Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Coronary Artery Disease clinical trials
57 of 220 indexed Coronary Artery Disease trials are currently recruiting.
220 US clinical trials · 57 currently recruiting
Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.
The research picture
Coronary Artery Disease has 220 registered US clinical trials, 57 of them open to new participants right now, about 26% of the total.
- 57
- recruiting participants now
- 26%
- of trials open to enrollment
- 42
- in Phase 3–4 (later-stage)
- 17
- top sponsor: University of Florida
Active & Recent Trials
220 total, page 5 of 5
Comparison of StentOptimizer With IntraVenous Ultrasound and 2D Quantitative Coronary Angiography
Paieon
NCT00973921
Adenosine Dual Source Computed Tomography (CT) Versus Adenosine Single Photon Emission Computed Tomography (SPECT)
Cedars-Sinai Medical Center
NCT00892307
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
University of Louisville
NCT00474461
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Japanese Men
AstraZeneca
NCT03400488
The Influence of Febuxostat on Coronary Artery Endothelial Dysfunction in Participants With Chronic Stable Angina
Takeda
NCT01763996
Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants
National Human Genome Research Institute (NHGRI)
NCT01369953
Peripheral Nerve Blocks for Above-the-knee Amputations
University of Florida
NCT03404180
A Phase I Study in Healthy Volunteers to Evaluate the Safety of CardioPET™ in Detection of Coronary Artery Disease
Fluoropharma
NCT00413647
PET MYOCARDIAL Blood Flow Comparison to Coronary CTA and CT-FFR
Washington University School of Medicine
NCT05349084
Reversing Ticagrelor's Effects With Fresh Platelets
Icahn School of Medicine at Mount Sinai
NCT02201394
Implementing Myocardial Computed Tomographic Perfusion in a Community Hospital Setting
Lancaster General Hospital
NCT02756234
Evaluation of MyoStrain™ in Clinical Practice
University of Kansas Medical Center
NCT03825224
Impact of Timing of PD Assessments on Measures of Platelet Reactivity in Patients Undergoing PCI Treated With Cangrelor
University of Florida
NCT04668495
Effect of Cocoa Flavanols on Vascular Function
University of California, San Francisco
NCT00553774
Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-function: a Validation Study
University of Florida
NCT03489863
Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)
National Heart, Lung, and Blood Institute (NHLBI)
NCT02303067
Pharmacokinetics of Everolimus in Absorb BVS in Patients With Coronary Artery Lesions
Abbott Medical Devices
NCT02229864
Evaluation of Coronary Artery Calcification Using Gated Stationary Chest Tomosynthesis
University of North Carolina, Chapel Hill
NCT03169062
Assessment Of Vascular Health After Niacin Therapy (AVANT)
University of Pennsylvania
NCT02003638
Identification of Adverse Plaque Characteristics by Coronary MR Angiography
Cedars-Sinai Medical Center
NCT01986868
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 17 |
| Phase 4 | 25 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Coronary Artery Disease Trial Landscape
220 indexed Coronary Artery Disease studies · 57 recruiting (26%).
Phase mix: 42 late (III/IV) vs 15 early (I/II).
Top sponsor: University of Florida (17 trials), 9 others listed. 20 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Coronary Artery Disease?
PlainTrial tracks 220 US clinical trials for Coronary Artery Disease, of which 57 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Coronary Artery Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.