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NCT03493516 · ClinicalTrials.gov registry record

Prediction of ARrhythmic Events With Positron Emission Tomography II

A clinical trial of Congestive Heart Failure and Ischemic Cardiomyopathy, sponsored by State University of New York at Buffalo.

Active
Registry status
302
Enrollment target
1
Study location

NCT03493516 is a study of Congestive Heart Failure and Ischemic Cardiomyopathy that is active but no longer recruiting, run by State University of New York at Buffalo. The registered enrollment target is 302 participants, roughly in line with the 324-participant average among 51 other Congestive Heart Failure trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT03493516, a study of Congestive Heart Failure and Ischemic Cardiomyopathy, is active but no longer recruiting, sponsored by State University of New York at Buffalo.

ACTIVE NOT RECRUITING
Registry status
302 participants
Enrollment target
1
Study location

Study Summary

Sudden cardiac death continues to be a major contributor to mortality in patients with ischemic cardiomyopathy. While implantable defibrillators can prevent death from ventricular arrhythmias, our current approach to identify patients at highest risk primarily rests on demonstrating a reduction in left ventricular ejection fraction less than 35%. The purpose of this observational cohort study is to prospectively test whether this can be enhanced by quantifying the amount of sympathetic denervation, left ventricular end-diastolic volume or brain natriuretic peptide levels.

Interventions

  • DIAGNOSTIC_TEST PET scan quantifying sympathetic denervation using [18F]-LMI1195

Study Locations (1)

New York

  • University at Buffalo Clinical and Translational Research Center - Buffalo

Trial Details

FieldValue
Enrollment Target 302 participants
Start Date 2018-04-08
Est. Completion 2026-12-31

What the Registry Record Tells You About NCT03493516

The ClinicalTrials.gov registry entry for NCT03493516 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 302 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 324-participant average among 51 other Congestive Heart Failure trials with a reported enrollment target. The listed sponsor is State University of New York at Buffalo, which has 243 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Congestive Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which PET scan quantifying sympathetic denervation using [18F]-LMI1195 is the first listed.

NCT03493516 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT03493516 about?

NCT03493516 is a clinical study titled "Prediction of ARrhythmic Events With Positron Emission Tomography II". Sudden cardiac death continues to be a major contributor to mortality in patients with ischemic cardiomyopathy. While implantable defibrillators can prevent death from ventricular arrhythmias, our current approach to identify patients at highest risk primarily rests on demonstrating a reduction in l...

What is the current status of trial NCT03493516?

This trial is currently active not recruiting. The enrollment target is 302 participants. The study started on 2018-04-08. Estimated completion is 2026-12-31.

What conditions does trial NCT03493516 study?

This clinical trial studies the following conditions: Congestive Heart Failure, Ischemic Cardiomyopathy, Sudden Cardiac Arrest.

What interventions are being tested in trial NCT03493516?

The interventions under investigation include: PET scan quantifying sympathetic denervation using [18F]-LMI1195 (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03493516?

This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03493516 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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