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NCT06680869 · ClinicalTrials.gov registry record · Phase 3

Early Amiodarone in Shockable Cardiac Arrest

A Phase 3 study of Cardiac Arrest, sponsored by Oregon Health and Science University.

Recruiting
Registry status
Phase 3
Development phase
585
Enrollment target
1
Study location

NCT06680869 is a Phase 3 study of Cardiac Arrest that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 585 participants, below the 1,461-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (60% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06680869, a Phase 3 study of Cardiac Arrest, is actively recruiting participants, sponsored by Oregon Health and Science University.

RECRUITING
Registry status
Phase 3
Development phase
585 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this pilot, pragmatic stepped-wedge cluster randomized trial is to evaluate if a modified cardiac arrest treatment algorithm calling for the administration of the initial amiodarone dose one 2-minute cycle earlier than current guidelines (during the same cycle as the initial dose of epinephrine) improves the time to amiodarone delivery in those with out-of-hospital cardiac arrest due to refractory ventricular fibrillation or ventricular tachycardia compared to usual care.

Conditions Studied

Interventions

  • DRUG Amiodarone Hydrochloride Injection
  • OTHER Usual Care Protocol

Study Locations (1)

Oregon

  • Oregon Health & Sciences University - Portland

Trial Details

FieldValue
Enrollment Target 585 participants
Start Date 2025-01-01
Est. Completion 2028-01-31
Phase Phase 3

What the Registry Record Tells You About NCT06680869

The ClinicalTrials.gov registry entry for NCT06680869 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 585 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,461-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (60% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cardiac Arrest appearing as the primary indexed condition, and to 2 interventions - of which Amiodarone Hydrochloride Injection is the first listed.

NCT06680869 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT06680869 about?

NCT06680869 is a clinical study titled "Early Amiodarone in Shockable Cardiac Arrest". The primary objective of this pilot, pragmatic stepped-wedge cluster randomized trial is to evaluate if a modified cardiac arrest treatment algorithm calling for the administration of the initial amiodarone dose one 2-minute cycle earlier than current guidelines (during the same cycle as the initial...

What is the current status of trial NCT06680869?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 585 participants. The study started on 2025-01-01. Estimated completion is 2028-01-31.

What conditions does trial NCT06680869 study?

This clinical trial studies the following conditions: Cardiac Arrest.

What interventions are being tested in trial NCT06680869?

The interventions under investigation include: Amiodarone Hydrochloride Injection (DRUG), Usual Care Protocol (OTHER).

Who is sponsoring clinical trial NCT06680869?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06680869 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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