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NCT04221594 · ClinicalTrials.gov registry record

Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery

A clinical trial of Coronary Artery Disease, sponsored by Emory University.

Completed
Registry status
68
Enrollment target
6
Study locations

NCT04221594: Completed study of Coronary Artery Disease, sponsored by Emory University.

NCT04221594 is a study of Coronary Artery Disease that has completed, run by Emory University. The registered enrollment target is 68 participants, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (95% lower). The trial reports 6 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04221594, a study of Coronary Artery Disease, has completed, sponsored by Emory University.

COMPLETED
Registry status
68 participants
Enrollment target
6
Study locations

Study Summary

This observational prospective clinical study is to develop software tools to fuse coronary anatomy data obtained from CT coronary angiography with dynamic PET data to noninvasively measure absolute myocardial blood flow, flow reserve and relative flow reserve across specific coronary lesions. Results will be compared to those obtained invasively in the catheterization laboratory.

Primary Outcome

Myocardial blood flow (MBF) measured in milliliters per minute per gram of tissue is providing unique pathophysiologic and diagnostic information on the function of the coronary macro- and microcirculation.

Conditions Studied

Coronary Artery Disease

Interventions

  • PROCEDURE Invasive Cardiac Catheterization (ICA)
  • PROCEDURE Coronary Computed Tomographic Angiogram (CCTA)
  • PROCEDURE Dynamic Cardiac Positron Emission Tomography (dPET)

Study Locations (6)

Other

  • Chonnam National University - Gwangju
  • Samsung Medical Center - Seoul
  • Seoul National University Hospital - Seoul

Georgia

  • Emory Clinic - Atlanta
  • Emory University Hospital - Atlanta

New York

  • Saint Francis Hospital & Heart Center - Roslyn

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2019-11-01
Est. Completion 2023-06-30
Emory University

1,208 total trials

What the finished NCT04221594 record still lists

NCT04221594 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Coronary Artery Disease appearing as the primary indexed condition, and to 3 interventions - of which Invasive Cardiac Catheterization (ICA) is the first listed.

NCT04221594 lists 6 locations in 3 states (Other, Georgia, New York).

Frequently Asked Questions

What is clinical trial NCT04221594 about?

NCT04221594 is a clinical study titled "Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery". This observational prospective clinical study is to develop software tools to fuse coronary anatomy data obtained from CT coronary angiography with dynamic PET data to noninvasively measure absolute myocardial blood flow, flow reserve and relative flow reserve across specific coronary lesions. Resul...

What is the current status of trial NCT04221594?

This trial is currently completed. The enrollment target is 68 participants. The study started on 2019-11-01. Estimated completion is 2023-06-30.

What conditions does trial NCT04221594 study?

This clinical trial studies the following conditions: Coronary Artery Disease.

What interventions are being tested in trial NCT04221594?

The interventions under investigation include: Invasive Cardiac Catheterization (ICA) (PROCEDURE), Coronary Computed Tomographic Angiogram (CCTA) (PROCEDURE), Dynamic Cardiac Positron Emission Tomography (dPET) (PROCEDURE).

Who is sponsoring clinical trial NCT04221594?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04221594 being conducted?

This trial has 6 study locations across Georgia, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Coronary Artery Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04221594's enrollment target sits among peer trials

68 166th of 219 higher than 53 of 219 other Coronary Artery Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT04221594, the US trial registry maintained by the National Library of Medicine. NCT04221594 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.