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Coronary Artery Disease clinical trials
57 of 220 indexed Coronary Artery Disease trials are currently recruiting.
220 US clinical trials · 57 currently recruiting
Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.
The research picture
Coronary Artery Disease has 220 registered US clinical trials, 57 of them open to new participants right now, about 26% of the total.
- 57
- recruiting participants now
- 26%
- of trials open to enrollment
- 42
- in Phase 3–4 (later-stage)
- 17
- top sponsor: University of Florida
Active & Recent Trials
220 total, page 4 of 5
Comparing TR Band to Statseal in Conjunction With TR Band
VA Long Beach Healthcare System
NCT03028025
Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)
Johns Hopkins University
NCT00353795
Evaluation Using Computed Tomography Angiography (CTA) to Investigate and Detect Atherosclerotic Graft Disease (ELUCIDATE)
Corewell Health East
NCT00580008
Sapphire 3 CTO Study
OrbusNeich
NCT06358508
Familiarization and Safety Study of PB127 Ultrasound Contrast Agent
Point Biomedical
NCT00594698
Stress CT Perfusion in Patients With Chest Pain
University of Chicago
NCT01969916
Left Versus Right Radial Artery and Radiation Exposure in Patients With Predictors of Trans-radial Failure
NYU Langone Health
NCT01707524
Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)
Shockwave Medical
NCT05966662
Effect of Evolocumab on Coronary Plaque Characteristics
Annapoorna Kini
NCT04710368
Age and Endothelial Progenitor Cell Mobilization
Emory University
NCT00585949
Cardiovascular Outcomes Of Diet Counseling
The Camelot Foundation
NCT00324545
Secondary Prevention After Coronary Bypass Surgery
Jeffrey Kramer, MD
NCT00843089
Myocardial Ischemia and Transfusion Pilot
Rutgers, The State University of New Jersey
NCT01167582
Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent
Marc Sakwa, MD
NCT01681095
Abbott Next Generation Drug Eluting Stent 48mm Study
Abbott Medical Devices
NCT04282148
Ticagrelor With and Without Aspirin in Patients With Diabetes Mellitus
University of Florida
NCT04484259
Rapid Stress/Rest Single-Day Tc-99m Sestamibi Myocardial Single Photon Emission Computed Tomography
St. Luke's-Roosevelt Hospital Center
NCT01434641
Comparing Blood Loss, RBC Transfusions and Inflammatory Marker Changes Among Methods of CPB
Baylor Research Institute
NCT01083914
Vegan vs AHA Diet on Inflammation and Glucometabolic Profile in Patients With CAD
NYU Langone Health
NCT02135939
Vitamin D Repletion in Coronary Artery Disease
Seth I. Sokol, M.D.
NCT01570309
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions in Small Vessels
Boston Scientific Corporation
NCT01498692
AngioSculpt® Coronary Bifurcation Study
AngioScore
NCT00686647
Aspirin Resistance in Coronary Artery Disease
Vanderbilt University
NCT00753935
Reduction in YEllow Plaque by Aggressive Lipid LOWering Therapy
Annapoorna Kini
NCT01567826
Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease
University of Florida
NCT02287909
Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease
Johns Hopkins University
NCT04272060
Evaluation of Pharmacist Interventions in Lipid Management for Secondary Prevention
Wake Forest University Health Sciences
NCT06647238
HCR vs. CABG Study
Emory University
NCT02892474
Observational Study of the Association Between Periodontal Disease and Cardiovascular Disease
Texas Tech University Health Sciences Center
NCT02177591
Reducing Radioisotope Dose: the Half-Dose CZT Study
S.M.Chang, MD
NCT01518777
Side Branch FFR After Provisional Stenting
Icahn School of Medicine at Mount Sinai
NCT03115580
Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery
Emory University
NCT04221594
Prasugrel Re-load Strategies
University of Florida
NCT01201772
The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes
Maine Center for Lipids and Cardiovascular Health
NCT00360217
Expression of Angiogenic Factors in Myocardial Tissue
University of Virginia
NCT01414621
Prophylactic Maze to Prevent Atrial Fibrillation in Adult Cardiac Surgery
Corewell Health West
NCT03604432
Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride
Kathirvel Subramaniam
NCT03270514
A Behavioral Science-Enhanced PHysician-led Remote Group Exercise InTervention for Women With Coronary Artery Disease
Brigham and Women's Hospital
NCT05611333
Magnetic Resonance Imaging (MRI) Viability: Comparison of Myocardial Viability by Positron Emission Tomography and MRI
Emory University
NCT00166179
Effect of Ile-Pro-Pro (IPP) on Endothelial Function in Patients With Coronary Artery Disease
Boston University
NCT00924157
Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease
Boston University
NCT01038362
High Ticagrelor Loading Dose in STEMI
University of Florida
NCT01898442
HemoSonics-UVA HemoSonics-UVA Cardiac Surgery Clinical Study Protocol
University of Virginia
NCT02456467
To Evaluate Safety, Pharmacokinetics and Pharmacodynamics of MEDI6012 in Subjects With Stable Coronary Artery Disease
MedImmune
NCT02601560
Comparison of Intravenous Adenosine Infusion With Regadenoson Bolus for Inducing Maximal Coronary Hyperemia
St. Louis University
NCT01161121
Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation
Mayo Clinic
NCT04992676
18F-fluoride (18F-NaF) PET for Identifying Coronary Atherosclerotic Plaques
Cedars-Sinai Medical Center
NCT02607748
VasoStat vs. TR Band for Radial Hemostasis
Forge Medical
NCT04163471
Platelet Sub-study of the TWILIGHT Trial
Juan Badimon
NCT04001374
Low Maintenance Dose Ticagrelor Versus Clopidogrel in Diabetes Patients Undergoing PCI
University of Florida
NCT03437044
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 17 |
| Phase 4 | 25 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Coronary Artery Disease Trial Landscape
220 indexed Coronary Artery Disease studies · 57 recruiting (26%).
Phase mix: 42 late (III/IV) vs 15 early (I/II).
Top sponsor: University of Florida (17 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Coronary Artery Disease?
PlainTrial tracks 220 US clinical trials for Coronary Artery Disease, of which 57 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Coronary Artery Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.