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NCT01414621 · ClinicalTrials.gov registry record

Expression of Angiogenic Factors in Myocardial Tissue

A clinical trial of Coronary Artery Disease, sponsored by University of Virginia.

Completed
Registry status
60
Enrollment target
1
Study location

NCT01414621: Completed study of Coronary Artery Disease, sponsored by University of Virginia.

NCT01414621 is a study of Coronary Artery Disease that has completed, run by University of Virginia. The registered enrollment target is 60 participants, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01414621, a study of Coronary Artery Disease, has completed, sponsored by University of Virginia.

COMPLETED
Registry status
60 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate whether angiogenesis is decreased in diabetic patients with coronary artery disease compared to non-diabetics with coronary artery disease. The protein expression of angiogenic factors will be examined in atrial tissue prior to initiation of cardiopulmonary bypass in patients undergoing coronary bypass surgery. The goal of this project is to evaluate the tissue levels of HIF-1, VEGF and angiostatin in diabetic and non-diabetic patients coming for on-pump coronary artery bypass graft (CABG).

Primary Outcome

The investigators will evaluate tissue levels of HIF-1, VEGF and angiostatin in diabetic and non-diabetic patients coming for on-pump CABG.

Conditions Studied

Interventions

  • OTHER atrial tissue sample

Study Locations (1)

Virginia

  • University of Virginia Health System - Charlottesville

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2009-08
Est. Completion 2011-08
University of Virginia

449 total trials

What the finished NCT01414621 record still lists

NCT01414621 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which atrial tissue sample is the first listed.

NCT01414621 reports a single indexed study location in Virginia.

Frequently Asked Questions

What is clinical trial NCT01414621 about?

NCT01414621 is a clinical study titled "Expression of Angiogenic Factors in Myocardial Tissue". The purpose of this study is to evaluate whether angiogenesis is decreased in diabetic patients with coronary artery disease compared to non-diabetics with coronary artery disease. The protein expression of angiogenic factors will be examined in atrial tissue prior to initiation of cardiopulmonary b...

What is the current status of trial NCT01414621?

This trial is currently completed. The enrollment target is 60 participants. The study started on 2009-08. Estimated completion is 2011-08.

What conditions does trial NCT01414621 study?

This clinical trial studies the following conditions: Coronary Artery Disease.

What interventions are being tested in trial NCT01414621?

The interventions under investigation include: atrial tissue sample (OTHER).

Who is sponsoring clinical trial NCT01414621?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01414621 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronary Artery Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01414621's enrollment target sits among peer trials

60 169th of 219 higher than 47 of 219 other Coronary Artery Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01414621, the US trial registry maintained by the National Library of Medicine. NCT01414621 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.