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ClinicalTrials.gov 57 recruiting now later-stage tilt #42 of 28,707 conditions

Coronary Artery Disease: later-stage trial registry

57 of 220 indexed Coronary Artery Disease trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #42 of 28,707 conditions by registered trial count.

220 US clinical trials · 57 currently recruiting · #42 of 28,707 conditions by registered trial count

Coronary Artery Disease: 220 US clinical trials tracked, 57 recruiting.

Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.

Enrollment posture brief

Registry condition coronary-artery-disease

OPEN 57 | RECR 26% | LATE 42 | EARLY 15 | RANK #42 | SPON 17

Nearest open-share peer: Adenocarcinoma (26% recruiting · 27 trials)

Autism Spectrum Disorder49.8%Mild Cognitive Impairment48.5%Sickle Cell Disease44.4%Coronary Artery Disease (thi…26%Diabetes Mellitus23.3%
Open-enrollment share among volume-matched conditions near Coronary Artery Disease

Coronary Artery Disease lists 57 open slots (26% of 220 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Coronary Artery Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Coronary Artery Disease is recruiting below its size-band peers.

    57 of 220 indexed trials (25.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Coronary Artery Disease trials is spread across many organizations.

    University of Florida accounts for 17 of 220 trials (7.7%). 134 distinct sponsors appear on at least one study for this condition label.

  3. Typical Coronary Artery Disease enrolment sits around 266 participants.

    Median target enrolment is 266 among the 220 trials that report a genuine target (sentinel values excluded). 70 of those (31.8%) plan for fewer than 100 participants.

  4. Coronary Artery Disease splits between interventional and observational designs.

    153 interventional and 67 observational studies make up this index (69.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 29Phase 317Phase 425

Open and recent trials

220 total, page 4 of 5

COMPLETED NA 184 participants

Comparing TR Band to Statseal in Conjunction With TR Band

VA Long Beach Healthcare System

NCT03028025

COMPLETED NA 179 participants

Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)

Johns Hopkins University

NCT00353795

COMPLETED 178 participants

Evaluation Using Computed Tomography Angiography (CTA) to Investigate and Detect Atherosclerotic Graft Disease (ELUCIDATE)

Corewell Health East

NCT00580008

COMPLETED NA 170 participants

Sapphire 3 CTO Study

OrbusNeich

NCT06358508

COMPLETED Phase 2 150 participants

Familiarization and Safety Study of PB127 Ultrasound Contrast Agent

Point Biomedical

NCT00594698

COMPLETED NA 150 participants

Stress CT Perfusion in Patients With Chest Pain

University of Chicago

NCT01969916

COMPLETED NA 150 participants

Left Versus Right Radial Artery and Radiation Exposure in Patients With Predictors of Trans-radial Failure

NYU Langone Health

NCT01707524

COMPLETED NA 145 participants

Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)

Shockwave Medical

NCT05966662

COMPLETED Phase 4 137 participants

Effect of Evolocumab on Coronary Plaque Characteristics

Annapoorna Kini

NCT04710368

COMPLETED 123 participants

Age and Endothelial Progenitor Cell Mobilization

Emory University

NCT00585949

COMPLETED Phase 3 120 participants

Cardiovascular Outcomes Of Diet Counseling

The Camelot Foundation

NCT00324545

COMPLETED NA 115 participants

Secondary Prevention After Coronary Bypass Surgery

Jeffrey Kramer, MD

NCT00843089

COMPLETED Phase 3 110 participants

Myocardial Ischemia and Transfusion Pilot

Rutgers, The State University of New Jersey

NCT01167582

COMPLETED Phase 2 110 participants

Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent

Marc Sakwa, MD

NCT01681095

COMPLETED NA 107 participants

Abbott Next Generation Drug Eluting Stent 48mm Study

Abbott Medical Devices

NCT04282148

COMPLETED Phase 4 105 participants

Ticagrelor With and Without Aspirin in Patients With Diabetes Mellitus

University of Florida

NCT04484259

COMPLETED NA 102 participants

Rapid Stress/Rest Single-Day Tc-99m Sestamibi Myocardial Single Photon Emission Computed Tomography

St. Luke's-Roosevelt Hospital Center

NCT01434641

COMPLETED 102 participants

Comparing Blood Loss, RBC Transfusions and Inflammatory Marker Changes Among Methods of CPB

Baylor Research Institute

NCT01083914

COMPLETED NA 100 participants

Vegan vs AHA Diet on Inflammation and Glucometabolic Profile in Patients With CAD

NYU Langone Health

NCT02135939

COMPLETED NA 96 participants

Vitamin D Repletion in Coronary Artery Disease

Seth I. Sokol, M.D.

