Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 57 recruiting now official registry

Coronary Artery Disease clinical trials

57 of 220 indexed Coronary Artery Disease trials are currently recruiting.

220 US clinical trials · 57 currently recruiting

Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.

The research picture

Coronary Artery Disease has 220 registered US clinical trials, 57 of them open to new participants right now, about 26% of the total.

57
recruiting participants now
26%
of trials open to enrollment
42
in Phase 3–4 (later-stage)
17
top sponsor: University of Florida
Phase 16Phase 29Phase 317Phase 425

Active & Recent Trials

220 total, page 5 of 5

COMPLETED 40 participants

Comparison of StentOptimizer With IntraVenous Ultrasound and 2D Quantitative Coronary Angiography

Paieon

NCT00973921

COMPLETED 34 participants

Adenosine Dual Source Computed Tomography (CT) Versus Adenosine Single Photon Emission Computed Tomography (SPECT)

Cedars-Sinai Medical Center

NCT00892307

COMPLETED Phase 1 33 participants

Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)

University of Louisville

NCT00474461

COMPLETED Phase 1 32 participants

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Japanese Men

AstraZeneca

NCT03400488

COMPLETED Phase 4 30 participants

The Influence of Febuxostat on Coronary Artery Endothelial Dysfunction in Participants With Chronic Stable Angina

Takeda

NCT01763996

COMPLETED 30 participants

Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants

National Human Genome Research Institute (NHGRI)

NCT01369953

COMPLETED Phase 4 30 participants

Peripheral Nerve Blocks for Above-the-knee Amputations

University of Florida

NCT03404180

COMPLETED Phase 1 21 participants

A Phase I Study in Healthy Volunteers to Evaluate the Safety of CardioPET™ in Detection of Coronary Artery Disease

Fluoropharma

NCT00413647

COMPLETED NA 21 participants

PET MYOCARDIAL Blood Flow Comparison to Coronary CTA and CT-FFR

Washington University School of Medicine

NCT05349084

COMPLETED Phase 4 20 participants

Reversing Ticagrelor's Effects With Fresh Platelets

Icahn School of Medicine at Mount Sinai

NCT02201394

COMPLETED 19 participants

Implementing Myocardial Computed Tomographic Perfusion in a Community Hospital Setting

Lancaster General Hospital

NCT02756234

COMPLETED 19 participants

Evaluation of MyoStrain™ in Clinical Practice

University of Kansas Medical Center

NCT03825224

COMPLETED 17 participants

Impact of Timing of PD Assessments on Measures of Platelet Reactivity in Patients Undergoing PCI Treated With Cangrelor

University of Florida

NCT04668495

COMPLETED Phase 1 16 participants

Effect of Cocoa Flavanols on Vascular Function

University of California, San Francisco

NCT00553774

COMPLETED Phase 4 14 participants

Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-function: a Validation Study

University of Florida

NCT03489863

COMPLETED 13 participants

Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)

National Heart, Lung, and Blood Institute (NHLBI)

NCT02303067

COMPLETED NA 12 participants

Pharmacokinetics of Everolimus in Absorb BVS in Patients With Coronary Artery Lesions

Abbott Medical Devices

NCT02229864

COMPLETED NA 10 participants

Evaluation of Coronary Artery Calcification Using Gated Stationary Chest Tomosynthesis

University of North Carolina, Chapel Hill

NCT03169062

COMPLETED NA 9 participants

Assessment Of Vascular Health After Niacin Therapy (AVANT)

University of Pennsylvania

NCT02003638

COMPLETED NA 2 participants

Identification of Adverse Plaque Characteristics by Coronary MR Angiography

Cedars-Sinai Medical Center

NCT01986868

← Previous Page 5 of 5

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 9
Phase 3 17
Phase 4 25

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Coronary Artery Disease Trial Landscape

220 indexed Coronary Artery Disease studies · 57 recruiting (26%).

Phase mix: 42 late (III/IV) vs 15 early (I/II).

Top sponsor: University of Florida (17 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Coronary Artery Disease?

PlainTrial tracks 220 US clinical trials for Coronary Artery Disease, of which 57 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Coronary Artery Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.