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NCT06462027 · ClinicalTrials.gov registry record · Phase 1
Packed Red Blood Cell Transfusion During Cardiac Arrest
A Phase 1 study of Cardiac Arrest, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06462027: Recruiting Phase 1 study of Cardiac Arrest, sponsored by NYU Langone Health.
NCT06462027 is a Phase 1 study of Cardiac Arrest that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 30 participants, below the 1,479-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06462027, a Phase 1 study of Cardiac Arrest, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this pilot interventional study is to collect preliminary data on administering packed red blood cell (PRBC) during cardiac arrest (CA). The primary objective is to assess the feasibility of PRBC transfusion during cardiac CA to help optimize the methods required to augment cerebral and other vital organ oxygen delivery during cardiopulmonary resuscitation (CPR). The secondary objectives are to assess the effect of PRBC transfusion during prolonged cardiac arrests on cerebral oxygenation, end tidal carbon dioxide (ETCO2), return of spontaneous circulation (ROSC), survival to discharge, biomarkers of neural injury and inflammation, and neurological outcomes at hospital discharge, 30 days post-CA, and 90 days post-CA.
Conditions Studied
Interventions
- OTHER Saline
- DRUG Packed Red Blood Cells (1 unit)
- DRUG Packed Red Blood Cells (2 units)
Study Locations (1)
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-03-25 |
| Est. Completion | 2026-04-01 |
| Phase | Phase 1 |
What NCT06462027 shows while recruiting
NCT06462027 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,479-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Cardiac Arrest appearing as the primary indexed condition, and to 3 interventions - of which Saline is the first listed.
NCT06462027 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06462027 about?
NCT06462027 is a clinical study titled "Packed Red Blood Cell Transfusion During Cardiac Arrest". The purpose of this pilot interventional study is to collect preliminary data on administering packed red blood cell (PRBC) during cardiac arrest (CA). The primary objective is to assess the feasibility of PRBC transfusion during cardiac CA to help optimize the methods required to augment cerebral a...
What is the current status of trial NCT06462027?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2025-03-25. Estimated completion is 2026-04-01.
What conditions does trial NCT06462027 study?
This clinical trial studies the following conditions: Cardiac Arrest.
What interventions are being tested in trial NCT06462027?
The interventions under investigation include: Saline (OTHER), Packed Red Blood Cells (1 unit) (DRUG), Packed Red Blood Cells (2 units) (DRUG).
Who is sponsoring clinical trial NCT06462027?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06462027 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiac Arrest
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06462027's enrollment target sits among peer trials
30 25th of 31 higher than 7 of 31 other Cardiac Arrest trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Arrest trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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