Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Arthroplasty, Replacement, Knee: early-phase trial registry
2 of 13 indexed Arthroplasty, Replacement, Knee trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 2 currently recruiting · #1,315 of 28,707 conditions by registered trial count
Arthroplasty, Replacement, Knee: 13 US clinical trials tracked, 2 recruiting.
Arthroplasty, Replacement, Knee is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.
Enrollment posture brief
Registry condition arthroplasty-replacement-knee
OPEN 2 | RECR 15% | LATE 0 | EARLY 1 | RANK #1315 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Cannabis Dependence (15% recruiting · 13 trials)
Arthroplasty, Replacement, Knee lists 2 open slots (15% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Arthroplasty, Replacement, Knee on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Arthroplasty, Replacement, Knee is recruiting below its size-band peers.
2 of 13 indexed trials (15.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Arthroplasty, Replacement, Knee research.
Northwestern University accounts for 2 of 13 trials (15.4%). 11 distinct sponsors appear on at least one study for this condition label.
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Typical Arthroplasty, Replacement, Knee enrolment sits around 150 participants.
Median target enrolment is 150 among the 13 trials that report a genuine target (sentinel values excluded). 5 of those (38.5%) plan for fewer than 100 participants.
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Arthroplasty, Replacement, Knee research is mostly interventional.
10 interventional and 3 observational studies make up this index (76.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
A Prospective, Single-arm, Trial to Determine Contamination Rates When Using an Antibacterial Incise Drape During Orthopedic Surgery
Solventum US
NCT07356323
Real-component Vs All-cement Articulating Spacers for Periprosthetic Knee Infection
Northwestern University
NCT06293352
TracPatch in Total Knee Arthroplasty
University of Miami
NCT03466476
Metal Ion Concentrations After Total Knee Arthroplasty
Mayo Clinic
NCT06447922
CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery
Stony Brook University
NCT05666479
X-3 Polyethylene Survival Outcomes Study
Mayo Clinic
NCT00493792
Preventing Persistent Post-Surgical Pain and Dysfunction
Barbara A Rakel
NCT03965897
Triathlon® Cruciate Retaining (CR) Total Knee System Outcomes Study
Stryker Orthopaedics
NCT00957723
Traditional vs Oral Fluid Management in Total Knee Arthroplasty
Colorado Joint Replacement
NCT03719378
Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
George Macrinici
NCT02218814
Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
Northwestern University
NCT02746874
Music Therapy Versus Control for Total Knee Arthroplasty
University of Alabama at Birmingham
NCT03569397
Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty
The University of Tennessee, Knoxville
NCT04103515
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Arthroplasty, Replacement, Knee records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Arthroplasty, Replacement, Knee trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Arthroplasty, Replacement, Knee page
13 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Arthroplasty, Replacement, Knee trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Northwestern University sponsors the most Arthroplasty, Replacement, Knee trials on record, review their full trial history before evaluating a specific study. See Northwestern University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Arthroplasty, Replacement, Knee condition card totals 13 registered trials; most-linked intervention Triathlon® CR Total Knee System; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.