Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 10 recruiting now early-phase tilt

Alcohol Use: early-phase trial registry

10 of 25 indexed Alcohol Use trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 10 currently recruiting · #652 of 28,707 conditions by registered trial count

Alcohol Use: 25 US clinical trials tracked, 10 recruiting.

Alcohol Use is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Treatment Research Institute, running 2 of these trials.

Enrollment posture brief

Registry condition alcohol-use

OPEN 10 | RECR 40% | LATE 0 | EARLY 4 | RANK #652 | SPON 2

Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)

Amblyopia52%Alpha-1 Antitrypsin Deficien48%Alcohol Use (this)40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%
Open-enrollment share among volume-matched conditions near Alcohol Use

Alcohol Use lists 10 open slots (40% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Alcohol Use on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Alcohol Use recruits in line with its size-band peers.

    10 of 25 indexed trials (40%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Alcohol Use trials is spread across many organizations.

    Treatment Research Institute accounts for 2 of 25 trials (8%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Typical Alcohol Use enrolment sits around 120 participants.

    Median target enrolment is 120 among the 24 trials that report a genuine target (sentinel values excluded). 9 of those (37.5%) plan for fewer than 100 participants.

  4. Alcohol Use research is mostly interventional.

    24 interventional and 1 observational studies make up this index (96% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23

Open and recent trials

25 total, page 1 of 1

RECRUITING NA 1,000 participants

Get Better Together: Relationship Education For Military Couples

Henry M. Jackson Foundation for the Advancement of Military Medicine

NCT07096271

RECRUITING NA 615 participants

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

Indiana University

NCT06593652

RECRUITING NA 456 participants

Stress and Resilience

University of Washington

NCT06457841

RECRUITING Phase 2 160 participants

Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

Yale University

NCT03764098

RECRUITING NA 120 participants

Wellness, Alcohol, Vitals, and Emotions

University of New Mexi

NCT06982443

RECRUITING NA 120 participants

The Less is More Study

University of Florida

NCT05153811

RECRUITING NA 100 participants

Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making

Mark J Rzeszutek, PhD

NCT06845761

RECRUITING NA 90 participants

Multi-Component Breath Alcohol Intervention Phase 3

Northeastern University

NCT06994962

RECRUITING Phase 1 63 participants

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

NCT06070649

RECRUITING NA 60 participants

Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioid Agonist Treatment

University of Notre Dame

NCT07342504

ACTIVE NOT RECRUITING NA 333 participants

CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)

University of Washington

NCT06648395

ACTIVE NOT RECRUITING NA 115 participants

Multi-Component Breath Alcohol Intervention

Northeastern University

NCT06124898

COMPLETED NA 1,072 participants

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

Johns Hopkins Bloomberg School of Public Health

NCT02904629

COMPLETED NA 737 participants

Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use

Mark J Rzeszutek, PhD

NCT07010601

COMPLETED NA 294 participants

Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care

RAND

NCT01797835

COMPLETED Phase 2 200 participants

Oxytocin, Alcohol Craving, and Intimate Partner Aggression

Medical University of South Carolina

NCT03046836

COMPLETED NA 174 participants

Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings

Hunter College of City University of New York

NCT02390908

COMPLETED NA 112 participants

Impaired Risk Awareness During Intoxication in DUI Offenders

Mark Fillmore

NCT05247788

COMPLETED NA 97 participants

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Treatment Research Institute

NCT02059005

COMPLETED 77 participants

Alcohol and Cannabis Co-Use and the Gut-Brain Axis

University of Colorado, Denver

NCT04998006

COMPLETED NA 65 participants

Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood

Johns Hopkins Bloomberg School of Public Health

NCT03900312

COMPLETED NA 60 participants

Development and Testing of a Smartphone Application to Reduce Substance Use and Sexual Risk Among Homeless Young Adults

New York State Psychiatric Institute

NCT02530645

COMPLETED NA 50 participants

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

University of Michigan

NCT03855410

COMPLETED NA 49 participants

Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction

Treatment Research Institute

NCT02378181

COMPLETED Phase 2

ED Intervention to Reduce Risky Behaviors in Drivers

Centers for Disease Control and Prevention

NCT00164294

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3

Named interventions

Most-linked intervention names on Alcohol Use records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Lower tech facilitation Behavioral
2 trials
Motivational interview and psychoeducation on blood/breath alcohol concentration Behavioral
2 trials
Alcohol-related mobile health technologies Device
2 trials
Health Education Toolkit Behavioral
1 trials
Blood alcohol concentration (BAC) discrimination training for controls Behavioral
1 trials
Performance feedback training Behavioral
1 trials
Blood alcohol concentration (BAC) discrimination training Behavioral
1 trials
Wait-list PLUS intervention Behavioral
1 trials

US sites by state

Facility locations filed on Alcohol Use trials. A trial with sites in several states counts in each.

Pennsylvania 3 trials
Kentucky 3 trials
Washington 2 trials
New York 2 trials
Massachusetts 2 trials
Indiana 2 trials
Connecticut 2 trials
Arizona 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Alcohol Use page

25 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Use condition card totals 25 registered trials; most-linked intervention Lower tech facilitation; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.