Less is More Study

University of Florida

NCT05153811

RECRUITING NA 100 participants

Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making

Mark J Rzeszutek, PhD

NCT06845761

RECRUITING NA 90 participants

Multi-Component Breath Alcohol Intervention Phase 3

Northeastern University

NCT06994962

RECRUITING Phase 1 63 participants

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

NCT06070649

RECRUITING NA 60 participants

Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioid Agonist Treatment

University of Notre Dame

NCT07342504

ACTIVE NOT RECRUITING NA 333 participants

CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)

University of Washington

NCT06648395

ACTIVE NOT RECRUITING NA 115 participants

Multi-Component Breath Alcohol Intervention

Northeastern University

NCT06124898

COMPLETED NA 1,072 participants

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

Johns Hopkins Bloomberg School of Public Health

NCT02904629

COMPLETED NA 737 participants

Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use

Mark J Rzeszutek, PhD

NCT07010601

COMPLETED NA 294 participants

Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care

RAND

NCT01797835

COMPLETED Phase 2 200 participants

Oxytocin, Alcohol Craving, and Intimate Partner Aggression

Medical University of South Carolina

NCT03046836

COMPLETED NA 174 participants

Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings

Hunter College of City University of New York

NCT02390908

COMPLETED NA 112 participants

Impaired Risk Awareness During Intoxication in DUI Offenders

Mark Fillmore

NCT05247788

COMPLETED NA 97 participants

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Treatment Research Institute

NCT02059005

COMPLETED 77 participants

Alcohol and Cannabis Co-Use and the Gut-Brain Axis

University of Colorado, Denver

NCT04998006

COMPLETED NA 65 participants

Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood

Johns Hopkins Bloomberg School of Public Health

NCT03900312

COMPLETED NA 60 participants

Development and Testing of a Smartphone Application to Reduce Substance Use and Sexual Risk Among Homeless Young Adults

New York State Psychiatric Institute

NCT02530645

COMPLETED NA 50 participants

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

University of Michigan

NCT03855410

COMPLETED NA 49 participants

Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction

Treatment Research Institute

NCT02378181

COMPLETED Phase 2

ED Intervention to Reduce Risky Behaviors in Drivers

Centers for Disease Control and Prevention

NCT00164294

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alcohol Use Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Alcohol Use, and 10 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Alcohol Use shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Alcohol Use is led by Treatment Research Institute with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alcohol Use?

PlainTrial tracks 25 US clinical trials for Alcohol Use, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alcohol Use?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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