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NCT00676585 · ClinicalTrials.gov registry record · Phase 1

Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest

A Phase 1 study of Cardiac Arrest, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
Phase 1
Development phase
50
Enrollment target
1
Study location

NCT00676585: Completed Phase 1 study of Cardiac Arrest, sponsored by Beth Israel Deaconess Medical Center.

NCT00676585 is a Phase 1 study of Cardiac Arrest that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 50 participants, below the 1,478-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00676585, a Phase 1 study of Cardiac Arrest, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
Phase 1
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

The major goal of this project is to determine whether the use of physiologic doses of corticosteroids will decrease time to shock reversal, alters the inflammatory cascade, and alters microcirculatory flow in post-cardiac arrest patients.

Primary Outcome

The primary outcome was time to shock reversal defined as at least 24 hours off all vasopressor medications.

Conditions Studied

Interventions

  • DRUG Hydrocortisone
  • DRUG Normal Saline

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2007-10
Est. Completion 2014-04
Phase Phase 1

What the finished NCT00676585 record still lists

NCT00676585 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,478-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Cardiac Arrest appearing as the primary indexed condition, and to 2 interventions - of which Hydrocortisone is the first listed.

NCT00676585 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00676585 about?

NCT00676585 is a clinical study titled "Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest". The major goal of this project is to determine whether the use of physiologic doses of corticosteroids will decrease time to shock reversal, alters the inflammatory cascade, and alters microcirculatory flow in post-cardiac arrest patients.

What is the current status of trial NCT00676585?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2007-10. Estimated completion is 2014-04.

What conditions does trial NCT00676585 study?

This clinical trial studies the following conditions: Cardiac Arrest.

What interventions are being tested in trial NCT00676585?

The interventions under investigation include: Hydrocortisone (DRUG), Normal Saline (DRUG).

Who is sponsoring clinical trial NCT00676585?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00676585 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiac Arrest

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00676585's enrollment target sits among peer trials

50 20th of 31 higher than 10 of 31 other Cardiac Arrest trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiac Arrest trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00676585, the US trial registry maintained by the National Library of Medicine. NCT00676585 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.