NCT01570309

COMPLETED NA 94 participants

The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions in Small Vessels

Boston Scientific Corporation

NCT01498692

COMPLETED NA 93 participants

AngioSculpt® Coronary Bifurcation Study

AngioScore

NCT00686647

COMPLETED Early Phase 1 92 participants

Aspirin Resistance in Coronary Artery Disease

Vanderbilt University

NCT00753935

COMPLETED Phase 4 87 participants

Reduction in YEllow Plaque by Aggressive Lipid LOWering Therapy

Annapoorna Kini

NCT01567826

COMPLETED Phase 4 87 participants

Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease

University of Florida

NCT02287909

COMPLETED NA 80 participants

Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease

Johns Hopkins University

NCT04272060

COMPLETED NA 80 participants

Evaluation of Pharmacist Interventions in Lipid Management for Secondary Prevention

Wake Forest University Health Sciences

NCT06647238

COMPLETED 75 participants

HCR vs. CABG Study

Emory University

NCT02892474

COMPLETED 75 participants

Observational Study of the Association Between Periodontal Disease and Cardiovascular Disease

Texas Tech University Health Sciences Center

NCT02177591

COMPLETED NA 74 participants

Reducing Radioisotope Dose: the Half-Dose CZT Study

S.M.Chang, MD

NCT01518777

COMPLETED NA 71 participants

Side Branch FFR After Provisional Stenting

Icahn School of Medicine at Mount Sinai

NCT03115580

COMPLETED 68 participants

Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery

Emory University

NCT04221594

COMPLETED Phase 4 65 participants

Prasugrel Re-load Strategies

University of Florida

NCT01201772

COMPLETED NA 60 participants

The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes

Maine Center for Lipids and Cardiovascular Health

NCT00360217

COMPLETED 60 participants

Expression of Angiogenic Factors in Myocardial Tissue

University of Virginia

NCT01414621

COMPLETED NA 60 participants

Prophylactic Maze to Prevent Atrial Fibrillation in Adult Cardiac Surgery

Corewell Health West

NCT03604432

COMPLETED Phase 3 60 participants

Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride

Kathirvel Subramaniam

NCT03270514

COMPLETED NA 59 participants

A Behavioral Science-Enhanced PHysician-led Remote Group Exercise InTervention for Women With Coronary Artery Disease

Brigham and Women's Hospital

NCT05611333

COMPLETED 57 participants

Magnetic Resonance Imaging (MRI) Viability: Comparison of Myocardial Viability by Positron Emission Tomography and MRI

Emory University

NCT00166179

COMPLETED NA 54 participants

Effect of Ile-Pro-Pro (IPP) on Endothelial Function in Patients With Coronary Artery Disease

Boston University

NCT00924157

COMPLETED NA 52 participants

Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease

Boston University

NCT01038362

COMPLETED Phase 2 52 participants

High Ticagrelor Loading Dose in STEMI

University of Florida

NCT01898442

COMPLETED 50 participants

HemoSonics-UVA HemoSonics-UVA Cardiac Surgery Clinical Study Protocol

University of Virginia

NCT02456467

COMPLETED Phase 2 48 participants

To Evaluate Safety, Pharmacokinetics and Pharmacodynamics of MEDI6012 in Subjects With Stable Coronary Artery Disease

MedImmune

NCT02601560

COMPLETED Phase 1 46 participants

Comparison of Intravenous Adenosine Infusion With Regadenoson Bolus for Inducing Maximal Coronary Hyperemia

St. Louis University

NCT01161121

COMPLETED 43 participants

Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation

Mayo Clinic

NCT04992676

COMPLETED Phase 4 41 participants

18F-fluoride (18F-NaF) PET for Identifying Coronary Atherosclerotic Plaques

Cedars-Sinai Medical Center

NCT02607748

COMPLETED 40 participants

VasoStat vs. TR Band for Radial Hemostasis

Forge Medical

NCT04163471

COMPLETED 40 participants

Platelet Sub-study of the TWILIGHT Trial

Juan Badimon

NCT04001374

COMPLETED Phase 4 40 participants

Low Maintenance Dose Ticagrelor Versus Clopidogrel in Diabetes Patients Undergoing PCI

University of Florida

NCT03437044

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 9
Phase 3 17
Phase 4 25

Named interventions

Most-linked intervention names on Coronary Artery Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
7 trials
Ticagrelor Drug
4 trials
Placebo Other
4 trials
Colchicine Drug
3 trials
Clopidogrel Drug
3 trials
PROMUS Element Coronary Stent System Device
2 trials
Corus CAD (ASGES) Diagnostic test
2 trials
Percutaneous coronary intervention Device
2 trials

US sites by state

Facility locations filed on Coronary Artery Disease trials. A trial with sites in several states counts in each.

California 75 trials
New York 61 trials
Florida 58 trials
Georgia 40 trials
Massachusetts 36 trials
Minnesota 31 trials
Illinois 30 trials
Ohio 29 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Coronary Artery Disease page

220 registered trials, 57 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 57 Coronary Artery Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • University of Florida sponsors the most Coronary Artery Disease trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Coronary Artery Disease condition card totals 220 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.